Cas no 52373-72-5 (methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate)

Methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate is a chiral ester derivative commonly employed as a versatile intermediate in organic synthesis and asymmetric catalysis. Its rigid dioxolane ring structure enhances stereochemical stability, making it valuable for the preparation of enantiomerically pure compounds. The (4R) configuration ensures consistent chirality transfer in synthetic routes, particularly in pharmaceutical and fine chemical applications. The ester functionality allows for further derivatization, while the dimethyl substitution on the dioxolane ring improves hydrolytic stability. This compound is often utilized in the synthesis of biologically active molecules, including nucleoside analogs and chiral auxiliaries, due to its reliable reactivity and stereocontrol.
methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate structure
52373-72-5 structure
Product Name:methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
CAS No:52373-72-5
MF:C7H12O4
MW:160.167782783508
MDL:MFCD00066527
CID:367066
PubChem ID:87568984
Update Time:2025-06-08

methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Chemical and Physical Properties

Names and Identifiers

    • Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Methyl Ester
    • (R)-Methyl 2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • (R)-(+)-2,2-dimethyl-1,3-dioxolan-4-carboxylic acid methyl ester
    • 1,3-Dioxolane-4-carboxylicacid, 2,2-dimethyl-, methyl ester, (4R)-
    • methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • Methyl (R)-(+)-2,2,-dimethyl-1,3-dioxolan-4-carboxylate
    • (+)-2,3-O-Isopropylidene-D-glyceric Acid Methyl Ester
    • (+)-Methyl 2,3-O-Isopropylidene-D-glycerate
    • (R)-(+)-2,2-Dimethyl-1,3-dioxolan-4-carboxylate
    • (R)-2,2-Dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester
    • 52373-72-5
    • Methyl(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylate
    • 1,3-Dioxolane-4-carboxylic acid, 2,2-dimethyl-, methyl ester, (4R)-
    • SCHEMBL877770
    • AMY31947
    • (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid methyl ester
    • Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, 98%
    • 1,3-Dioxolane-4-carboxylic acid, 2,2-dimethyl-, methyl ester, (R)-
    • Methyl .alpha.,.beta.-isopropylidene-D-glycerate
    • AKOS015910913
    • AKOS015842237
    • D2562
    • MFCD00066527
    • Methyl (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • DOWWCCDWPKGNGX-RXMQYKEDSA-
    • (R)-2,2-Dimethyl-1,3-dioxolan-4-carboxylic acid methyl ester
    • CS-W008189
    • EN300-7366349
    • (-)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • InChI=1/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m1/s1
    • Methyl 2,3-O-isopropylidene-D-glycerate
    • (R)-methyl2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • J-521715
    • DTXSID00357405
    • AS-15057
    • BCP05163
    • A7683
    • MDL： MFCD00066527
    • Inchi： 1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m1/s1
    • InChI Key： DOWWCCDWPKGNGX-RXMQYKEDSA-N
    • SMILES： O1[C@@H](C(=O)OC)COC1(C)C

Computed Properties

  • Exact Mass: 160.07400
  • Monoisotopic Mass: 160.074
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 164
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.4
  • Topological Polar Surface Area: 44.8A^2

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.106?g/mL?at 25?°C(lit.)
  • Melting Point: No data available
  • Boiling Point: 70-75?°C/10?mmHg(lit.)
  • Flash Point: Fahrenheit: 167 ° f < br / > Celsius: 75 ° C < br / >
  • Refractive Index: n20/D 1.426(lit.)
  • PSA: 44.76000
  • LogP: 0.31090
  • Optical Activity: [α]20/D +8.5°, c =?1.5 in acetone
  • Solubility: Not determined

methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Security Information

  • Prompt：warning
  • Signal Word：Warning
  • Hazard Statement： H227
  • Warning Statement： P210-P280-P403+P235-P501
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Safety Instruction： S23-S24/25
  • FLUKA BRAND F CODES：10-23
  • Safety Term：S23-S24/25
  • Storage Condition：Inert atmosphere,2-8°C

methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Customs Data

  • HS CODE：2932999099
  • Customs Data：

    China Customs Code:

    2932999099

    Overview:

    2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Pricemore >>

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methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Production Method

methyl (4R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:52373-72-5)(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
Order Number:sfd16967
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:37
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:52373-72-5)(R)-(+)-2,2-二甲基-1,3-二氧戊環(huán)-4-羧酸甲酯
Order Number:LE8491234
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:47
Price ($):discuss personally

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Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:52373-72-5)(R)-(+)-2,2-二甲基-1,3-二氧戊環(huán)-4-羧酸甲酯
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