Cas no 533-45-9 (clomethiazole)
clomethiazole Chemical and Physical Properties
Names and Identifiers
-
- clomethiazole
- chlormethiazole
- 5-(2-chloroethyl)-4-methylthiazole
- 5-(2-chloroethyl)-4-methyl-1,3-thiazole
- Clomethiazolum
- Chlormethiazol
- Clomethiazol
- Clometiazole
- Distraneurin
- Emineurina
- CLOMETHIAZOLE [MI]
- BRD-K50422030-001-01-2
- Somnevrin
- MLS004754487
- SMR002529479
- NCGC00024842-02
- DB06470
- Tocris-0881
- NCGC00024842-05
- Clometiazolo
- Chlorethiazole
- UNII-0C5DBZ19HV
- Tox21_110931
- BRN 0114244
- EINECS 208-565-7
- 4-Methyl-5-(beta-chloroethyl)thiazole
- D07330
- 5-(2-Chloroethyl)-4-methyl-1,3-thiazole #
- Chloro-S.C.T.Z.
- Clometiazol [INN-Spanish]
- Clomethiazole (INN)
- Distraneurine
- HY-129105
- Clometiazol
- NCGC00024842-01
- WY 1485
- NCGC00024842-04
- 4-27-00-00990 (Beilstein Handbook Reference)
- FT-0659713
- 0C5DBZ19HV
- CHEMBL315795
- MFCD00868012
- CLOMETHIAZOLE [WHO-DD]
- 5-(2-Chloro-ethyl)-4-methyl-thiazole
- Q417178
- SY101781
- AKOS011348416
- SCTZ [as edisylate]
- Clomethiazolum [INN-Latin]
- Clomethiazole [INN:BAN]
- Clometiazolo [DCIT]
- Distraneurine (TN)
- Z945806150
- Chloraethiazol
- BPBio1_000815
- NS00007179
- C6H8ClNS
- Thiazole, 5-(2-chloroethyl)-4-methyl-
- DTXSID6022842
- Heminevrin (Salt/Mix)
- BDBM234400
- W-203012
- EN300-60459
- CLOMETHIAZOLE [NFLIS-DRUG]
- BRD-K50422030-003-01-8
- SCHEMBL35223
- Chlorethiazol
- AB07565
- Tox21_110931_1
- SDCCGSBI-0633688.P001
- Biomol-NT_000260
- Clomethiazole [INN]
- 4-Methyl-5-(.beta.-chloroethyl)thiazole
- DTXCID802842
- CHEBI:92875
- CAS-533-45-9
- CLOMETHIAZOLE [MART.]
- SCTZ (Salt/Mix)
- CS-0103601
- 4-methyl-5-(2-chloroethyl)-thiazole
- NCGC00024842-03
- AS-13864
- AC-33175
- 533-45-9
- BRD-K50422030-001-05-3
- DB-071667
- BRD-K50422030-003-02-6
- CLOMETHIAZOLE (MART.)
- clomAtiazole
- N05CM02
- 208-565-7
- Clometiazol (INN-Spanish)
- SCTZ (AS EDISYLATE)
- FC16096
- CLOMETHIAZOLE (NFLIS-DRUG)
- Clomethiazolum (INN-Latin)
-
- MDL： MFCD00868012
- Inchi： 1S/C6H8ClNS/c1-5-6(2-3-7)9-4-8-5/h4H,2-3H2,1H3
- InChI Key： PCLITLDOTJTVDJ-UHFFFAOYSA-N
- SMILES： ClCCC1=C(C)N=CS1
Computed Properties
- Exact Mass: 196.98300
- Monoisotopic Mass: 161.006598
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 9
- Rotatable Bond Count: 2
- Complexity: 89.1
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.1
- Topological Polar Surface Area: 41.1
Experimental Properties
- Color/Form: No data avaiable
- Density: d425 1.233
- Melting Point: 133-137 °C
- Boiling Point: 245.8°C at 760 mmHg
- Flash Point: 102.4 °C
- Refractive Index: 1.6000 (estimate)
- PSA: 41.13000
- LogP: 3.03480
- Vapor Pressure: No data available
clomethiazole Security Information
- Signal Word：Danger
- Hazard Statement： H302; H317; H318
- Warning Statement： P261; P264; P270; P272; P280; P301+P312; P302+P352; P305+P351+P338; P310; P321; P330; P333+P313; P363; P501
- Safety Instruction： H302 (100%) H315 (20%) H319 (80%)
- Storage Condition：Store at room temperature
clomethiazole Customs Data
- HS CODE：2934100090
- Customs Data：
China Customs Code:
2934100090Overview:
2934100090. Compounds that structurally contain a non fused thiazole ring(Whether hydrogenated or not). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
clomethiazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 049113-1g |
5-(2-Chloroethyl)-4-methylthiazole |
533-45-9 | 97% | 1g |
￡141.00 | 2022-03-01 | |
| Fluorochem | 049113-5g |
5-(2-Chloroethyl)-4-methylthiazole |
533-45-9 | 97% | 5g |
￡422.00 | 2022-03-01 | |
| AstaTech | 30040-1/G |
5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE |
533-45-9 | 97% | 1g |
$89 | 2023-09-18 | |
| AstaTech | 30040-5/G |
5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE |
533-45-9 | 97% | 5g |
$257 | 2023-09-18 | |
| ChemScence | CS-0103601-100mg |
Clomethiazole |
533-45-9 | 98.19% | 100mg |
$50.0 | 2022-04-27 | |
| TRC | C587020-100mg |
Clomethiazolum |
533-45-9 | 100mg |
$ 127.00 | 2023-09-08 | ||
| TRC | C587020-1g |
Clomethiazolum |
533-45-9 | 1g |
$425.00 | 2023-05-18 | ||
| TRC | C587020-2g |
Clomethiazolum |
533-45-9 | 2g |
$509.00 | 2023-05-18 | ||
| TRC | C587020-5g |
