Cas no 471-53-4 (Glycyrrhetinic Acid)

Glycyrrhetinic Acid is a naturally occurring triterpenoid compound derived from licorice root extract. It exhibits potent anti-inflammatory and anti-allergic properties, making it suitable for applications in skincare formulations requiring enhanced soothing and protective effects against irritation and sensitivity. Its stability and bioavailability contribute to its widespread use in cosmetic and pharmaceutical industries.
Glycyrrhetinic Acid structure
Glycyrrhetinic Acid structure
Product Name:Glycyrrhetinic Acid
CAS No:471-53-4
MF:C30H46O4
MW:470.683849811554
MDL:MFCD00003706
CID:37616
PubChem ID:24895033
Update Time:2025-09-22

Glycyrrhetinic Acid Chemical and Physical Properties

Names and Identifiers

    • Enoxolone
    • 18-BETA-GLYCYRRHETINIC ACID
    • 18B-GLYCYRRHETINIC ACID
    • (2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDRO-PICENE-2-CARBOXYLIC
    • ACID
    • (3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
    • 3BETA-HYDROXY-11-OXO-18BETA, 20BETA-OLEAN-12-EN-29-OIC ACID
    • 3BETA-HYDROXY-11-OXO-18BETA-OLEAN-12-EN-30-OIC ACID
    • 3b-hydroxy-11-oxo-18b,20b-olean-12-en-29-oic acid
    • 3B-HYDROXY-11-OXO-18B-OLEAN-12-EN-30-OIC ACID
    • B-GLYCYRRHETINIC ACID
    • B-GLYCYRRNETINIC ACID
    • ENOLOXONE
    • GLYCYRRHETIC ACID
    • GLYCYRRHETINIC ACID
    • GLYCYRRHETINIC ACID, 18B-
    • URALENIC ACID
    • 18-beta-glycyrrheticacid
    • 3.beta.-Hydroxy-11-oxo-12-oleanen-30-oicacid
    • 3-beta-hydroxy-11-oxo-olean-12-en-30-oicaci
    • 3-beta-hydroxy-11-oxoolean-12-en-30-oicacid
    • 18β-Glycyrrhetinic acid
    • 18b-Glycyrrhetic acid
    • GLYCYRRHETINIC ACID, 18B-(P) PrintBack
    • GLYCYRRHETINIC ACID, 18B-(SH) PrintBack
    • β-Glycyrrhetinic Acid
    • Arthrodont
    • biosone
    • glycyrrhetin
    • GM 1658
    • PO 12
    • STX 352
    • Glycyrrhetintic Acid
    • 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid
    • Subglycyrrhelinic acid
    • 471-53-4
    • 18beta-glycyrrhetic acid
    • Glycyrrhitinic acid
    • 3-Hydroxy-11-oxo-12-oleanen-29-oic acid; 3β-form
    • 18-Isoglycyrrhetinic acid
    • 18-alpha-Glycyrrhetins?ure
    • 18?-Glycyrrhetic acid
    • 18-b-GLYCYRRHETINIC ACID
    • 3-Hydroxy-11-oxo-12-oleanen-30-oic acid; (3β,18α)-form
    • [471-53-4]
    • 3-Hydroxy-11-oxo-12-oleanen-30-oic acid; (3β,18β)-form
    • ENOXOLONE (EP MONOGRAPH)
    • SMR000058239
    • SCHEMBL18540
    • Enoxolona [INN-Spanish]
    • NCGC00181115-01
    • AC-8906
    • NSC-35347
    • GlycyrrhetinicAcid
    • CHEBI:30853
    • AC-1925
    • Q5948038
    • NCGC00017244-20
    • NCGC00017244-06
    • UNII-P540XA09DR
    • Enoxolone, Glycyrrhetinic acid
    • BDBM50233538
    • DTXSID9020669
    • D03AX10
    • (3beta,20beta)-3-Hydroxy-11-oxo-olean-12-en-29-oic acid
    • A-Glycyrrhetinic acid
    • Q-201057
    • Enoxolone (INN)
    • SR-01000721867-5
    • BRD-K96137854-001-17-1
    • NCGC00017244-04
    • CAS-471-53-4
    • SR-01000721867-6
    • HY-N0180
    • 18beta-Glycyrrhetinic acid, 97%
    • Acid, Rhetinic
    • 3beta-Hydroxy-11-oxo-18beta,20beta-olean-12-en-29-oic acid
    • Opera_ID_1048
    • Hidermart
    • Tox21_110804
    • 18-Glycyrrhetinic acid
    • NCGC00017244-03
    • Enoxolone (synonym: 18ss--Glycyrrhetinic acid)
    • SR-01000721867-4
    • Glycyrrhetinate
    • DTXCID50669
