Cas no 57278-46-3 (7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid)
7-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a quinoline derivative with significant utility in pharmaceutical and chemical synthesis. Its core structure serves as a key intermediate in the preparation of antibacterial agents, particularly fluoroquinolone antibiotics. The compound features a carboxylic acid group at the 3-position and a chloro substituent at the 7-position, enhancing its reactivity for further functionalization. Its high purity and stability make it suitable for rigorous synthetic applications. The quinoline scaffold also offers potential for modifications, enabling the development of novel bioactive molecules. This compound is widely used in research and industrial settings due to its consistent performance and compatibility with diverse reaction conditions.
57278-46-3 structure
Product Name:7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS No:57278-46-3
MF:C10H6ClNO3
MW:223.612541675568
CID:946744
PubChem ID:66579
Update Time:2025-06-08
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Chemical and Physical Properties
Names and Identifiers
-
- 7-CHLORO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACID
- 7-chloro-1,4-dihydro-4-oxo-3-Quinolinecarboxylic acid
- 7-chloro-4-oxo-1H-quinoline-3-carboxylic acid
- 7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- NSC-27801
- 7-Chloro-4-Hydroxy Quinoline-3-Carboxylic acid
- AI3-23857
- SY033656
- NSC-56803
- Quinoline, 3-carboxy-4-hydroxy-7-chloro-
- EN300-186727
- DB-024476
- SB71573
- UNII-6897L5TD3T
- BDBM50404718
- AMY14619
- CHEMBL344461
- SCHEMBL1610495
- 86-47-5
- EINECS 201-673-5
- 57278-46-3
- 7-chloro-4-hydroxyquinoline-3-carboxylicacid
- AKOS005141866
- D81876
- NSC 27801
- 7-Chloro-4-hydroxy-quinoline-3-carboxylic acid
- 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-
- 6897L5TD3T
- USAF KF-16
- BBL027938
- MFCD08235113
- InChI=1/C10H6ClNO3/c11-5-1-2-6-8(3-5)12-4-7(9(6)13)10(14)15/h1-4H,(H,12,13)(H,14,15)
- DTXSID20235332
- AC-10982
- VS-08627
- NSC27801
- 7-Chloro-4-hydroxyquinoline-3-carboxylic acid
- MFCD00038080
- SACLIBNEKWTDEG-UHFFFAOYSA-
- 7-Chloro-4-hydroxy-3-quinolinecarboxylic acid, 97%
- DB-072272
- F2137-0001
- 7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
- STK802447
- 3-Carboxy-4-hydroxy-7-chloroquinoline
- CS-W013081
- NSC56803
- STK653911
- AKOS000275055
- 5-22-05-00286 (Beilstein Handbook Reference)
- NS00039128
- W-104067
- BRN 0171561
- G78827
- ALBB-030842
-
- MDL： MFCD00038080
- Inchi： 1S/C10H6ClNO3/c11-5-1-2-6-8(3-5)12-4-7(9(6)13)10(14)15/h1-4H,(H,12,13)(H,14,15)
- InChI Key： SACLIBNEKWTDEG-UHFFFAOYSA-N
- SMILES： ClC1C=CC2C(C(C(=O)O)=CNC=2C=1)=O
Computed Properties
- Exact Mass: 223.004
- Monoisotopic Mass: 223.004
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 1
- Complexity: 340
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.4A^2
- XLogP3: 2.5
Experimental Properties
- Density: 1.6±0.1 g/cm3
- Melting Point: Not available
- Boiling Point: 416.5±45.0 °C at 760 mmHg
- Flash Point: 205.7±28.7 °C
- Refractive Index: 1.648
- Vapor Pressure: 0.0±1.0 mmHg at 25°C
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Security Information
- Signal Word：warning
- Hazard Statement： H303+H313+H333
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A189006709-5g |
7-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 97% | 5g |
$1340.00 | 2023-09-01 | |
| Alichem | A189006709-10g |
7-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 97% | 10g |
$2170.80 | 2023-09-01 | |
| Alichem | A189006709-25g |
7-Chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 97% | 25g |
$3350.00 | 2023-09-01 | |
| Life Chemicals | F2137-0001-2μmol |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 2μmol |
$57.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-5μmol |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 5μmol |
$63.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-10μmol |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 10μmol |
$69.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-20μmol |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 20μmol |
$79.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-1mg |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 1mg |
$54.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-2mg |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 2mg |
$59.0 | 2023-07-28 | |
| Life Chemicals | F2137-0001-3mg |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
57278-46-3 | 90%+ | 3mg |
$63.0 | 2023-07-28 |
7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:57278-46-3)4-羥基-7-氯喹啉-3-羧酸
Order Number:LE27051140
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 13:02
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7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Related Literature
-
José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
-
Ying Li,Weirong Yao,Yunfei Xie,Renjun Pei RSC Adv., 2015,5, 98724-98729
-
Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
-
M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
-
Jianyao Huang,Dong Gao,Zhihui Chen,Weifeng Zhang Polym. Chem., 2021,12, 2471-2480
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Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:57278-46-3)4-羥基-7-氯喹啉-3-羧酸
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry