Cas no 117205-81-9 ((4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt)

(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt is a chiral auxiliary and synthetic intermediate widely used in asymmetric synthesis. Its stereochemically defined structure enables precise control in the formation of enantiomerically pure compounds, making it valuable for pharmaceutical and fine chemical applications. The potassium salt form enhances solubility in polar solvents, facilitating its use in aqueous or mixed-phase reactions. The dioxolane ring provides stability under various reaction conditions while remaining cleavable for downstream modifications. This compound is particularly useful in the synthesis of biologically active molecules, where high enantiopurity is critical. Its consistent performance and handling stability make it a reliable choice for complex organic transformations.
(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt structure
117205-81-9 structure
Product Name:(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt
CAS No:117205-81-9
MF:C6H9KO4
MW:184.231563329697
MDL:MFCD27996322
CID:131520
PubChem ID:23678351
Update Time:2025-05-24

(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt Chemical and Physical Properties

Names and Identifiers

    • Potassium (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • (S)-(-)-2, 2 DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLATE
    • (4S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID POTASSIUM SALT
    • 1,3-Dioxolane-4-carboxylicacid, 2,2-dimethyl-, potassium salt (1:1), (4S)-
    • (S)-potassium 2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • potassium (2S)-2,3-isopropylideneglycerate
    • potassium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • potassium 2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • PotassiuM-S-2-diMethyl-1,3-dioxolane-4-carboxylate
    • ZOISWEHAOHFWAH-WCCKRBBISA-M
    • MFCD27996322
    • potassium;(4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • SCHEMBL5789692
    • EN300-1717204
    • Potassium(S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
    • CS-0441635
    • 117205-81-9
    • 1,3-Dioxolane-4-carboxylic acid, 2,2-dimethyl-, potassium salt (1:1), (4S)-
    • AKOS022189135
    • DB-310017
    • (S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt; (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt;
    • (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt
    • MDL: MFCD27996322
    • Inchi: 1S/C6H10O4.K/c1-6(2)9-3-4(10-6)5(7)8;/h4H,3H2,1-2H3,(H,7,8);/q;+1/p-1/t4-;/m0./s1
    • InChI Key: ZOISWEHAOHFWAH-WCCKRBBISA-M
    • SMILES: [K+].O1[C@H](C(=O)[O-])COC1(C)C

Computed Properties

  • Exact Mass: 145.05000
  • Monoisotopic Mass: 184.01379025g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 157
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 58.6?2

Experimental Properties

  • Melting Point: NA
  • PSA: 58.59000
  • LogP: -1.11220

(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt Security Information

(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt Customs Data

  • HS CODE:2932999099
  • Customs Data:

    China Customs Code:

    2932999099

    Overview:

    2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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(4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt Related Literature

Additional information on (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt

Comprehensive Overview of (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt (CAS No. 117205-81-9)

The compound (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt (CAS No. 117205-81-9) is a highly specialized chiral building block widely utilized in pharmaceutical synthesis, agrochemical research, and advanced material science. Its unique stereochemistry and functional groups make it a valuable intermediate for asymmetric synthesis, particularly in the production of enantiomerically pure drugs and bioactive molecules. The potassium salt form enhances its solubility and reactivity, making it preferable for certain synthetic applications.

In recent years, the demand for chiral intermediates like (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt has surged due to the growing emphasis on green chemistry and sustainable manufacturing. Researchers and industries are increasingly focusing on reducing waste and improving atom economy, and this compound aligns perfectly with these goals. Its dioxolane ring structure provides stability while the carboxylic acid moiety offers versatility for further derivatization, making it a hotspot in modern synthetic chemistry.

One of the most frequently asked questions about CAS No. 117205-81-9 revolves around its applications in drug discovery. This compound is often employed in the synthesis of protease inhibitors, antiviral agents, and other therapeutic molecules. Its (4S) configuration ensures high enantioselectivity, which is critical for achieving desired pharmacological effects. Additionally, its compatibility with various coupling reactions makes it a favorite among medicinal chemists.

From an industrial perspective, the scalability of (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt is another key advantage. Manufacturers are increasingly adopting continuous flow chemistry and other innovative techniques to produce such intermediates efficiently. The compound’s stability under a wide range of conditions further enhances its appeal for large-scale applications. This aligns with the current trend of optimizing production processes to meet the demands of a rapidly evolving market.

Another area of interest is the role of dioxolane derivatives in material science. These compounds are being explored for their potential in creating biodegradable polymers and advanced coatings. The potassium salt form of this particular derivative offers improved handling and compatibility with aqueous systems, broadening its utility in environmentally friendly applications. This is particularly relevant given the global push towards sustainable materials and reduced environmental impact.

For researchers and procurement specialists, understanding the storage and handling of (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt is essential. While it is generally stable, proper storage conditions—such as protection from moisture and extreme temperatures—are recommended to maintain its integrity. This is a common query among users, highlighting the need for clear guidelines to ensure optimal performance in laboratory and industrial settings.

In summary, CAS No. 117205-81-9 represents a critical chiral intermediate with broad applications across multiple industries. Its unique structural features, combined with the growing demand for sustainable and efficient synthetic methods, position it as a compound of significant interest. Whether in drug development, agrochemical innovation, or advanced material design, (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Potassium Salt continues to play a pivotal role in cutting-edge research and industrial applications.

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