• 1. The evolution of triphenylamine hole transport materials for efficient perovskite solar cells
  Afsaneh Farokhi,Hashem Shahroosvand,Gabriele Delle Monache,Melanie Pilkington,Mohammad Khaja Nazeeruddin Chem. Soc. Rev. 2022 51 5974
• 2. Metal-free synthesis of allylic amines by cross-dehydrogenative-coupling of 1,3-diarylpropenes with anilines and amides under mild conditions
  Zhiming Wang,Hanjie Mo,Dongping Cheng,Weiliang Bao Org. Biomol. Chem. 2012 10 4249
• 3. Copper-catalyzed sulfonylation of N-tosylhydrazones followed by a one-pot C–N bond formation
  Kena Zhang,Olivier Provot,Christine Tran,Mouad Alami,Abdallah Hamze Org. Biomol. Chem. 2021 19 5358
• 4. Polydentate hydrazones as multitasking catalysts in visible-light-induced coupling reactions of amines
  Ganghu Wang,Jianhua Zhang,Legen Hu,Jiaquan Wang,Chunyin Zhu Org. Biomol. Chem. 2023 21 754
• 5. Triphenylamine/tetrazine based π-conjugated systems as molecular donors for organic solar cells
  Cassandre Quinton,Valérie Alain-Rizzo,Cécile Dumas-Verdes,Gilles Clavier,Laurence Vignau,Pierre Audebert New J. Chem. 2015 39 9700

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Aminophenyl ethers
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

Comprehensive Overview of 4-Methoxy-N-phenylaniline (CAS No. 1208-86-2): Properties, Applications, and Industry Insights

4-Methoxy-N-phenylaniline (CAS No. 1208-86-2), also known as p-Methoxydiphenylamine, is a versatile organic compound widely utilized in pharmaceuticals, agrochemicals, and specialty chemical synthesis. This aromatic amine derivative features a methoxy group (-OCH₃) and a phenylamino (-NHPh) moiety, imparting unique reactivity and solubility properties. Its molecular formula, C₁₃H₁₃NO, and molecular weight of 199.25 g/mol make it a valuable intermediate in fine chemical manufacturing.

In recent years, the demand for 4-Methoxy-N-phenylaniline has surged due to its role in synthesizing advanced materials, such as liquid crystals and OLED (Organic Light-Emitting Diode) components. Researchers and manufacturers frequently search for "4-Methoxy-N-phenylaniline solubility," "CAS 1208-86-2 suppliers," and "p-Methoxydiphenylamine synthesis" to address formulation challenges. The compound's stability under mild conditions and compatibility with polar solvents like ethanol and acetone further enhance its industrial appeal.

The pharmaceutical industry leverages 4-Methoxy-N-phenylaniline as a precursor for drug candidates targeting neurological and inflammatory disorders. Its structural motif aligns with trends in "green chemistry" and "sustainable synthesis," as it enables atom-efficient reactions with reduced waste generation. Analytical techniques such as HPLC and GC-MS are commonly employed to verify the purity of CAS No. 1208-86-2, with typical commercial grades offering ≥98% purity.

Environmental and regulatory considerations are critical when handling 4-Methoxy-N-phenylaniline. While not classified as hazardous under major chemical inventories (e.g., REACH, TSCA), proper storage in amber glass containers under inert atmosphere is recommended to prevent oxidation. Users often inquire about "4-Methoxy-N-phenylaniline MSDS" and "biodegradability of aromatic amines" to ensure compliance with workplace safety standards.

Emerging applications in electronic materials have positioned 1208-86-2 as a key building block for conductive polymers. Its electron-donating methoxy group facilitates charge transport, making it relevant to "organic electronics research" and "flexible display technology." Patent literature reveals growing interest in derivatizing this compound for use in photovoltaic devices and sensors.

From a market perspective, the global supply chain for 4-Methoxy-N-phenylaniline remains robust, with major producers located in Asia, Europe, and North America. Quality control parameters such as "residual solvent limits" and "heavy metal content" dominate technical discussions among buyers. The compound's price volatility is often linked to raw material availability, particularly anisole and nitrobenzene derivatives used in its production.

Innovative purification methods, including recrystallization from hexane/ethyl acetate mixtures or column chromatography, continue to evolve for CAS 1208-86-2. These advancements address the need for ultra-high-purity material in sensitive applications like "medical device coatings" and "biocompatible polymers." Analytical data (FTIR, ¹H NMR) typically confirm the characteristic signals of the methoxy (δ 3.7-3.9 ppm) and aromatic protons (δ 6.8-7.4 ppm).

Future research directions for p-Methoxydiphenylamine may explore its potential in catalytic systems or as a ligand in transition metal complexes. The compound's balanced lipophilicity (LogP ~2.5) also makes it a candidate for "drug delivery optimization" studies. As industries prioritize "bio-based intermediates," derivatization routes using renewable feedstocks could further expand the utility of this structurally adaptable molecule.

• 101-64-4(1-N-(4-methoxyphenyl)benzene-1,4-diamine)
• 101-70-2(4,4'-Dimethoxydiphenylamine)
• 27151-57-1(Benzenamine,4-methoxy-N-(4-methoxyphenyl)-N-methyl-)
• 27151-54-8(4-(4-Methoxyphenyl)aminophenol)
• 3566-44-7(N-(P-Methoxyphenyl)-P-Phenylenediamine Hydrochloride)
• 54480-44-3(1,4-Benzenediamine, N'-(4-methoxyphenyl)-N,N-dimethyl-)
• 20440-94-2(4-Methoxy-N-(4-methoxyphenyl)-N-phenylaniline)
• 101-16-6(3-Methoxydiphenylamine)
• 4316-51-2(4-Methoxytriphenylamine)
• 24413-67-0(1,4-Benzenediamine,N1,N4-bis(4-methoxyphenyl)-)