Cas no 538-75-0 (N,N'-Dicyclohexylcarbodiimide)

N,N'-Dicyclohexylcarbodiimide (DCC) is a widely used carbodiimide coupling agent in organic synthesis, particularly for peptide bond formation via amide coupling reactions. Its primary advantage lies in its efficiency as a dehydrating agent, facilitating the condensation of carboxylic acids and amines to form amides or esters. DCC is highly stable under typical reaction conditions and offers selective reactivity, minimizing side reactions. It is commonly employed in the synthesis of peptides, pharmaceuticals, and polymers. The compound’s hydrophobic cyclohexyl groups enhance solubility in organic solvents, making it suitable for non-aqueous systems. Proper handling is required due to its potential to cause skin and respiratory irritation.
N,N'-Dicyclohexylcarbodiimide structure
N,N'-Dicyclohexylcarbodiimide structure
Product Name:N,N'-Dicyclohexylcarbodiimide
CAS No:538-75-0
MF:C13H22N2
MW:206.327183246613
MDL:MFCD00011659
CID:38152
PubChem ID:10868
Update Time:2025-09-11

N,N'-Dicyclohexylcarbodiimide Chemical and Physical Properties

Names and Identifiers

    • N,N'-Dicyclohexylcarbodiimide
    • N,N'-DICYLOHEXYLCARBODIIMIDE
    • N,N-DICYCHOHEXYLCARBODIIMIDE
    • N,N-DICYCLOHEXYL CARBODIIMIDE
    • 1,3-DICYCLOHEXYLCARBODIIMIDE
    • Bis(cyclohexyl)carbodiimide
    • DCCI
    • DCC
    • DCC (N,N-dichyclohexylcarbodiimide)
    • Dicyclohexylcarbodiimide
    • N,N’-Dicyclohexylcarbodiimide
    • N,N′-Dicyclohexylcarbodiimide
    • N,N'-dicyclohexylcarbodiimide(DCC)
    • N,N-dicyclohexylcarbodiimide(DCC)
    • N.N'-Dicyclohexylcarbodiimide
    • 1,3-di-cyclohexylcarbodiimide
    • dcc solution
    • DCCD
    • Dicyclimide
    • dicyclohexyl-carbodiimide
    • N,N‘-Dicyclohexylcarbodiimide
    • N,N‘-Dicyclohexylcarbodimide
    • N,N’-Dicyclohexylcarbodiimide (DCC)
    • N,N'-Dicyclohexylcarbodimide
    • N,N'-Methanediylidenedicyclohexanamine
    • N,N′-Methanetetraylbis[cyclohexanamine]
    • NSC 30022
    • NSC 53373
    • NSC 57182
    • N，N-二環(huán)己基碳二亞胺
    • DCC (25% in Pyridine, ca. 1.2mol/L)
    • NN'Dicyclohexylcarbodie
    • Carbodicyclohexylimide
    • n,n-dicyclohexylcarbodiimide
    • Cyclohexanamine, N,N'-methanetetraylbis-
    • Carbodiimide, dicyclohexyl-
    • Dicylcohexylcarbodiimide
    • N,N'-Methanetetraylbiscyclohexaamine
    • dicyclohexylmethanediimine
    • N,N'-Dicyclohexylcarbodiimide (DCC)
    • N,N'-dicyclohexylmethanediimine
    • Dicyclohex
    • Epitope ID:114067
    • n,n'-dicyclohexylcarbodiimid
    • D0437
    • 1,3-dicyclo-hexylcarbodiimide
    • 0T1427205E
    • N, N'-dicyclohexylcarbodimide
    • D0436
    • NSC53373
    • C13H22N2
    • dicyciohexylcarbodiimide
    • Q306565
    • 1,3-dicyclohexylcarbodiimid
    • Tox21_203000
    • DICYCLOHEXYLCARBODIIMIDE [MI]
    • AM83818
    • CHEMBL162598
    • CARBODIIMIDE,DICYCLOHEXYL
    • NCGC00091497-03
    • 1,3-dicyclohexyl-carbodiimide
    • N,N'-methanediylidene-dicyclohexanamine
    • C93487
    • NSC-57182
    • Q-200966
    • N,N'-DICYCLOHEXYL-CARBODIIMIDE
    • Methanediimine, N,N'-dicyclohexyl-
    • AKOS000120067
    • US8815951, dicyclohexylcarbodiimide
    • NS00003057
    • CCRIS 9266
    • Dicyclimide;1,3-dicyclohexylcarbodiimide;N,N-Dicyclohexylcarbodiimide;N,N'-Methanediylidenedicyclohexanamine
    • N,N'dicyclohexylcarbodiimide
    • 1,3-dicyclohexylcarbo-diimide
    • FT-0629452
