Cas no 5080-50-2 (Acetyl L-Carnitine Hydrochloride)

Acetyl L-Carnitine Hydrochloride (ALCAR HCl) is a biologically active acetylated form of L-carnitine, featuring enhanced bioavailability and stability due to its hydrochloride salt formulation. This compound plays a critical role in cellular energy metabolism by facilitating the transport of fatty acids into mitochondria for β-oxidation. Its acetyl moiety further supports cognitive function by contributing to acetylcholine synthesis and promoting mitochondrial efficiency. ALCAR HCl is widely utilized in research and pharmaceutical applications for its neuroprotective and metabolic properties. The hydrochloride form ensures improved solubility and absorption, making it suitable for preclinical and clinical studies targeting neurological disorders, metabolic syndromes, and age-related cognitive decline.
Acetyl L-Carnitine Hydrochloride structure
5080-50-2 structure
Product Name:Acetyl L-Carnitine Hydrochloride
CAS No:5080-50-2
MF:C9H18ClNO4
MW:239.69652223587
MDL:MFCD00082230
CID:45516
PubChem ID:24891132
Update Time:2025-11-03

Acetyl L-Carnitine Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • (S)-3-Acetoxy-4-(trimethylammonio)butanoate hydrochloride
    • (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride
    • R(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
    • Levacecarnine hydrochloride
    • Acetyl-L-carnitine Hydrochloride
    • ALCAR
    • Acetyl L-Carnitine Hydrochloride
    • ACETYL-L-CARNITINE HCL(AS)
    • L-Acetylcarnitine (chloride)
    • O-Acetyl-L-carnitine hydrochloride
    • R-(-)-2-ACETOXY-3-CARBOXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM HYDROCHLORIDE
    • (R)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
    • Acetyl-L-carnitine hydrochloride ,Acetyl – L – Carnitine HCL
    • ALC
    • Acetyl L-carnitine HCl
    • R-(?)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
    • NSC-747431
    • [(2R)-2-acetoxy-3-carboxy-propyl]-trimethyl-ammonium
    • Nicetile
    • MLS001332368
    • 1-Propanaminium, 2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride, (2R)- (1:1)
    • Acetylcarnitine hydrochloride, l-
    • ST-200
    • Branigen
    • Normobren
    • Zibren
    • MFCD00082230
    • Acetyl-L-carnitine (hydrochloride)
    • Q27295965
    • Oristar ach
    • Acetylcarnitine L-form hydrochloride
    • Branigan
    • SMR000875234
    • O-acetylcarnitine
    • Acetylcarnitine hydrochloride
    • O-Acetyl-L-carnitine (hydrochloride)
    • O-Acetyl-L-carnitine HCl
    • HMS2233G09
    • AMMONIUM, (3-CARBOXY-2-HYDROXYPROPYL)TRIMETHYL-, CHLORIDE, ACETATE, (-)-
    • ACETYLCARNITINE HYDROCHLORIDE [MART.]
    • [(2R)-2-(acetyloxy)-3-carboxypropyl]trimethylazanium chloride
    • R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
    • AS-11664
    • ACETYLCARNITINE HYDROCHLORIDE [WHO-DD]
    • 1-Propanaminium,N,N-trimethyl-, chloride, (2R)-
    • (R)-2-Acetoxy-3-carboxy-N,N,N-trimethylpropan-1-aminium chloride
    • ACETYL CARNITINE HCL [INCI]
    • UNII-NDW10MX58T
    • 1-Propanaminium, 2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride, (R)-
    • NDW10MX58T
    • CHEMBL1321219
    • O-Acetyl-L-carnitine hydrochloride, >=99% (titration), powder
    • Acetylcarnitine chloride
    • CCG-266869
    • ACETYLCARNITINE HYDROCHLORIDE [MI]
    • (3-Carboxy-2-hydroxypropyl)trimethylammonium acetate (ester) chloride
    • 1-PROPANAMINIUM, 2-(ACETYLOXY)-3-CARBOXY-N,N,N-TRIMETHYL-, CHLORIDE (1:1), (2R)-
    • ACETYL-L-CARNITINE CHLORIDE
    • AKOS005138019
    • AC-004
    • NSC 747431
    • AKOS015963427
    • Acetyl-L-carnitine Hydrochloride, >/=99%
    • bmse000464
    • Acetylcarnitine L-form HCl
    • ACETYL CARNITINE HCL
    • acetyl-l-car-nitine hydrochloride
    • 5080-50-2
    • NSC747431
    • MLS001332367
    • A1394
    • MDL: MFCD00082230
    • Inchi: 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
    • InChI Key: JATPLOXBFFRHDN-DDWIOCJRSA-N
    • SMILES: [Cl-].O(C(C)=O)[C@H](CC(=O)O)C[N+](C)(C)C
    • BRN: 4340103

Computed Properties

  • Exact Mass: 239.09200
  • Monoisotopic Mass: 239.092
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 6
  • Complexity: 214
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Topological Polar Surface Area: 66.4

Experimental Properties

  • Color/Form: White powder
  • Melting Point: 194 oC
  • Boiling Point: °Cat760mmHg
  • Flash Point: °C
  • Refractive Index: -28 ° (C=1, H2O)
  • Solubility: H2O: 100?mg/mL
  • Water Partition Coefficient: dissolution
  • PSA: 63.60000
  • LogP: 0.90100
  • Merck: 84
  • Sensitiveness: Hygroscopic
  • Specific Rotation: -29 o (c=1, H2O)
  • Optical Activity: [α]25/D ?28°, c =?2 in H2O(lit.)
  • Solubility: It is easily soluble in water, slightly soluble in ethanol, and almost insoluble in ether.

