Cas no 55974-34-0 (1-(2-Methylphenyl)piperazine Dihydrochloride)

1-(2-Methylphenyl)piperazine Dihydrochloride is a chemically synthesized organic compound primarily utilized in pharmaceutical and biochemical research. Its dihydrochloride salt form enhances stability and solubility, making it suitable for experimental applications. The compound serves as a key intermediate in the development of pharmacologically active molecules, particularly in studies involving serotonin and dopamine receptor interactions. Its structural features, including the methylphenyl and piperazine moieties, contribute to its utility in ligand-binding assays and structure-activity relationship (SAR) investigations. The high purity and well-defined composition ensure reproducibility in research settings. Proper handling and storage under controlled conditions are recommended to maintain its integrity.
1-(2-Methylphenyl)piperazine Dihydrochloride structure
55974-34-0 structure
Product Name:1-(2-Methylphenyl)piperazine Dihydrochloride
CAS No:55974-34-0
MF:C11H18Cl2N2
MW:249.180020809174
CID:375631
PubChem ID:91964
Update Time:2025-10-23

1-(2-Methylphenyl)piperazine Dihydrochloride Chemical and Physical Properties

Names and Identifiers

    • Piperazine,1-(2-methylphenyl)-, hydrochloride (1:2)
    • 1-(2-methylphenyl)piperazine,dihydrochloride
    • 1-(O-TOLYL)PIPERAZINE DIHYDROCHLORIDE
    • (2-methylphenyl)piperazine,chloride,chloride
    • 1-(2-methylphenyl)-piperazine dihydrochloride
    • 1-(o-Tolyl)piperazine HCl
    • 1-o-tolylpiperazine 2 HCI
    • 4-(2-methyl-phenyl)piperazine dihydrochloride
    • EINECS 259-930-2
    • 1-(o-tolyl)piperazine dihydrochloride, AldrichCPR
    • FT-0640354
    • p-tolylpiperazine dihydrochloride
    • 6RL85N2QNX
    • LF-0560
    • 1-(o-tolyl)-piperazine dihydrochloride
    • AKOS015959012
    • DTXSID10204552
    • CS-0363701
    • Piperazine, 1-(2-methylphenyl)-, hydrochloride
    • 1-o-tolyl-piperazine dihydrochloride
    • SCHEMBL314296
    • 1-o-tolylpiperazine dihydrochloride
    • 1-o-tolyl-piperazine 2 HCl
    • MFCD00012759
    • 55974-34-0
    • NS00087084
    • 1-(2-tolyl)piperazine dihydrochloride
    • Piperazine, 1-(2-methylphenyl)-, hydrochloride (1:2)
    • AC-8853
    • 1-(2-methylphenyl)piperazine dihydrochloride
    • 1-(2-methylphenyl)piperazine;dihydrochloride
    • CCG-42343
    • 1-o-tolylpiperazine-1,4-diium chloride
    • NCENNBIPRYOJSP-UHFFFAOYSA-N
    • 1-(2-Methylphenyl)piperazine Dihydrochloride
    • MDL: MFCD00012759
    • Inchi: 1S/C11H16N2.2ClH/c1-10-4-2-3-5-11(10)13-8-6-12-7-9-13;;/h2-5,12H,6-9H2,1H3;2*1H
    • InChI Key: NCENNBIPRYOJSP-UHFFFAOYSA-N
    • SMILES: Cl.Cl.N1(C2C=CC=CC=2C)CCNCC1

Computed Properties

  • Exact Mass: 248.08500
  • Monoisotopic Mass: 248.085
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 152
  • Covalently-Bonded Unit Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 15.3A^2

Experimental Properties

  • Boiling Point: 301.6 °C at 760 mmHg
  • Flash Point: 301.6 °C at 760 mmHg
  • PSA: 15.27000
  • LogP: 3.40240

1-(2-Methylphenyl)piperazine Dihydrochloride Security Information

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1-(2-Methylphenyl)piperazine Dihydrochloride Suppliers

Amadis Chemical Company Limited
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(CAS:55974-34-0)1-(2-Methylphenyl)piperazine Dihydrochloride
Order Number:A1234100
Stock Status:in Stock
Quantity:50g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 19:14
Price ($):275

Additional information on 1-(2-Methylphenyl)piperazine Dihydrochloride

Comprehensive Overview of 1-(2-Methylphenyl)piperazine Dihydrochloride (CAS No. 55974-34-0)

1-(2-Methylphenyl)piperazine Dihydrochloride (CAS No. 55974-34-0) is a specialized organic compound widely utilized in pharmaceutical research and biochemical applications. This compound, often abbreviated as 2-MPP Dihydrochloride, belongs to the piperazine derivative family, known for their versatile roles in drug development and neuroscience studies. With its unique molecular structure featuring a methylphenyl group attached to a piperazine core, it has garnered significant attention for its potential in modulating receptor activity and enzyme interactions.

In recent years, the demand for piperazine derivatives like 1-(2-Methylphenyl)piperazine Dihydrochloride has surged due to their relevance in studying neurotransmitter systems. Researchers frequently explore its interactions with serotonin receptors and dopamine transporters, aligning with trending topics such as neuropharmacology and mental health therapeutics. The compound’s dihydrochloride salt form enhances solubility, making it ideal for in vitro and in vivo experiments, a feature highly valued in modern drug discovery pipelines.

One of the most searched questions in scientific forums revolves around the synthesis and purity of CAS 55974-34-0. High-purity grades (>98%) are critical for reproducible results, especially in assays targeting G-protein-coupled receptors (GPCRs). Analytical techniques like HPLC and NMR are commonly employed to verify its structural integrity, addressing concerns about batch-to-batch consistency—a hot topic among quality-conscious researchers.

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Beyond pharmacology, 1-(2-Methylphenyl)piperazine Dihydrochloride finds niche applications in chemical biology for probe design. Its ability to act as a ligand scaffold enables the development of targeted imaging agents, a trend driven by the rise of precision medicine. SEO-optimized terms like “fluorescent piperazine derivatives” and “receptor-binding tracers” resonate well here, as they mirror current academic and industrial priorities.

Regulatory compliance and safety are also frequently queried topics. While 55974-34-0 is not classified as hazardous under standard guidelines, proper personal protective equipment (PPE) and ventilation are recommended during handling. This addresses common search intent around “l(fā)ab safety protocols for dihydrochloride salts” and “non-toxic alternatives in receptor studies.”

In summary, 1-(2-Methylphenyl)piperazine Dihydrochloride (CAS No. 55974-34-0) stands at the intersection of cutting-edge research and practical utility. Its multifaceted applications—from neuroscience to molecular imaging—coupled with stringent quality requirements, make it a compound of enduring relevance. By addressing trending queries and emphasizing its scientific rigor, this overview aims to serve as a trusted resource for researchers and industry professionals alike.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:55974-34-0)1-(2-Methylphenyl)piperazine Dihydrochloride
A1234100
Purity:99%
Quantity:50g
Price ($):275
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