    • NSC-30022
    • AI3-08191
    • NSC57182
    • US8815951, N/A
    • n,n'-dicyclohexyl carbodiimide
    • 1, 3-dicyclohexylcarbodiimide
    • DCC, puriss., >=99.0% (GC)
    • BDBM129231
    • NCGC00260545-01
    • NCGC00091497-04
    • dicyclohexylcarbod iimide
    • HY-Y1092
    • Dicyclohexyicarbodiimide
    • 1,3-dicyclohexylcarbodimide
    • N.N' - dicyclohexylcarbodiimide
    • N, N'dicyclohexylcarbodimide
    • 1,N'-dicyclohexylcarbodimide
    • dicyclohexyl carbodimide
    • Dicylcohexylcarbodimide
    • DTXSID1023817
    • F0001-1397
    • dicyclohexylcarbo-diimide
    • Cyclohexaamine, N,N'-methanetetraylbis-
    • DTXCID003817
    • Z104477564
    • NCGC00091497-02
    • Dicyclohexyl-carboxydilmide
    • N,N'- dicyclohexyl carbodiimide
    • DCC, 1.0 M in methylene chloride
    • EINECS 208-704-1
    • N,N,-dichyclohexyl-carbodiimide
    • dicyclohexyl carbodiimide
    • DCC, 99%
    • 538-75-0
    • CAS-538-75-0
    • Dicyclohexyl carbo diimide
    • NSC30022
    • N-((cyclohexylimino)methylene) cyclohexanamine
    • N, N'-dicyclohexylcarbodiimide
    • N-(N-cyclohexylcarboximidoyl)cyclohexanamine
    • dicyclo-hexylcarbodiimide
    • NCGC00091497-01
    • N-((cyclohexylimino)methylene)cyclohexanamine
    • 1,3- dicyclohexylcarbodiimide
    • 1,3-dicyclo hexyl carbodiimide
    • HSDB 8049
    • N, N'-dicyclohexyl carbodiimide
    • 4-12-00-00072 (Beilstein Handbook Reference)
    • 1,3-di-cyclohexyl carbodiimide
    • 1.3-dicyclohexylcarbodiimide
    • N,N'-dicyclo hexyl carbodiimide
    • n,n-dichyclohexylcarbodiimide
    • N,N'-Dicyclohexyl carbodimide
    • MFCD00011659
    • dicyclohexylcarbodiimid
    • InChI=1/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H
    • dicyclohe-xylcarbodiimide
    • 1.3-dicyclohexylcarbodimide
    • NSC-53373
    • dicyclohexylcarbodimide
    • SCHEMBL303
    • NCGC00257167-01
    • BP-13398
    • DCC Crosslinker
    • 1,3-dicyclohexyl- carbodiimide
    • N,N'-dicyclo-hexylcarbodiimide
    • CS-W020097
    • BRN 0610662
    • 1,3dicyclohexylcarbodiimide
    • UNII-0T1427205E
    • 1,3-dicyclohexyl carbodiimide
    • DICYCLOHEXYLCARBODIIMIDE [HSDB]
    • 1,3-dicyclohexyl carbo-diimide
    • N,N'-Methanetetraylbiscyclohexanamine
    • dicylohexylcarbodiimide
    • EN300-20280
    • Tox21_303237
    • dicylohexyl-carbodiimide
    • 1,3-dicylcohexylcarbodiimide
    • N,N'-dicylcohexylcarbodiimide
    • dicyclohexylcarbodi-imide
    • Cyclohexanamine,N'-methanetetraylbis-
    • N,N'-dicyclo hexylcarbodiimide
    • EC 208-704-1
    • CHEBI:53090
    • Cyclohexaamine, N,N'methanetetraylbis (9CI)
    • STL089892
    • Cyclohexaamine, N,N'methanetetraylbis
    • Cyclohexanamine, N,N'methanetetraylbis
    • Carbodiimide, dicyclohexyl
    • DB-002694
    • N,N'-Meth-anetetraylbiscyclohexanamine
    • Cyclohexaamine, N,N'-methanetetraylbis-(9CI)
    • N,N'Methanetetraylbiscyclohexaamine
    • DICYCLOCARBODIIMIDE
    • BBL012208
    • 1,3-Dicyclohexylcarbodiimide solution (50% in THF)
    • N,N inverted exclamation marka-Dicyclohexylcarbodiimide
    • FD05508
    • 1,3-Dicyclohexyl carbodiimide;N,N'-Dicyclohexylcarbodiimide
    • 208-704-1
    • 1,3-Dicyclohexylcarbodiimide solution (1.0 M in methylene chloride)
    • MDL： MFCD00011659
    • Inchi： 1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
    • InChI Key： QOSSAOTZNIDXMA-UHFFFAOYSA-N
    • SMILES： N(=C=NC1CCCCC1)C1CCCCC1
    • BRN： 610662

