Cas no 56125-49-6 (N-(3-Aminopropyl)-4-methylbenzenesulfonamide)

N-(3-Aminopropyl)-4-methylbenzenesulfonamide is a sulfonamide derivative featuring both an aromatic tosyl group and a terminal primary amine. This bifunctional structure makes it a versatile intermediate in organic synthesis, particularly for the preparation of amides, ureas, and other nitrogen-containing compounds. The compound's amine group allows for further functionalization, while the sulfonamide moiety enhances stability and influences reactivity. It is commonly employed in pharmaceutical and agrochemical research due to its ability to act as a building block for bioactive molecules. The product is typically supplied as a high-purity solid, ensuring consistent performance in synthetic applications. Proper handling under inert conditions is recommended to preserve its reactivity.
N-(3-Aminopropyl)-4-methylbenzenesulfonamide structure
56125-49-6 structure
Product Name:N-(3-Aminopropyl)-4-methylbenzenesulfonamide
CAS No:56125-49-6
MF:C10H16N2O2S
MW:228.311241149902
MDL:MFCD03634548
CID:1086543
PubChem ID:15444563
Update Time:2025-05-20

N-(3-Aminopropyl)-4-methylbenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • N-(3-Aminopropyl)-4-methylbenzenesulfonamide
    • 3-tosylamino-propylamine
    • N-(3-aminopropyl)-4-methylbenzenesulfonamide(SALTDATA: FREE)
    • SCHEMBL7628596
    • DTXSID70572840
    • MFCD03634548
    • STK259948
    • G54661
    • 56125-49-6
    • tosyltrimethylenediamine
    • DB-352312
    • N-(3-Aminopropyl)-4-methylbenzene-1-sulfonamide
    • CHEMBL2448847
    • CHEMBRDG-BB 7371746
    • EN300-57715
    • AKOS000202174
    • BS-38058
    • MDL： MFCD03634548
    • Inchi： 1S/C10H16N2O2S/c1-9-3-5-10(6-4-9)15(13,14)12-8-2-7-11/h3-6,12H,2,7-8,11H2,1H3
    • InChI Key： CYKXMJPJALYMBC-UHFFFAOYSA-N
    • SMILES： S(C1C=CC(C)=CC=1)(NCCCN)(=O)=O

Computed Properties

  • Exact Mass: 228.09300
  • Monoisotopic Mass: 228.09324893g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 5
  • Complexity: 264
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.7
  • Topological Polar Surface Area: 80.6?2

Experimental Properties

  • PSA: 80.57000
  • LogP: 2.79410

N-(3-Aminopropyl)-4-methylbenzenesulfonamide Customs Data

  • HS CODE：2935009090
  • Customs Data：

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

N-(3-Aminopropyl)-4-methylbenzenesulfonamide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
B406565-100mg
N-(3-Aminopropyl)-4-methylbenzenesulfonamide
 56125-49-6
100mg
 $ 70.00 2022-06-07
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B406565-500mg
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500mg
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AB221501-250 mg
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 €159.10 2023-05-20
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AB221501-1 g
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 €217.60 2023-05-20
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AB221501-5 g
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abcr
AB221501-250mg
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 56125-49-6 95%
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 €230.10 2025-04-17
abcr
AB221501-5g
N-(3-Aminopropyl)-4-methylbenzenesulfonamide, 95%; .
 56125-49-6 95%
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 €749.60 2025-04-17
eNovation Chemicals LLC
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N-(3-Aminopropyl)-4-methylbenzenesulfonamide Related Literature

Additional information on N-(3-Aminopropyl)-4-methylbenzenesulfonamide

N-(3-Aminopropyl)-4-methylbenzenesulfonamide: A Comprehensive Overview

N-(3-Aminopropyl)-4-methylbenzenesulfonamide, also known by its CAS No. 56125-49-6, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound is characterized by its unique structure, which combines a sulfonamide group with an aromatic ring and an aminoalkyl chain. The molecule's structure allows for diverse applications, particularly in drug design and material science.

The synthesis of N-(3-Aminopropyl)-4-methylbenzenesulfonamide involves a series of well-established organic reactions, including nucleophilic substitution and coupling reactions. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses, reducing production costs and minimizing waste. These improvements have made the compound more accessible for research and industrial applications.

One of the most promising areas of research involving this compound is its application in drug delivery systems. The sulfonamide group is known for its ability to form stable bonds with various biomolecules, making it an ideal candidate for targeted drug delivery. Recent studies have demonstrated that N-(3-Aminopropyl)-4-methylbenzenesulfonamide can serve as a versatile linker in the construction of bioconjugates, enhancing the specificity and efficacy of therapeutic agents.

In addition to its role in pharmacology, this compound has also found applications in polymer chemistry. The aminoalkyl chain provides the molecule with amphiphilic properties, enabling it to act as a compatibilizer in polymer blends. This functionality has led to its use in improving the mechanical properties of polymeric materials, particularly in high-performance composites used in aerospace and automotive industries.

Recent research has also explored the potential of N-(3-Aminopropyl)-4-methylbenzenesulfonamide as a catalyst in organic synthesis. Its ability to facilitate nucleophilic substitutions and condensation reactions has been leveraged to develop novel synthetic pathways for complex molecules. This discovery underscores the compound's versatility and highlights its potential as a valuable tool in green chemistry.

The physical and chemical properties of this compound have been extensively studied, providing insights into its stability, solubility, and reactivity under various conditions. For instance, its high thermal stability makes it suitable for use in high-temperature applications, while its moderate solubility in organic solvents facilitates its handling during synthesis and purification processes.

In conclusion, N-(3-Aminopropyl)-4-methylbenzenesulfonamide (CAS No. 56125-49-6) is a multifaceted compound with a wide range of applications across different scientific disciplines. Its unique structure, combined with recent advancements in synthesis and application techniques, positions it as a key player in both academic research and industrial innovation.

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