Cas no 526-43-2 (Hydroxyevodiamine)

Hydroxyevodiamine is a bioactive alkaloid derived from Evodia rutaecarpa, a plant traditionally used in herbal medicine. This compound exhibits notable pharmacological properties, including anti-inflammatory, anticancer, and neuroprotective effects. Its mechanism of action involves modulation of key signaling pathways, such as NF-κB and MAPK, contributing to its potential therapeutic applications. Hydroxyevodiamine is characterized by its high purity and stability, making it suitable for research in drug development and molecular biology. Its ability to cross the blood-brain barrier further enhances its relevance in neurological studies. The compound is typically supplied as a white to off-white powder, soluble in organic solvents, and stored under controlled conditions to ensure longevity.
Hydroxyevodiamine structure
Hydroxyevodiamine structure
Product Name:Hydroxyevodiamine
CAS No:526-43-2
MF:C19H17N3O2
MW:319.357184171677
CID:937238
PubChem ID:99652
Update Time:2025-11-02

Hydroxyevodiamine Chemical and Physical Properties

Names and Identifiers

    • Hydroxyevodiamine
    • Rhetsinine
    • 2-[2-(methylamino)benzoyl]-4,9-dihydro-3H-pyrido[3,4-b]indol-1-one
    • 2-[2-(methylamino)benzoyl]-2,3,4,9-tetrahydro-1h-
    • A-carbolin-1-one
    • Spectrum3_001649
    • NSC-258315
    • KBio3_002597
    • SCHEMBL14478778
    • SpecPlus_000722
    • SR-05000002580
    • NSC 258315
    • KBio2_004600
    • 1H-Pyrido[3, 2,3,4,9-tetrahydro-2-[2-(methylamino)benzoyl]-
    • BDBM50292374
    • KBioGR_002453
    • CCG-38771
    • KBioSS_002032
    • 2,3,4,9-Tetrahydro-2-[2-(methylamino)benzoyl]-1H-pyrido[3,4-b]indol-1-one
    • Spectrum2_001661
    • DivK1c_006818
    • Spectrum_001552
    • BRD-K08814982-001-02-9
    • Spectrum5_000548
    • 1H-Pyrido(3,4-b)indol-1-one, 2,3,4,9-tetrahydro-2-(2-(methyamino)benzoyl)-
    • YQ7LSR9JJA
    • CHEMBL508030
    • KBio2_002032
    • KBio2_007168
    • KBio1_001762
    • SPECTRUM1504176
    • BSPBio_003377
    • SR-05000002580-1
    • 2-[2-(Methylamino)benzoyl]-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indol-1-one
    • 526-43-2
    • DTXSID30200576
    • SPBio_001841
    • 2-[2-(Methylamino)benzoyl]-3,4-dihydro-beta-carboline-1(2H)-one
    • Spectrum4_001894
    • NCGC00095696-01
    • 2-(2-(Methylamino)benzoyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one
    • NCGC00095696-02
    • UNII-YQ7LSR9JJA
    • NSC258315
    • Inchi: 1S/C19H17N3O2/c1-20-15-8-4-3-7-14(15)18(23)22-11-10-13-12-6-2-5-9-16(12)21-17(13)19(22)24/h2-9,20-21H,10-11H2,1H3
    • InChI Key: RAEOYMOPVHBBKE-UHFFFAOYSA-N
    • SMILES: O=C1C2=C(C3C=CC=CC=3N2)CCN1C(C1C=CC=CC=1NC)=O

Computed Properties

  • Exact Mass: 319.13200
  • Monoisotopic Mass: 319.132076794g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 2
  • Complexity: 509
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.9
  • Topological Polar Surface Area: 65.2?2

Experimental Properties

  • Density: 1.372±0.06 g/cm3 (20 oC 760 Torr),
  • Solubility: Insuluble (2.5E-3 g/L) (25 oC),
  • PSA: 65.20000
  • LogP: 3.05920

Hydroxyevodiamine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Hydroxyevodiamine Pricemore >>

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526-43-2
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$ 170.00 2022-06-04
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$ 4500.00 2023-09-07
BAI LING WEI Technology Co., Ltd.
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¥54098 2025-08-06

Additional information on Hydroxyevodiamine

Hydroxyevodiamine (CAS 526-43-2): A Comprehensive Overview of Its Properties and Applications

Hydroxyevodiamine (CAS 526-43-2) is a naturally occurring alkaloid derived from the Evodia rutaecarpa plant, a traditional medicinal herb widely used in East Asian medicine. This bioactive compound has garnered significant attention in recent years due to its potential therapeutic properties and diverse applications in modern research. As interest in natural products and plant-derived compounds continues to grow, Hydroxyevodiamine stands out as a promising candidate for various scientific investigations.

