Cas no 369651-88-7 (DECANOYL-L-CARNITINE CHLORIDE)
DECANOYL-L-CARNITINE CHLORIDE Chemical and Physical Properties
Names and Identifiers
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- Decanoyl-L-carnitine Chloride
- CID 131667485
- CAPRYL-L-CARNITINE CHLORIDE
- CAPRYL-CARNITINE CHLORIDE
- (3R)-3-Decanoyloxy-4-(trimethylazaniumyl)butanoate;hydrochloride
- 369651-88-7
- DECANOYL-L-CARNITINE CHLORIDE
-
- Inchi: 1S/C17H33NO4.ClH/c1-5-6-7-8-9-10-11-12-17(21)22-15(13-16(19)20)14-18(2,3)4;/h15H,5-14H2,1-4H3;1H/t15-;/m1./s1
- InChI Key: KETNUEKCBCWXCU-XFULWGLBSA-N
- SMILES: Cl.O(C(CCCCCCCCC)=O)[C@H](CC(=O)[O-])C[N+](C)(C)C
Computed Properties
- Exact Mass: 351.2176363g/mol
- Monoisotopic Mass: 351.2176363g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 23
- Rotatable Bond Count: 13
- Complexity: 318
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.4
Experimental Properties
- Melting Point: 166-170°C
- Solubility: DMSO (Slightly), Methanol (Slightly)
DECANOYL-L-CARNITINE CHLORIDE Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D212580-250mg |
Decanoyl-L-carnitine Chloride |
369651-88-7 | 250mg |
$ 199.00 | 2023-09-08 | ||
| TRC | D212580-2.5g |
Decanoyl-L-carnitine Chloride |
369651-88-7 | 2.5g |
$ 1581.00 | 2023-09-08 | ||
| Larodan | 17-1000-39-100ug |
Decanoyl-L-Carnitine HCl salt |
369651-88-7 | >98% | 100ug |
€47.00 | 2023-09-19 | |
| Larodan | 17-1000-7-25mg |
Decanoyl-L-Carnitine HCl salt |
369651-88-7 | >98% | 25mg |
€173.00 | 2025-03-07 | |
| Larodan | 17-1000-8-50mg |
Decanoyl-L-Carnitine HCl salt |
369651-88-7 | >98% | 50mg |
€276.00 | 2025-03-07 | |
| Larodan | 17-1000-9-100mg |
Decanoyl-L-Carnitine HCl salt |
369651-88-7 | >98% | 100mg |
€483.00 | 2025-03-07 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci71028-5mg |
Decanoyl-L-carnitine (chloride) |
369651-88-7 | 98% | 5mg |
¥680.00 | 2022-04-26 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci71028-10mg |
Decanoyl-L-carnitine (chloride) |
369651-88-7 | 98% | 10mg |
¥1086.00 | 2022-04-26 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci71028-25mg |
Decanoyl-L-carnitine (chloride) |
369651-88-7 | 98% | 25mg |
¥2299.00 | 2022-04-26 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci71028-50mg |
Decanoyl-L-carnitine (chloride) |
369651-88-7 | 98% | 50mg |
¥3987.00 | 2022-04-26 |
DECANOYL-L-CARNITINE CHLORIDE Suppliers
DECANOYL-L-CARNITINE CHLORIDE Related Literature
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Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
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Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
Additional information on DECANOYL-L-CARNITINE CHLORIDE
Professional Introduction to DECANOYL-L-CARNITINE CHLORIDE (CAS No. 369651-88-7)
DECANOYL-L-CARNITINE CHLORIDE, with the chemical identifier CAS No. 369651-88-7, is a compound of significant interest in the field of biochemical research and pharmaceutical development. This compound belongs to the class of acylcarnitines, which are derivatives of carnitine—a naturally occurring amino acid involved in energy metabolism. The acylation of carnitine with a decanoyl group introduces unique biochemical properties, making it a valuable candidate for various therapeutic applications.
The structure of DECANOYL-L-CARNITINE CHLORIDE consists of a carnitine backbone linked to a decanoic acid moiety, with the chloride salt form enhancing its solubility and reactivity. This structural configuration imparts distinct pharmacokinetic and pharmacodynamic characteristics, which have been the focus of numerous studies in recent years. The compound's ability to modulate mitochondrial function and fatty acid transport has garnered attention for its potential in addressing metabolic disorders and enhancing cellular energy production.
Recent research has highlighted the role of acylcarnitines in modulating lipid metabolism and improving insulin sensitivity. Studies have demonstrated that DECANOYL-L-CARNITINE CHLORIDE can enhance mitochondrial biogenesis and improve the efficiency of fatty acid oxidation, particularly in tissues such as muscle and liver. These effects are particularly relevant in the context of metabolic syndrome, obesity, and type 2 diabetes, where impaired mitochondrial function contributes significantly to disease progression.
In clinical settings, DECANOYL-L-CARNITINE CHLORIDE has been investigated for its potential therapeutic benefits in improving exercise performance and recovery. Preclinical studies suggest that this compound can enhance endurance capacity by facilitating the transport of long-chain fatty acids into mitochondria, thereby increasing energy production during periods of high demand. Additionally, its ability to reduce oxidative stress and inflammation may contribute to faster recovery times and reduced muscle damage following intense physical activity.
The pharmacological profile of DECANOYL-L-CARNITINE CHLORIDE also makes it a promising candidate for neuroprotective applications. Emerging evidence indicates that acylcarnitines can cross the blood-brain barrier and exert neuroprotective effects by mitigating mitochondrial dysfunction and oxidative damage. This has led to investigations into its potential use in neurodegenerative diseases such as Alzheimer's and Parkinson's, where mitochondrial impairment is a key pathological feature.
From a synthetic chemistry perspective, the preparation of DECANOYL-L-CARNITINE CHLORIDE involves well-established protocols for acylation and salt formation. The synthesis typically begins with the esterification of L-carnitine with decanoic acid under controlled conditions, followed by conversion to the chloride salt to enhance solubility. Advances in synthetic methodologies have improved the yield and purity of this compound, making it more accessible for research and development purposes.
The growing body of evidence supporting the therapeutic potential of DECANOYL-L-CARNITINE CHLORIDE has prompted further exploration into its mechanism of action at a molecular level. Research using spectroscopic techniques such as NMR and mass spectrometry has provided insights into how this compound interacts with cellular components, particularly mitochondrial enzymes involved in fatty acid transport and oxidation. These studies are crucial for understanding its efficacy and identifying potential off-target effects.
In conclusion, DECANOYL-L-CARNITINE CHLORIDE (CAS No. 369651-88-7) represents a significant advancement in the field of metabolic research and therapeutic development. Its unique biochemical properties, combined with emerging evidence from clinical and preclinical studies, position it as a promising candidate for addressing a range of metabolic disorders and enhancing cellular energy production. As research continues to uncover new applications for this compound, its importance in both academic research and pharmaceutical innovation is likely to grow.
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