Cas no 5267-46-9 ((4-Methoxyphenyl)(phenyl)methanamine Hydrochloride)

4-Methoxyphenyl)(phenyl)methanamine Hydrochloride is a hydrochloride salt derivative of a substituted methanamine, characterized by its methoxyphenyl and phenyl functional groups. This compound is primarily utilized in organic synthesis and pharmaceutical research, where it serves as a key intermediate for the development of bioactive molecules. Its crystalline form ensures stability and ease of handling, while the hydrochloride salt enhances solubility in polar solvents, facilitating reactions in aqueous or protic media. The presence of electron-donating methoxy and aromatic groups makes it a versatile building block for constructing complex structures, particularly in medicinal chemistry applications. Proper storage under anhydrous conditions is recommended to maintain its integrity.
(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride structure
5267-46-9 structure
Product Name:(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride
CAS No:5267-46-9
MF:C14H16ClNO
MW:249.735942840576
MDL:MFCD00235188
CID:937287
PubChem ID:43831540
Update Time:2025-11-01

(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • C-(4-METHOXY-PHENYL)-C-PHENYL-METHYL-AMMONIUM CHLORIDE
    • AKOS AU36-M298
    • AKOS BC-1789
    • Albb-004681
    • C -(4-METHOXY-PHENYL)- C -PHENYL-METHYL-AMMONIUM
    • C-(4-METHOXY-PHENYL)-C-PHENYL-METHYLAMINE HYDROCHLORIDE
    • CHLORIDE
    • C-(4-METHOXY-PHENYL)-C-PHENYL-METHYL-AMMONIUMCHLORIDE
    • (4-methoxyphenyl)(phenyl)methanamine hydrochloride
    • 5267-46-9
    • (4-Methoxyphenyl)(phenyl)methanamine HCl
    • CS-0150416
    • MFCD00235188
    • (4-methoxyphenyl)-phenylmethanamine;hydrochloride
    • N12581
    • AS-68562
    • EN300-298531
    • 1-(4-METHOXYPHENYL)-1-PHENYLMETHANAMINE HYDROCHLORIDE
    • (4-methoxyphenyl)(phenyl)methylamine
    • AKOS004118281
    • (4-methoxyphenyl)-phenylmethanamine hydrochloride
    • (4-Methoxyphenyl)(phenyl)methylamine hydrochloride
    • (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride
    • MDL: MFCD00235188
    • Inchi: 1S/C14H15NO.ClH/c1-16-13-9-7-12(8-10-13)14(15)11-5-3-2-4-6-11;/h2-10,14H,15H2,1H3;1H
    • InChI Key: NCSHDWNETPLWIU-UHFFFAOYSA-N
    • SMILES: Cl.O(C)C1C=CC(=CC=1)C(C1C=CC=CC=1)N

Computed Properties

  • Exact Mass: 249.09200
  • Monoisotopic Mass: 249.0920418g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 3
  • Complexity: 193
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 35.2?2

Experimental Properties

  • PSA: 35.25000
  • LogP: 4.24560

(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride Customs Data

  • HS CODE:2922299090
  • Customs Data:

    China Customs Code:

    2922299090

    Overview:

    2922299090. Other amino groups(naphthol\phenol)And ether\Esters [including their salts, Except those containing more than one oxygen-containing group]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Summary:

    2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride Pricemore >>

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Additional information on (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride

Introduction to (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride (CAS No. 5267-46-9)

(4-Methoxyphenyl)(phenyl)methanamine Hydrochloride, chemically known as N-(4-methoxyphenyl)-benzylamine hydrochloride, is a significant compound in the field of pharmaceutical chemistry. With a CAS number of 5267-46-9, this compound has garnered attention due to its potential applications in drug development and medicinal research. The molecular structure of this compound features a benzylamine moiety attached to a 4-methoxyphenyl group, which contributes to its unique chemical properties and reactivity.

The synthesis of (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride involves meticulous chemical processes that ensure high purity and yield. The hydrochloride salt form enhances the stability and solubility of the compound, making it more suitable for various pharmaceutical applications. This compound's versatility stems from its ability to participate in multiple chemical reactions, including nucleophilic substitutions and condensation reactions, which are pivotal in the synthesis of more complex molecules.

In recent years, (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride has been explored for its pharmacological properties. Studies have indicated that this compound may exhibit significant biological activity, particularly in the realm of central nervous system (CNS) disorders. The presence of the 4-methoxyphenyl group suggests potential interactions with certain neurotransmitter receptors, which could be leveraged in the development of novel therapeutic agents. Furthermore, research has hinted at its potential role in modulating enzyme activities associated with neurodegenerative diseases.

One of the most compelling aspects of (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride is its role as a building block in the synthesis of more complex pharmacophores. Pharmaceutical researchers have utilized this compound to develop novel derivatives with enhanced pharmacological profiles. For instance, modifications to the benzylamine moiety have led to compounds with improved binding affinities and selectivity for specific targets. These derivatives are being evaluated in preclinical studies to assess their efficacy and safety profiles.

The chemical properties of (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride also make it a valuable intermediate in organic synthesis. Its ability to undergo various transformations allows chemists to construct intricate molecular architectures efficiently. This has opened up new avenues for the development of synthetic methodologies that are both efficient and environmentally friendly. The compound's stability under different reaction conditions further enhances its utility as a synthetic intermediate.

Recent advancements in computational chemistry have also contributed to a deeper understanding of (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride's behavior. Molecular modeling studies have provided insights into its interactions with biological targets, helping researchers predict potential drug-like properties more accurately. These computational tools are particularly valuable in virtual screening campaigns, where large libraries of compounds are rapidly evaluated for their binding affinity and selectivity.

The pharmaceutical industry continues to invest heavily in research aimed at uncovering new therapeutic applications for (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride. Ongoing clinical trials are assessing its efficacy in treating various conditions, including cognitive disorders and neuroinflammatory diseases. The results from these trials are expected to provide further validation for the compound's potential as a lead molecule in drug discovery.

Moreover, the environmental impact of synthesizing (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride has been a focus of recent research. Efforts are underway to develop greener synthetic routes that minimize waste and reduce energy consumption. These initiatives align with broader trends in sustainable chemistry, where the goal is to develop processes that are both economically viable and environmentally responsible.

In conclusion, (4-Methoxyphenyl)(phenyl)methanamine Hydrochloride is a multifaceted compound with significant potential in pharmaceutical research and drug development. Its unique chemical properties, coupled with its role as a building block for more complex molecules, make it a valuable asset in medicinal chemistry. As research continues to uncover new applications and synthetic methodologies, this compound is poised to play an increasingly important role in the future of healthcare.

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