Computed Properties

  • Exact Mass: 206.17800
  • Monoisotopic Mass: 206.178299
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 201
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 4.7
  • Topological Polar Surface Area: 24.7

Experimental Properties

  • Color/Form: White crystal or yellowish transparent liquid
  • Density: 1.247?g/mL?at 25?°C
  • Melting Point: 34-35?°C (lit.)
  • Boiling Point: 122-124?°C/6?mmHg(lit.)
  • Flash Point: Degrees Fahrenheit:235.4°F
    Degrees Celsius:113°C
  • Refractive Index: n20/D 1.503
  • Solubility: methylene chloride: 0.1?g/mL, clear, colorless
  • Water Partition Coefficient: Reaction
  • Stability/Shelf Life: Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
  • PSA: 24.72000
  • LogP: 3.82570
  • Merck: 3096
  • Sensitiveness: Moisture Sensitive
  • Color/Form: 1.0?M in methylene chloride
  • Solubility: It is easily soluble in dichloromethane, tetrahydrofuran, acetonitrile and N, N-dimethylformamide.
  • Vapor Pressure: 0.0±0.5 mmHg at 25°C

N,N'-Dicyclohexylcarbodiimide Security Information

  • Symbol: GHS02 GHS05 GHS07
  • Prompt：dangerous
  • Signal Word：Danger
  • Hazard Statement： H226,H312,H315,H317,H318
  • Warning Statement： P280,P305+P351+P338
  • Hazardous Material transportation number：UN 2922 8/PG 2
  • WGK Germany：1
  • Hazard Category Code： 22-24-41-43
  • Safety Instruction： S26-S36/37/39-S45-S41-S24-S37/39-S24/25-S36-S16-S53
  • FLUKA BRAND F CODES：3-8-10-21
  • RTECS：FF2160000
  • Hazardous Material Identification： T+
  • HazardClass：6.1
  • PackingGroup：II
  • TSCA：Yes
  • Storage Condition：0-10°C
  • Packing Group：II
  • Hazard Level：6.1
  • Safety Term：6.1
  • Packing Group：II
  • Risk Phrases：R21; R36/38; R41; R43

N,N'-Dicyclohexylcarbodiimide Customs Data

  • HS CODE：29252000
  • Customs Data：

    China Customs Code:

    2921300090

    Overview:

    2921300090 Other rings(Alkane,Alkene,Terpene)Monoamine or polyamine(Including its derivatives and their salts). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

N,N'-Dicyclohexylcarbodiimide Pricemore >>

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N,N'-Dicyclohexylcarbodiimide Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:538-75-0)Dicyclohexylcarbodiimide
Order Number:1637737;sfd21690
Stock Status:in Stock
Quantity:Company Customization/200kg
Purity:98%/99.9%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:538-75-0)二環(huán)己基碳二亞胺
Order Number:LE1637737;LE18702;LE6469
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:30
Price ($):discuss personally

N,N'-Dicyclohexylcarbodiimide Spectrogram

1H NMR 300 MHz DMSO
1H NMR
GC-MS
GC-MS
13C NMR
13C NMR

N,N'-Dicyclohexylcarbodiimide Related Literature

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Suzhou Senfeida Chemical Co., Ltd
(CAS:538-75-0)Dicyclohexylcarbodiimide
1637737;sfd21690
Purity:98%/99.9%
Quantity:Company Customization/200kg
Price ($):Inquiry/Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:538-75-0)二環(huán)己基碳二亞胺
LE1637737;LE18702;LE6469
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
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