Cas no 510709-83-8 (1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride)

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride is a functionalized maleimide derivative featuring a primary amine group, making it a versatile intermediate for bioconjugation and crosslinking applications. The hydrochloride salt enhances stability and solubility in aqueous solutions, facilitating its use in biochemical and pharmaceutical research. The maleimide moiety selectively reacts with thiol groups under mild conditions, enabling efficient protein or peptide modification. The extended 5-aminopentyl linker provides flexibility, improving accessibility for conjugation with biomolecules. This compound is particularly useful for antibody-drug conjugate (ADC) development, surface functionalization, and polymer chemistry, offering precise control over molecular interactions. Its high purity and well-defined reactivity profile ensure reproducibility in synthetic workflows.
1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride structure
510709-83-8 structure
Product Name:1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride
CAS No:510709-83-8
MF:C9H15ClN2O2
MW:218.680601358414
MDL:MFCD11519192
CID:365956
PubChem ID:23354886
Update Time:2025-10-30

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 1H-Pyrrole-2,5-dione,1-(5-aminopentyl)-, hydrochloride (1:1)
    • 1H-Pyrrole-2,5-dione,1-(5-aminopentyl)-, monohydrochloride (9CI)
    • 1-(5-aminopentyl)pyrrole-2,5-dione,hydrochloride
    • N-(5-Aminopentyl)maleimide hydrochloride
    • N-(5-Aminopentyl)maleimide hydrochloride salt
    • 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione--hydrogen chloride (1/1)
    • 1-(5-aminopentyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride
    • 1H-Pyrrole-2,5-dione, 1-(5-aminopentyl)-, monohydrochloride
    • MFCD11519192
    • A7555
    • 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione HCl
    • EN300-6496373
    • DTXSID60633313
    • CS-0311812
    • M3226
    • N-(5-Aminopentyl)maleimide?hydrochloride?salt
    • 1-(5-Aminopentyl)-1H-pyrrole-2,5-dionehydrochloride
    • 510709-83-8
    • 1-(5-aminopentyl)pyrrole-2,5-dione;hydrochloride
    • SCHEMBL7515365
    • AMY21561
    • FT-0604047
    • 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione hydrochloride
    • G70083
    • 1-(5-AMINOPENTYL)PYRROLE-2,5-DIONE HYDROCHLORIDE
    • 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride
    • MDL: MFCD11519192
    • Inchi: 1S/C9H14N2O2.ClH/c10-6-2-1-3-7-11-8(12)4-5-9(11)13;/h4-5H,1-3,6-7,10H2;1H
    • InChI Key: ZKRSYXWTVSTKLW-UHFFFAOYSA-N
    • SMILES: Cl.O=C1C=CC(N1CCCCCN)=O

Computed Properties

  • Exact Mass: 218.082
  • Monoisotopic Mass: 218.082
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 5
  • Complexity: 218
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 63.4A^2

Experimental Properties

  • PSA: 63.40000
  • LogP: 1.48060

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride Pricemore >>

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Additional information on 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride

Comprehensive Overview of 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride (CAS No. 510709-83-8)

1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride (CAS 510709-83-8) is a specialized organic compound that has garnered significant attention in pharmaceutical and biochemical research. This hydrochloride salt derivative features a pyrrole-2,5-dione core, a structural motif known for its versatility in drug design and biological activity modulation. The compound's aminopentyl side chain enhances its solubility and potential for targeted interactions, making it a valuable intermediate in the synthesis of bioactive molecules.

In recent years, the demand for 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride has surged due to its applications in developing enzyme inhibitors and signal transduction modulators. Researchers are particularly interested in its role in designing small-molecule therapeutics for chronic diseases, aligning with the growing focus on precision medicine. The compound's CAS 510709-83-8 is frequently searched in academic databases, reflecting its relevance in cutting-edge studies.

The pyrrole-2,5-dione scaffold is a hotspot in medicinal chemistry due to its ability to mimic natural substrates and interact with biological targets. When combined with the aminopentyl moiety, this compound exhibits improved pharmacokinetic properties, such as enhanced membrane permeability. These attributes are critical for addressing challenges in drug delivery systems, a topic trending in biotech forums and AI-driven research platforms.

From a synthetic perspective, 1-(5-Aminopentyl)-1H-pyrrole-2,5-dione Hydrochloride is synthesized via controlled N-alkylation reactions, followed by salt formation. Its purity and stability are rigorously validated using advanced analytical techniques like HPLC and NMR spectroscopy, ensuring compliance with industry standards. Such protocols are often queried by chemists optimizing scalable production methods.

Beyond pharmaceuticals, this compound is explored in material science for designing functional polymers. Its dual reactivity (amine and dione groups) allows crosslinking applications, resonating with sustainability trends in polymer engineering. Searches for "biodegradable materials" and "smart polymers" frequently intersect with discussions about such derivatives.

In conclusion, CAS 510709-83-8 represents a multifaceted tool for innovation across disciplines. Its structural elegance and adaptability to green chemistry principles underscore its potential in next-generation research, answering pressing questions in health and technology.

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