    • 18beta-Glycyrrhetinic acid
    • 18 beta -Glycyrrhetinic Acid
    • (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
    • NCGC00142473-03
    • Glycyrrhetinic acid [JAN]
    • ENOXOLONE [EP MONOGRAPH]
    • Glyciram
    • NS00000590
    • beta-Glycyrrhetinic acid
    • ENOXOLONE (MART.)
    • AKOS015960428
    • KS-1262
    • 18beta-Glycyrrhetinic acid, purum, >=97.0% (T)
    • DB13089
    • Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-
    • Acid, Glycyrrhetic
    • Acid, Glycyrrhetinic
    • Enoxolonum
    • (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylicacid
    • CCG-208506
    • S00284
    • Tox21_200799
    • Acid, Uralenic
    • (3beta,5beta,14beta)-3-Hydroxy-11-Oxoolean-12-En-29-Oic Acid
    • SR-01000721867-3
    • 18-beta-Glycyrrhetic acid
    • BRN 2229654
    • ENOXOLONE (EP IMPURITY)
    • GM-1658
    • Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo-
    • Glycyrrhetin ;18beta Glycyrrhetinic acid
    • CS-W020624
    • (3beta)-3-hydroxy-11-oxoolean-12-en-30-oic acid
    • s2296
    • ENOXOLONE [INN]
    • 18 beta-Glycyrrhetintic Acid
    • Rhetinic Acid
    • 4-10-00-03775 (Beilstein Handbook Reference)
    • SR-01000721867
    • ENOXOLONE [MI]
    • LMPR0106150014
    • 3beta-Hydroxy-11-oxoolean-12-en-30-oic acid
    • Jintan
    • CHEMBL230006
    • (5S,8S,15S,18S,1R,2R,10R,14R,20R)-18-hydroxy-1,2,5,8,15,19,19-heptamethyl-13-o xopentacyclo[12.8.0.0<2,11>.0<5,10>.0<15,20>]docos-11-ene-8-carboxylic acid
    • Enoxolonum [INN-Latin]
    • CBW
    • HMDB: 0011628
    • G0149
    • (3beta,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
    • alpha-Glycyrrhetinic acid
    • CCRIS 3962
    • 1ST40366
    • NSC 35347
    • Enoxolone (Glycyrrhetinic acid)
    • Tox21_112726
    • Enoxolona
    • HMS2233P23
    • (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
    • 3ss-Hydroxy-11-oxo-18ss,20ss-olean-12-en-29-oic acid
    • MPDGHEJMBKOTSU-YKLVYJNSSA-N
    • MLS000028748
    • P540XA09DR
    • NSC-35350
    • Enoxolone 100 microg/mL in Acetonitrile
    • CHEBI: 30853
    • 107420-91-7
    • Enoxolone, European Pharmacopoeia (EP) Reference Standard
    • 3-beta-Hydroxy-11-oxoolean-12-en-30-oic acid
    • 3-Glycyrrhetinic acid
    • Enoxolone [INN:BAN:DCF]
    • NCGC00258353-01
    • Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3beta,20beta)-
    • D00156
    • Enoxolone; 18beta-Glycyrrhetinic acid; 3?-Hydroxy-11-oxo-18?,20?-olean-12-en-29-oic acid
    • Enoxolone (Glycyrrhetin)
    • 1449-05-4
    • STX-352
    • MFCD00003706
    • ENOXOLONE [MART.]
    • MLS001146949
    • Glycyrrhetinic acid (JAN)
    • GTPL11264
    • 3beta-hydroxy-11-oxoolean-12-en-29-oic acid
    • BX-1
    • ENOXOLONE [WHO-DD]
    • EINECS 207-444-6
    • 18
    • AKOS016036757
    • ENOXOLONE [EP IMPURITY]
    • NCGC00017244-16
    • C02283
    • Hidermart (TN)
    • 15301-63-0
    • MLS002207101
    • A-Glycyrrhetinic acid (Standard)
    • FG09301
    • HY-N0180R
    • 207-444-6
    • 3-b-Hydroxy-11-oxo-18b,20b-olean-12-en-29-oic acid;Enoxolone
    • Glycyrrhetinic Acid
    • MDL： MFCD00003706
    • Inchi： 1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21?,22-,23?,26+,27-,28-,29+,30+/m0/s1
    • InChI Key： MPDGHEJMBKOTSU-VOPRYAMFSA-N
    • SMILES： O[C@H]1CC[C@@]2(C)C(C1(C)C)CC[C@@]1(C)[C@]3(C)CC[C@@]4(C)CC[C@@](C(=O)O)(C)C[C@H]4C3=CC(C12)=O
    • BRN： 2229654