Acetyl L-Carnitine Hydrochloride Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26; S36; S37/39
  • FLUKA BRAND F CODES:3-9
  • Hazardous Material Identification: Xi
  • Storage Condition:2-8°C
  • Safety Term:S26;S37/39
  • Risk Phrases:R36/37/38

Acetyl L-Carnitine Hydrochloride Pricemore >>

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Acetyl L-Carnitine Hydrochloride Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5080-50-2)O-Acetyl-L-carnitine hydrochloride
Order Number:LE2517;LE18744
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:42
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5080-50-2)Acetyl-L-carnitine hydrochloride
Order Number:sfd12342
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5080-50-2)
Order Number:SFD1386
Stock Status:
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Wednesday, 11 December 2024 17:02
Price ($):
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5080-50-2)Acetyl L-Carnitine Hydrochloride
Order Number:A828304
Stock Status:in Stock
Quantity:500g/1kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:27
Price ($):253.0/419.0

Acetyl L-Carnitine Hydrochloride Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Acetyl L-Carnitine Hydrochloride Related Literature

Additional information on Acetyl L-Carnitine Hydrochloride

Acetyl L-Carnitine Hydrochloride (CAS No. 5080-50-2): A Comprehensive Guide to Benefits and Applications

Acetyl L-Carnitine Hydrochloride (ALCAR), with CAS No. 5080-50-2, is a highly bioavailable form of L-carnitine that plays a crucial role in cellular energy metabolism. This compound has gained significant attention in recent years due to its potential cognitive, neurological, and metabolic benefits. As a derivative of the amino acid L-carnitine, Acetyl L-Carnitine HCl is widely used in dietary supplements, pharmaceuticals, and research applications.

The molecular structure of Acetyl L-Carnitine Hydrochloride includes an acetyl group attached to L-carnitine, which enhances its ability to cross the blood-brain barrier. This unique property makes it particularly valuable for supporting brain health and cognitive function. Researchers have identified ALCAR as a potential therapeutic agent for various conditions related to aging, neurodegeneration, and metabolic disorders.

One of the most frequently asked questions about Acetyl L-Carnitine HCl is "How does it differ from regular L-carnitine?" The key difference lies in the acetyl group, which allows for better absorption and utilization by the brain. This makes Acetyl L-Carnitine Hydrochloride particularly effective for neurological applications, while regular L-carnitine is more commonly used for physical performance and cardiovascular support.

Current research trends highlight the potential of Acetyl L-Carnitine (5080-50-2) in addressing age-related cognitive decline. Studies suggest that ALCAR may help maintain mitochondrial function in brain cells, support neurotransmitter production, and protect against oxidative stress. These properties have led to growing interest in ALCAR supplements for memory enhancement and neuroprotection.

The metabolic benefits of Acetyl L-Carnitine Hydrochloride extend beyond brain health. Many users search for information about "ALCAR for weight management" or "Acetyl L-Carnitine for energy." The compound facilitates fatty acid transport into mitochondria, where they are converted into energy. This mechanism has made Acetyl L-Carnitine HCl popular among athletes and individuals seeking metabolic support.

Quality considerations are paramount when selecting Acetyl L-Carnitine Hydrochloride products. The CAS No. 5080-50-2 specification ensures proper identification of the compound. Pharmaceutical-grade ALCAR should meet strict purity standards, typically exceeding 98% purity, with minimal impurities. These quality parameters are especially important for research and clinical applications.

Recent scientific investigations have explored the potential of Acetyl L-Carnitine in mood regulation. Search queries like "ALCAR for depression" or "Acetyl L-Carnitine for anxiety" reflect growing public interest in this application. Preliminary studies suggest that ALCAR Hydrochloride may influence neurotransmitter systems involved in mood regulation, though more research is needed in this area.

The safety profile of Acetyl L-Carnitine Hydrochloride (5080-50-2) is well-established at appropriate dosages. Common questions include "Is ALCAR safe for long-term use?" and "What are the side effects of Acetyl L-Carnitine?" Clinical studies have generally shown good tolerance, with mild gastrointestinal symptoms being the most frequently reported adverse effects at higher doses.

Manufacturing processes for Acetyl L-Carnitine HCl involve sophisticated chemical synthesis to ensure high purity and consistent quality. The production method must maintain the stereochemical integrity of the L-form, as this is crucial for biological activity. Proper storage conditions are also essential to maintain the stability of Acetyl L-Carnitine Hydrochloride powder or capsules.

Emerging research directions for Acetyl L-Carnitine (CAS 5080-50-2) include its potential role in supporting healthy aging and longevity. Scientists are investigating how ALCAR supplementation might influence cellular aging markers and mitochondrial function over time. These studies contribute to the growing body of evidence supporting the diverse applications of this remarkable compound.

When considering Acetyl L-Carnitine Hydrochloride supplementation, dosage recommendations vary depending on the intended use. Common search queries include "How much ALCAR should I take?" and "What's the best time to take Acetyl L-Carnitine?" Clinical studies have used doses ranging from 500 mg to 3,000 mg daily, typically divided into two or three administrations.

The global market for Acetyl L-Carnitine HCl continues to expand, driven by increasing awareness of its potential health benefits. Quality suppliers of CAS No. 5080-50-2 material must provide comprehensive analytical documentation, including certificates of analysis, HPLC purity reports, and stability data. These quality assurance measures are critical for research institutions and manufacturers.

Future research on Acetyl L-Carnitine Hydrochloride may explore its synergistic effects with other nootropics and neuroprotective compounds. The scientific community continues to investigate the full spectrum of biological activities associated with ALCAR, potentially uncovering new therapeutic applications for this versatile molecule.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:5080-50-2)O-Acetyl-L-carnitine hydrochloride
LE2517;LE18744
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:5080-50-2)Acetyl-L-carnitine hydrochloride
sfd12342
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email