Cas no 5255-33-4 (2-(4-methyl-1,3-thiazol-5-yl)acetic acid)

2-(4-Methyl-1,3-thiazol-5-yl)acetic acid is a heterocyclic carboxylic acid featuring a thiazole core with a methyl substituent at the 4-position and an acetic acid moiety at the 5-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its thiazole ring contributes to enhanced stability and reactivity, making it valuable for constructing biologically active molecules. The acetic acid functional group allows for further derivatization, enabling coupling reactions or salt formation. The product is characterized by high purity and consistent quality, ensuring reliable performance in research and industrial applications. Its structural features make it useful for exploring structure-activity relationships in medicinal chemistry.
2-(4-methyl-1,3-thiazol-5-yl)acetic acid structure
5255-33-4 structure
Product Name:2-(4-methyl-1,3-thiazol-5-yl)acetic acid
CAS No:5255-33-4
MF:C6H7NO2S
MW:157.190280199051
MDL:MFCD01681551
CID:374064
PubChem ID:21326
Update Time:2025-05-21

2-(4-methyl-1,3-thiazol-5-yl)acetic acid Chemical and Physical Properties

Names and Identifiers

    • 2-(4-Methylthiazol-5-yl)acetic acid
    • 2-(4-Methyl-5-thiazolyl)acetic Acid
    • 2-(4-methyl-1,3-thiazol-5-yl)acetic acid
    • 5-Thiazoleacetic acid,4-methyl-
    • 4-Methylthiazol-5-acetic acid
    • 4-Methylthiazol-5-essigsaeure
    • 5-THIAZOLEACETIC ACID,4-METHYL
    • _x000D_2-(4-Methyl-5-thiazolyl)acetic Acid
    • AC-13449
    • MFCD01681551
    • SCHEMBL2208741
    • A870963
    • SY033094
    • CS-0308286
    • CHEBI:185905
    • 4-METHYL-5-THIAZOLEACETICACID
    • AB09733
    • Acide methyl-4 thiazole-acetique-5 [French]
    • EINECS 226-056-8
    • 4-Methyl-5-thiazoleacetic acid
    • EN300-1139372
    • 4-27-00-04018 (Beilstein Handbook Reference)
    • CS-11918
    • 4-methylthiazole-5-acetic-acid
    • AC1428
    • Acide methyl-4 thiazole-acetique-5
    • 5255-33-4
    • AKOS006276495
    • BHYWREOEQYCKSC-UHFFFAOYSA-N
    • FT-0714149
    • (4-Methyl-1,3-thiazol-5-yl)acetic acid #
    • 5-THIAZOLEACETIC ACID, 4-METHYL-
    • 2-(4-Methyl-5-thiazolyl)aceticAcid
    • DTXSID50200538
    • NS00032527
    • BRN 0120919
    • DA-28115
    • DTXCID80123029
    • ?2-(4-Methyl-5-thiazolyl)acetic Acid
    • (4-Methyl-1,3-thiazol-5-yl)acetic acid
    • MDL: MFCD01681551
    • Inchi: 1S/C6H7NO2S/c1-4-5(2-6(8)9)10-3-7-4/h3H,2H2,1H3,(H,8,9)
    • InChI Key: BHYWREOEQYCKSC-UHFFFAOYSA-N
    • SMILES: S1C=NC(C)=C1CC(=O)O

Computed Properties

  • Exact Mass: 157.02000
  • Monoisotopic Mass: 157.01974964g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 140
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 78.4?2

Experimental Properties

  • Boiling Point: 315.1℃/760mmHg
  • PSA: 78.43000
  • LogP: 1.07860

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2-(4-methyl-1,3-thiazol-5-yl)acetic acid Production Method

2-(4-methyl-1,3-thiazol-5-yl)acetic acid Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5255-33-4)2-(4-methyl-1,3-thiazol-5-yl)acetic acid
Order Number:A870963
Stock Status:in Stock
Quantity:100.0mg/250.0mg/500.0mg/1.0g/5.0g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:26
Price ($):191.0/305.0/508.0/762.0/2285.0

Additional information on 2-(4-methyl-1,3-thiazol-5-yl)acetic acid

2-(4-Methyl-1,3-Thiazol-5-yl)Acetic Acid: A Comprehensive Overview

The compound with CAS No. 5255-33-4, commonly referred to as 2-(4-methyl-1,3-thiazol-5-yl)acetic acid, is a fascinating molecule that has garnered significant attention in various fields of chemistry and biology. This compound belongs to the class of thiazole derivatives, which are known for their diverse applications in pharmaceuticals, agrochemicals, and materials science. The thiazole ring at the core of this molecule contributes to its unique chemical properties, making it a subject of interest for researchers exploring novel synthetic pathways and bioactive compounds.

Recent studies have highlighted the potential of 2-(4-methyl-1,3-thiazol-5-yl)acetic acid as a precursor for the synthesis of bioactive molecules. For instance, researchers have utilized this compound to develop antimicrobial agents and anticancer drugs, leveraging its ability to form stable conjugates with other functional groups. The methyl substituent on the thiazole ring plays a crucial role in modulating the compound's reactivity and selectivity during these reactions.

In terms of synthesis, 2-(4-methyl-1,3-thiazol-5-yl)acetic acid can be prepared via a variety of methods, including condensation reactions and oxidative coupling. One notable approach involves the reaction of 4-methylthiazole with acetic acid derivatives under specific catalytic conditions. This method has been optimized in recent studies to improve yield and purity, making it more accessible for large-scale production.

The structural versatility of this compound has also led to its use in the development of sensor materials and catalysts. For example, scientists have incorporated this molecule into polymer matrices to create responsive materials that can detect changes in environmental conditions such as pH or temperature. These applications underscore the importance of understanding the intermolecular interactions and stability of 2-(4-methyl-1,3-thiazol-5-yl)acetic acid under various conditions.

From an environmental perspective, the biodegradability and toxicity of 2-(4-methyl-1,3-thiazol-5-yl)acetic acid have been extensively studied. Research indicates that this compound exhibits low toxicity towards aquatic organisms, making it a safer alternative to traditional chemicals in certain industrial applications. However, further studies are required to fully understand its long-term impact on ecosystems.

In conclusion, 2-(4-methyl-1,3-thiazol-5-yl)acetic acid is a multifaceted compound with promising applications across multiple disciplines. Its unique chemical properties, coupled with recent advancements in synthesis and application techniques, position it as a key player in the development of innovative solutions in science and technology.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:5255-33-4)2-(4-methyl-1,3-thiazol-5-yl)acetic acid
A870963
Purity:99%/99%/99%/99%/99%
Quantity:100.0mg/250.0mg/500.0mg/1.0g/5.0g
Price ($):191.0/305.0/508.0/762.0/2285.0
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