The chemical structure of Hydroxyevodiamine features a unique indoloquinazoline skeleton, which contributes to its distinctive biological activities. Researchers have identified this compound as a key active component in Evodia rutaecarpa extracts, responsible for many of the plant's traditional medicinal effects. With the increasing popularity of natural remedies and the search for novel bioactive compounds, Hydroxyevodiamine has become a subject of intense study in pharmacological and biochemical research.

One of the most compelling aspects of Hydroxyevodiamine is its potential role in supporting neurological health. Recent studies suggest that this compound may influence various neurotransmitter systems, making it a potential candidate for research in cognitive function support. As the global population ages and concerns about brain health rise, compounds like Hydroxyevodiamine are receiving increased attention from both the scientific community and health-conscious consumers.

In addition to its neurological applications, Hydroxyevodiamine has shown promise in metabolic research. Preliminary studies indicate that it may influence certain metabolic pathways, which aligns with current scientific interest in metabolic health and weight management solutions. The compound's potential to support healthy metabolism makes it particularly relevant in today's health-conscious society, where natural approaches to wellness are increasingly sought after.

The extraction and purification of Hydroxyevodiamine from Evodia rutaecarpa involve sophisticated techniques that ensure high purity and bioactivity. Advanced methods such as high-performance liquid chromatography (HPLC) and preparative chromatography are commonly employed to isolate this valuable compound. These technological advancements have made Hydroxyevodiamine more accessible for research purposes, contributing to the growing body of knowledge about its properties and potential applications.

Quality control is paramount when working with Hydroxyevodiamine, as the compound's purity directly affects its biological activity. Standard analytical techniques including NMR spectroscopy, mass spectrometry, and HPLC are routinely used to verify the identity and purity of Hydroxyevodiamine preparations. These rigorous quality assurance measures ensure that researchers can rely on consistent material for their investigations into this fascinating natural product.

From a commercial perspective, the market for Hydroxyevodiamine has been steadily growing, driven by increasing research interest and potential applications in various fields. Suppliers specializing in plant-derived compounds have reported rising demand for high-quality Hydroxyevodiamine, particularly from academic institutions and research organizations. This trend reflects the broader movement toward natural product research in the pharmaceutical and nutraceutical industries.

Safety considerations are always important when discussing bioactive compounds like Hydroxyevodiamine. While traditional use of Evodia rutaecarpa suggests a generally favorable safety profile, modern research continues to evaluate the compound's pharmacological characteristics. Current studies focus on understanding its mechanisms of action, potential interactions, and optimal dosage ranges for various applications.

The future of Hydroxyevodiamine research appears promising, with several potential directions emerging. Scientists are particularly interested in exploring its molecular targets and signaling pathways, which could lead to new insights into its biological effects. Additionally, formulation studies are investigating ways to enhance the bioavailability of Hydroxyevodiamine, potentially expanding its range of applications.

For researchers interested in working with Hydroxyevodiamine, it's important to source the compound from reputable suppliers who can provide comprehensive analytical data. Proper storage conditions—typically cool, dry environments protected from light—are essential to maintain the compound's stability over time. These practical considerations ensure that investigations into Hydroxyevodiamine can proceed with high-quality materials.

As the scientific community continues to explore the potential of plant-derived compounds, Hydroxyevodiamine stands out as a particularly interesting subject of study. Its unique chemical structure, diverse biological activities, and traditional medicinal use make it a compelling candidate for further research. Whether investigating its neurological effects, metabolic influences, or other potential applications, Hydroxyevodiamine offers researchers a fascinating natural product with significant scientific promise.

The growing body of research on Hydroxyevodiamine reflects broader trends in natural product chemistry and pharmacology. As consumers and researchers alike seek alternatives to synthetic compounds, naturally derived substances like Hydroxyevodiamine are gaining prominence. This shift aligns with increasing interest in sustainable, plant-based solutions across multiple industries, from healthcare to personal wellness products.

In conclusion, Hydroxyevodiamine (CAS 526-43-2) represents an important area of study in natural product research. Its unique properties, potential health applications, and traditional use make it a valuable subject for scientific investigation. As research techniques continue to advance and interest in plant-derived compounds grows, Hydroxyevodiamine is likely to remain at the forefront of natural product research for years to come.

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