Cas no 518-17-2 (Evodiamine)
Evodiamine is a bioactive indole alkaloid primarily extracted from the dried fruit of Evodia rutaecarpa, a traditional Chinese medicinal herb. It exhibits notable pharmacological properties, including anti-inflammatory, anti-obesity, and anti-cancer activities. Evodiamine functions as a transient receptor potential vanilloid 1 (TRPV1) agonist, contributing to its thermogenic and analgesic effects. Its ability to modulate adipocyte differentiation and apoptosis makes it a candidate for metabolic disorder research. Additionally, evodiamine demonstrates potential in inhibiting tumor cell proliferation by targeting multiple signaling pathways. With high purity and standardized extraction methods, it is widely used in pharmaceutical and nutraceutical research for its versatile biological effects.
Evodiamine structure
Product Name:Evodiamine
CAS No:518-17-2
MF:C19H17N3O
MW:303.357784032822
MDL:MFCD06407824
CID:37955
PubChem ID:442088
Update Time:2025-09-17
Evodiamine Chemical and Physical Properties
Names and Identifiers
-
- EVODIAMINE
- Evodiamine std.
- 8,13,13b,14-Tetrahydro-14-methylindolo[2'3'-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one
- 8,13,13b,14-tetrahydro-14-methyl-,(S)-
- Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- Indol(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (S)-
- Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-
- Evodia rutaecarpa E.P.
- [13bS,(+)]-8,13,13b,14-Tetrahydro-14-methylindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- [13bS,(+)]-8,13,13b,14-Tetrahydro-14-methylindolo[2',3':3,4]pyrido[2,1-b]quinazoline-5(7H)-one
- d-Evodiamine
- (+)-Evodiamine
- EVODIAMINE(P) PrintBack
- Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (13bS)-
- EVODIAMINE PLANT EXTRACT
- [ "(+)-Evodiamine" ]
- SMR001934404
- (S)-14-methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
- Evodiamine, European Pharmacopoeia (EP) Reference Standard
- INDOLO(2',3':3,4)PYRIDO(2,1-B)QUINAZOLIN-5(7H)-ONE, 8,13,13B,14-TETRAHYDRO-14-METHYL-, (13BS)-
- BCP02282
- CS-6161
- C19H17N3O
- VS-12304
- C09187
- CHEMBL463165
- (1S)-21-METHYL-3,13,21-TRIAZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]HENICOSA-2(10),4,6,8,15,17,19-HEPTAEN-14-ONE
- C01825BVNL
- BDBM50560847
- (1S)-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
- AKOS005622478
- MLS006011787
- SCHEMBL682158
- CHEBI:4948
- Q27894193
- HY-N0114
- (S)-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- EVODIAMINE [WHO-DD]
- Indol(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (13bS)-
- DTXSID10966123
- Evodiamine,(S)
- EVODIAMINE [MI]
- Q-100579
- Evodiamine, (+)-
- UNII-C01825BVNL
- 518-17-2
- GLXC-10981
- BBL033833
- MFCD06407824
- STK801981
- (13bS)-14-methyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
- HY-N0114R
- FE09940
- Evodiamine (Standard)
- 637-111-4
- DTXCID401393773
- Evodiamine
-
- MDL： MFCD06407824
- Inchi： 1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1
- InChI Key： TXDUTHBFYKGSAH-SFHVURJKSA-N
- SMILES： O=C1C2C=CC=CC=2N(C)[C@@H]2C3=C(C4C=CC=CC=4N3)CCN21
Computed Properties
- Exact Mass: 303.13700
- Monoisotopic Mass: 303.137162
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 23
- Rotatable Bond Count: 0
- Formal charge: 0
- Complexity: 495
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Functional 3D Acceptor Count: 1
- isomeric RMSD: 0.6
- CID conformational isomer Count: 4
- Topological Polar Surface Area: 39.3
- Molecular Weight: 303.4
- XLogP3: 3.1
- Functional 3D Donor Count: 1
- Functional 3D Cation Count: 2
- Functional 3D ring Count: 5
- Rotatable Bond Count: 0.6
- Surface Charge: 0
