Cas no 51865-79-3 ((R)-Methotrexate)

(R)-Methotrexate structure

Product Name:(R)-Methotrexate

CAS No:51865-79-3

MF:C₂₀H₂₂N₈O₅

MW:454.439282894135

MDL:MFCD00006710

CID:370667

PubChem ID:329750409

Update Time:2025-04-19

(R)-Methotrexate Chemical and Physical Properties

Names and Identifiers

- D-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
- (R)-Methotrexate
- D-Amethopterin
- PHE-PHE
- (-) - AMETHOPTERIN - D - METHOTREXATE
- 6-MTX(D)
- D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID
- D(-)-AMETHOPTERIN
- D-(-)-AMETHOPTERIN HYDRATE
- D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid
- D-Glutamic acid, N-(4-(((2,4-diamino-6-pteridyl)methyl)methylamino)benzoyl)-
- d-methotrexate
- Einecs 257-482-2
- n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid
- (?)-Amethopterin
- Lopac-A-9898
- (2R)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid
- d(-)-Amethopterin hydrate,98
- Q27292170
- CHEMBL156
- DTXSID201317276
- UNII-W12798130R
- AKOS015895149
- NSC117356
- 51865-79-3
- TCMDC-125488
- (2R)-2-((4-(((2,4-DIAMINOPTERIDIN-6-YL)METHYL)METHYLAMINO)BENZOYL)AMINO)PENTANEDIOIC ACID
- BDBM50420238
- NSC 117356
- NCGC00016264-01
- NCGC00015079-01
- A 9898
- Methotrexate, (R)-
- 6UV
- W12798130R
- CAS-59-05-2-Batch2
- NCGC00016264-02
- 331717-43-2
- METHOTREXATE IMPURITY F [EP IMPURITY]
- R-methotrexate
- D-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
- (2R)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
- (-)Amethopterin
- CAS-59-05-2
- CCG-204190
- Methotrexate, d-
- (2R)-2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid
- (2R)-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid
- A828817
- R-METHOTREXATE [USP-RS]
- SCHEMBL171251
- NCGC00015079-02
- Lopac0_000095
- N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-D-glutamic acid
- Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, D-
- (2~{r})-2-[[4-[[2,4-Bis(Azanyl)pteridin-6-Yl]methyl-Methyl-Amino]phenyl]carbonylamino]pentanedioic Acid
- Lopac-A-6770
- D-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl][methyl]amino]benzoyl]-
- MDL： MFCD00006710
- Inchi： 1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m1/s1
- InChI Key： FBOZXECLQNJBKD-CYBMUJFWSA-N
- SMILES： OC([C@@H](CCC(=O)O)NC(C1C=CC(=CC=1)N(C)CC1C=NC2=C(C(N)=NC(N)=N2)N=1)=O)=O

Computed Properties

Exact Mass: 454.171
Monoisotopic Mass: 454.171
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 12
Heavy Atom Count: 33
Rotatable Bond Count: 9
Complexity: 704
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: _1.8
Topological Polar Surface Area: 211A^2

Experimental Properties

Density: 1.4080 (rough estimate)
Melting Point: 195 °C
Boiling Point: 561.26°C (rough estimate)
Flash Point: °C
Refractive Index: 1.6910 (estimate)
LogP: 1.82170

(R)-Methotrexate Security Information

Hazardous Material transportation number：UN 1544 6.1/PG 3
Hazard Category Code： 61-46-25-36/37/38-60-23/24/25
Safety Instruction： 53-45-28A-36/37/39-26-22
RTECS：MA1224000
Hazardous Material Identification：
Risk Phrases：61-46-25-36/37/38-60-23/24/25
Storage Condition：-20oC

(R)-Methotrexate Customs Data

HS CODE：29335995

(R)-Methotrexate Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	1413988-5MG	(R)-Methotrexate	51865-79-3		5mg	￥12013.15	2023-09-08
TRC	M260665-1mg	(R)-Methotrexate	51865-79-3		1mg	$ 224.00	2023-09-07
TRC	M260665-5mg	(R)-Methotrexate	51865-79-3		5mg	$ 850.00	2023-09-07
TRC	M260665-25mg	(R)-Methotrexate	51865-79-3		25mg	$ 3387.00	2023-09-07
A2B Chem LLC	AG26147-10mg	D(-)-AMETHOPTERIN	51865-79-3	98%	10mg	$1092.00	2024-04-19

(R)-Methotrexate Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:51865-79-3)D(-)-AMETHOPTERIN

Order Number:sfd21781

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:39

Price ($):discuss personally

Email:[email protected]

Product Official Link

(R)-Methotrexate Related Literature

1. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?

Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
2. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?

Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
3. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?

Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
4. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?

Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
5. Evolving better nanoparticles: Genetic algorithms for optimising cluster geometries

Dalton Trans., 2003, 4193-4207

Related Categories

Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pteridines and derivatives Pterins and derivatives Pteroic acids and derivatives

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