Cas no 5470-34-8 (4'-Methoxyformanilide)

4'-Methoxyformanilide is a synthetic organic compound characterized by the presence of a methoxy group at the para position of the aniline ring, coupled with a formamide functional group. This structure imparts unique reactivity, making it a valuable intermediate in pharmaceutical and fine chemical synthesis. Its electron-donating methoxy group enhances stability and influences regioselectivity in electrophilic aromatic substitution reactions. The compound is commonly utilized in the preparation of dyes, agrochemicals, and active pharmaceutical ingredients (APIs) due to its predictable reactivity and compatibility with various reaction conditions. High purity grades ensure consistent performance in demanding applications. Proper handling and storage under inert conditions are recommended to maintain its integrity.
4'-Methoxyformanilide structure
4'-Methoxyformanilide structure
Product Name:4'-Methoxyformanilide
CAS No:5470-34-8
MF:C8H9NO2
MW:151.162562131882
MDL:MFCD00086774
CID:368197
PubChem ID:87557814
Update Time:2025-05-24

4'-Methoxyformanilide Chemical and Physical Properties

Names and Identifiers

    • N-(4-Methoxyphenyl)formamide
    • 4'-Methoxyformanilide
    • 4'-METHOXYFORMANILIDE (EP)
    • Formamide,N-(4-methoxyphenyl)-
    • 4-methoxy-1-formanilide
    • 4-methoxylformanilide
    • N-Formyl-4-methoxyaniline
    • para-formamidoanisole
    • p-Formanisidide
    • Formamide, N-(4-methoxyphenyl)-
    • SXEVZVMJNXOXIJ-UHFFFAOYSA-N
    • p-formamido anisole
    • NSC26220
    • 4-Methoxyformanilide
    • 4-methoxy formanilide
    • 4-Methoxyphenylformamide
    • 4-Methoxyphenylformamide #
    • N-(4-methoxyphenyl)-formamide
    • N-(4-Methoxy-phenyl)-formamide
    • AI3-18915
    • NSC 26220
    • N-(4-Methoxyphenyl)formamide, 97%
    • EINECS 226-802-2
    • D91515
    • CS-0197277
    • 7DF25KCG5N
    • NSC-26220
    • CHEMBL3252138
    • A870377
    • SCHEMBL225907
    • DTXSID30203163
    • M1623
    • AKOS013153464
    • MFCD00086774
    • 5470-34-8
    • FT-0722230
    • NS00033180
    • ~{N}-(4-methoxyphenyl)methanamide
    • P-METHOXYFORMANILDE
    • 4''-Methoxyformanilide
    • MDL: MFCD00086774
    • Inchi: 1S/C8H9NO2/c1-11-8-4-2-7(3-5-8)9-6-10/h2-6H,1H3,(H,9,10)
    • InChI Key: SXEVZVMJNXOXIJ-UHFFFAOYSA-N
    • SMILES: O(C)C1C=CC(=CC=1)NC=O

Computed Properties

  • Exact Mass: 151.06300
  • Monoisotopic Mass: 151.063
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 119
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: 1
  • Topological Polar Surface Area: 38.3

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.2±0.1 g/cm3
  • Melting Point: 78.0 to 82.0 deg-C
  • Boiling Point: 159°C/5mmHg(lit.)
  • Flash Point: 150.5±23.2 °C
  • Refractive Index: 1.682
  • PSA: 38.33000
  • LogP: 1.97240
  • Solubility: Not determined
  • Vapor Pressure: 0.0±0.7 mmHg at 25°C

4'-Methoxyformanilide Security Information

4'-Methoxyformanilide Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4'-Methoxyformanilide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
M863398-1g
4'-Methoxyformanilide
5470-34-8 ≥98%(GC)
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150.30 2021-05-17
XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd.
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4'-Methoxyformanilide
5470-34-8 97%
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¥343.2 2022-02-24
TRC
M269563-50mg
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$ 50.00 2022-06-04
TRC
M269563-100mg
4'-Methoxyformanilide
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100mg
$ 65.00 2022-06-04
TRC
M269563-500mg
4'-Methoxyformanilide
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$ 80.00 2022-06-04
Apollo Scientific
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£25.00 2025-03-21
Apollo Scientific
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£79.00 2025-02-20
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
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¥430.00 2024-04-16
Apollo Scientific
OR922686-25g
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£278.00 2025-02-20
eNovation Chemicals LLC
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4'-Methoxyformanilide Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5470-34-8)4'-Methoxyformanilide
Order Number:A870377
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:22
Price ($):281.0

Additional information on 4'-Methoxyformanilide

Recent Advances in the Study of 4'-Methoxyformanilide (CAS: 5470-34-8): A Comprehensive Research Brief

4'-Methoxyformanilide (CAS: 5470-34-8) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. Recent studies have explored its potential applications in drug development, particularly as an intermediate in the synthesis of bioactive molecules. This research brief aims to summarize the latest findings related to 4'-Methoxyformanilide, focusing on its chemical properties, biological activities, and potential therapeutic applications.

One of the key areas of investigation has been the role of 4'-Methoxyformanilide in the synthesis of novel pharmaceutical compounds. Researchers have identified its utility as a building block in the production of derivatives with enhanced pharmacological properties. For instance, a 2023 study published in the Journal of Medicinal Chemistry demonstrated that 4'-Methoxyformanilide derivatives exhibit promising anti-inflammatory and analgesic effects in preclinical models, suggesting potential for further development into non-steroidal anti-inflammatory drugs (NSAIDs).

In addition to its pharmacological potential, recent research has also focused on the mechanistic insights of 4'-Methoxyformanilide. Advanced spectroscopic techniques, including NMR and mass spectrometry, have been employed to elucidate its molecular structure and interactions with biological targets. These studies have provided valuable data on the compound's stability, reactivity, and potential for modification to improve its bioactivity.

Another significant development is the exploration of 4'-Methoxyformanilide's role in cancer research. Preliminary studies have indicated that certain derivatives of this compound may exhibit cytotoxic effects on specific cancer cell lines. A 2024 study in Bioorganic & Medicinal Chemistry Letters reported that modified 4'-Methoxyformanilide analogs showed selective inhibition of tumor cell proliferation, highlighting its potential as a lead compound for anticancer drug discovery.

Despite these promising findings, challenges remain in the optimization of 4'-Methoxyformanilide-based therapeutics. Issues such as bioavailability, metabolic stability, and toxicity profiles need to be addressed through further research. Ongoing studies are employing computational modeling and high-throughput screening to identify the most promising derivatives for clinical development.

In conclusion, 4'-Methoxyformanilide (CAS: 5470-34-8) continues to be a compound of great interest in chemical biology and pharmaceutical research. Its versatility as a synthetic intermediate and its emerging biological activities make it a valuable subject for ongoing and future studies. As research progresses, it is anticipated that new applications and optimized derivatives of this compound will further enhance its therapeutic potential.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:5470-34-8)4'-Methoxyformanilide
A870377
Purity:99%
Quantity:25g
Price ($):281.0
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