Computed Properties

  • Exact Mass: 470.34000
  • Monoisotopic Mass: 470.33960994 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 34
  • Rotatable Bond Count: 1
  • Complexity: 965
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 9
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 5
  • XLogP3: 6.4
  • Molecular Weight: 470.7
  • Topological Polar Surface Area: 74.6?2

Experimental Properties

  • Color/Form: Powder
  • Density: 0.9967 (rough estimate)
  • Melting Point: 292-295?°C (lit.)
  • Boiling Point: 588.3°C at 760 mmHg
  • Refractive Index: 162 ° (C=1, MeOH)
  • Water Partition Coefficient: Dissolve in acetic acid
  • PSA: 74.60000
  • LogP: 6.41260
  • Merck: 3590
  • Specific Rotation: 165 o (c=1, CHCl3,on dry ba)
  • FEMA: 2465
  • Optical Activity: [α]22/D +170.0°, c =?1 in chloroform
  • Solubility: Insoluble in water, soluble in ethanol, chloroform, pyridine, acetic acid.

Glycyrrhetinic Acid Security Information

  • Symbol: GHS07
  • Signal Word：Warning
  • Hazard Statement： H302,H319
  • Warning Statement： P305+P351+P338
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Hazard Category Code： 22-36
  • Safety Instruction： S22; S24/25
  • RTECS：RK0180000
  • Hazardous Material Identification： Xn
  • Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
  • Safety Term：S22;S24/25
  • Risk Phrases：R22; R36

Glycyrrhetinic Acid Customs Data

  • HS CODE：2938909030
  • Customs Data：

    China Customs Code:

    2918990090

    Overview:

    2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Glycyrrhetinic Acid Pricemore >>

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Glycyrrhetinic Acid Suppliers

Amadis Chemical Company Limited
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(CAS:471-53-4)Glycyrrhetinic Acid
Order Number:A827163
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:25
Price ($):220.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
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(CAS:471-53-4)18 β-glycyrrhetintic acid
Order Number:LE10452;LE2468682;LE6548
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:471-53-4)18β-Glycyrrhetinic Acid
Order Number:sfd19212
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Hubei Cuiyuan Biotechnology Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:471-53-4)Glycyrrhetinicacid
Order Number:CRN0822
Stock Status:in stock
Quantity:5mg/20mg/50mg
Purity:≥98%
Pricing Information Last Updated:Friday, 14 March 2025 10:55
Price ($):

Glycyrrhetinic Acid Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Glycyrrhetinic Acid Related Literature

Related Categories

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Amadis Chemical Company Limited
(CAS:471-53-4)Glycyrrhetinic Acid
A827163
Purity:99%
Quantity:100g
Price ($):220.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:471-53-4)18 β-glycyrrhetintic acid
LE10452;LE2468682;LE6548
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
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