- Topological Polar Surface Area: 39.3
Experimental Properties
- Color/Form: Powder
- Density: 1.1684 (rough estimate)
- Melting Point: 278°
- Boiling Point: 444.29°C (rough estimate)
- Flash Point: 575.1 °C at 760 mmHg
- Refractive Index: 1.5900 (estimate)
- Solubility: Soluble in DMSO (5 mg/mL,warm to 40°C), water (<1 mg/mL) at 25 °C, and ethanol (<1 mg/mL) at 25 °C
- PSA: 39.34000
- LogP: 3.31770
- Specific Rotation: D15 +352° (acetone); D +440° (chloroform)
- Solubility: Soluble in acetone, slightly soluble in ethanol, ether, chloroform, almost insoluble in water, petroleum ether, benzene
- Sensitiveness: Sensitive to light
Evodiamine Security Information
-
Symbol:
- Signal Word：Danger
- Hazard Statement： H300
- Warning Statement： P264,P301+P310
- Hazardous Material transportation number：UN 2811 6.1/PG 3
- WGK Germany：3
- Hazard Category Code： 25
- Safety Instruction： S45
-
Hazardous Material Identification：
- Safety Term：S45
- Risk Phrases：R25
- HazardClass：6.1
- PackingGroup：II
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Evodiamine Customs Data
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Evodiamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-N0114-10mM*1mLinDMSO |
Evodiamine |
518-17-2 | 99.59% | 10mM*1mLinDMSO |
￥528 | 2023-07-26 | |
| MedChemExpress | HY-N0114-50mg |
Evodiamine |
518-17-2 | 99.97% | 50mg |
￥350 | 2025-04-16 | |
| MedChemExpress | HY-N0114-100mg |
Evodiamine |
518-17-2 | 99.97% | 100mg |
￥550 | 2025-04-16 | |
| MedChemExpress | HY-N0114-200mg |
Evodiamine |
518-17-2 | 99.59% | 200mg |
￥850 | 2023-07-26 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E101966-20mg |
Evodiamine |
518-17-2 | ,≥99% | 20mg |
￥171.90 | 2023-09-03 | |
| ChemFaces | CFN99993-20mg |
Evodiamine |
518-17-2 | >=98% | 20mg |
$40 | 2021-07-22 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP0266-20mg |
Evodiamine |
518-17-2 | HPLC≥98% | 20mg |
￥100元 | 2023-09-15 | |
| DC Chemicals | DCW-012-20 mg |
Evodiamine |
518-17-2 | >98%, Standard References Grade | 20mg |
$280.0 | 2022-02-28 | |
| S e l l e c k ZHONG GUO | S2382-25mg |
Evodiamine |
518-17-2 | 99.76% | 25mg |
￥647.01 | 2023-09-16 | |
| S e l l e c k ZHONG GUO | S2382-100mg |
Evodiamine |
518-17-2 | 99.76% | 100mg |
￥979.64 | 2023-09-16 |
Evodiamine Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:518-17-2)吳茱萸堿
Order Number:LE8525851;LE10281;LE1059
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:47
Price ($):discuss personally
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:518-17-2)Evodiamine
Order Number:sfd16641
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:37
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:518-17-2)EVODIAMINE
Order Number:A1203676
Stock Status:in Stock
Quantity:100mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:50
Price ($):154.0
Email:[email protected]
Evodiamine Related Literature
-
Huifang Yang,Haoran Guo,Peidong Fan,Xinpan Li,Wenlu Ren,Rui Song Nanoscale, 2020,12, 7024-7034
-
R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
-
M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
-
Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Beta carbolines
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Pyridoindoles Beta carbolines
- Natural Products and Extracts Plant Extracts Plant based Spiranthera odoratissima
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
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Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:518-17-2)吳茱萸堿
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Suzhou Senfeida Chemical Co., Ltd
(CAS:518-17-2)Evodiamine
Purity:99.9%
Quantity:200kg
Price ($):Inquiry