Clomethiazolum |
533-45-9 | 5g |
$764.00 | 2023-05-18 | ||
| TRC | C587020-10g |
Clomethiazolum |
533-45-9 | 10g |
$984.00 | 2023-05-18 |
clomethiazole Related Literature
-
Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
-
Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
-
Robert P. Davies,Maria A. Giménez,Laura Patel,Andrew J. P. White Dalton Trans., 2008, 5705-5707
-
Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
Additional information on clomethiazole
Understanding Clomethiazole (CAS No. 533-45-9): A Comprehensive Overview
Clomethiazole (CAS No. 533-45-9), also known as Chlormethiazole, is a chemical compound with significant pharmacological properties. This thiazole derivative has been studied extensively for its sedative, hypnotic, and anticonvulsant effects. The compound's unique structure and mechanism of action make it a subject of interest in both clinical and research settings. In this article, we delve into the properties, applications, and current trends surrounding Clomethiazole, addressing common queries and highlighting its relevance in modern medicine.
The chemical name for Clomethiazole is 5-(2-chloroethyl)-4-methylthiazole, and its molecular formula is C6H8ClNS. With a molecular weight of 161.65 g/mol, this compound is characterized by its thiazole ring, which plays a crucial role in its biological activity. Researchers often explore Clomethiazole for its potential in managing conditions such as insomnia, anxiety, and alcohol withdrawal syndrome. Its ability to modulate GABA receptors in the central nervous system has been a focal point of numerous studies.
One of the most frequently asked questions about Clomethiazole is its safety profile and side effects. While the compound has demonstrated efficacy in certain therapeutic areas, it is essential to consider its pharmacokinetics and potential interactions with other medications. For instance, Clomethiazole is metabolized primarily in the liver, and its elimination half-life can vary depending on individual factors. Patients and healthcare providers often search for information on Clomethiazole dosage, Clomethiazole side effects, and Clomethiazole interactions to ensure safe usage.
In recent years, the interest in Clomethiazole has extended beyond its traditional applications. With the growing focus on mental health and neurological disorders, researchers are investigating its potential in treating conditions like epilepsy and neuropathic pain. Additionally, the compound's mechanism of action has sparked curiosity in the field of neuropharmacology, where scientists aim to develop newer, more effective analogs. Searches for Clomethiazole research and Clomethiazole mechanism of action have seen a notable increase, reflecting this trend.
Another area of interest is the synthesis and formulation of Clomethiazole. Pharmaceutical companies and chemists often look for optimized methods to produce this compound with high purity and yield. The CAS No. 533-45-9 serves as a unique identifier in chemical databases, facilitating research and regulatory compliance. Queries such as Clomethiazole synthesis and Clomethiazole suppliers are common among professionals in the field.
From a regulatory standpoint, Clomethiazole is approved for use in certain countries under strict guidelines. Its classification and legal status vary by region, making it crucial for stakeholders to stay informed about local regulations. Terms like Clomethiazole prescription and Clomethiazole availability are often searched by healthcare providers and patients alike.
In conclusion, Clomethiazole (CAS No. 533-45-9) remains a compound of significant scientific and medical interest. Its diverse applications, coupled with ongoing research, ensure its continued relevance in pharmacology. Whether you are a researcher, healthcare professional, or simply curious about this compound, understanding its properties and potential is essential. By addressing common questions and trends, this article aims to provide a thorough and up-to-date resource on Clomethiazole.
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