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Comprehensive Guide to 11a-Hydroxy-18-methylestr-4-ene-3,17-dione (CAS No. 53067-82-6): Properties, Applications, and Market Insights

11a-Hydroxy-18-methylestr-4-ene-3,17-dione (CAS No. 53067-82-6) is a specialized steroidal compound that has garnered significant attention in pharmaceutical and biochemical research. This compound, often referred to by its abbreviated name 11a-Hydroxy-18-methyl-4-ene-3,17-dione, plays a crucial role in the synthesis of various steroidal drugs and intermediates. Its unique structural features, including the 11a-hydroxy and 18-methyl groups, make it a valuable building block in organic chemistry and drug development.

The molecular formula of 11a-Hydroxy-18-methylestr-4-ene-3,17-dione is C20H28O3, with a molecular weight of 316.44 g/mol. Its IUPAC name is (8R,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. The compound's steroidal backbone and functional groups contribute to its reactivity and utility in synthetic applications.

One of the most searched questions about this compound is: "What is 11a-Hydroxy-18-methylestr-4-ene-3,17-dione used for?" The primary applications of this compound lie in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of corticosteroids and other steroidal hormones. Researchers are particularly interested in its potential for developing novel anti-inflammatory agents, given the growing demand for safer and more effective treatments in this therapeutic area.

Recent advancements in steroid chemistry have highlighted the importance of 11a-Hydroxy-18-methyl-4-ene-3,17-dione derivatives in drug discovery. The compound's ability to undergo selective modifications at various positions makes it a versatile starting material for creating analogs with improved pharmacological properties. This aligns with current trends in personalized medicine and targeted drug delivery, which are among the most searched topics in pharmaceutical research today.

The synthesis of 11a-Hydroxy-18-methylestr-4-ene-3,17-dione typically involves microbial transformation or chemical modification of steroidal precursors. Many researchers search for information about "11a-Hydroxy-18-methylestr-4-ene-3,17-dione synthesis methods", as optimization of these processes is crucial for industrial-scale production. Recent studies have focused on developing more efficient and environmentally friendly synthetic routes, reflecting the growing emphasis on green chemistry in the pharmaceutical sector.

From a market perspective, the demand for steroid intermediates like 11a-Hydroxy-18-methyl-4-ene-3,17-dione continues to grow, driven by the expanding global pharmaceutical industry. Analysts frequently search for "11a-Hydroxy-18-methylestr-4-ene-3,17-dione market trends" to understand pricing fluctuations and supply chain dynamics. The compound's niche applications in research and drug development contribute to its stable market position, with Asia emerging as a significant production hub.

Quality control is another important aspect frequently searched by users, with queries like "11a-Hydroxy-18-methylestr-4-ene-3,17-dione purity standards" being common. The compound is typically characterized using advanced analytical techniques such as HPLC, NMR, and mass spectrometry to ensure compliance with pharmaceutical-grade specifications. These quality assurance measures are particularly important given the compound's use in drug synthesis.

In research settings, 11a-Hydroxy-18-methylestr-4-ene-3,17-dione has shown promise in various biochemical studies. Scientists are investigating its potential interactions with steroid receptors and enzymes, which could lead to new therapeutic applications. This aligns with current interests in steroid receptor modulators and enzyme inhibitors, which are hot topics in medicinal chemistry research.

Storage and handling of 11a-Hydroxy-18-methyl-4-ene-3,17-dione require standard laboratory precautions. Many users search for information about "11a-Hydroxy-18-methylestr-4-ene-3,17-dione stability" and proper storage conditions. The compound should be kept in a cool, dry place, protected from light and moisture to maintain its chemical integrity over time.

The future outlook for 11a-Hydroxy-18-methylestr-4-ene-3,17-dione appears promising, with ongoing research exploring its potential in various therapeutic areas. As the pharmaceutical industry continues to evolve, this compound is likely to maintain its importance as a versatile intermediate in steroid synthesis. Researchers and manufacturers alike will continue to monitor developments in this field, particularly as they relate to steroid drug discovery and process optimization.

For those interested in sourcing 11a-Hydroxy-18-methyl-4-ene-3,17-dione, it's important to work with reputable suppliers who can provide proper documentation and quality assurance. Common search terms include "11a-Hydroxy-18-methylestr-4-ene-3,17-dione suppliers" and "CAS 53067-82-6 manufacturers", reflecting the practical needs of researchers and pharmaceutical companies working with this compound.

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