• 1. Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction?
  Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
• 2. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 3. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 5. Estimation of hydrogen sulfide from crude petroleum: a unique invention using a simple chemosensor?
  Shampa Kundu,Prithidipa Sahoo New J. Chem., 2019,43, 12369-12374

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Long-chain fatty alcohols
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty alcohols Long-chain fatty alcohols

Recent Advances in the Study of Tetradecanoic acid, 14-hydroxy-, methyl ester (CAS: 50515-98-5) in Chemical Biology and Pharmaceutical Research

In recent years, Tetradecanoic acid, 14-hydroxy-, methyl ester (CAS: 50515-98-5) has garnered significant attention in the field of chemical biology and pharmaceutical research. This compound, a derivative of myristic acid, has shown promising potential in various applications, including drug development, antimicrobial agents, and lipid metabolism studies. The unique structural features of this molecule, characterized by a hydroxyl group at the 14th carbon and a methyl ester moiety, contribute to its diverse biological activities and make it a valuable subject for scientific investigation.

Recent studies have focused on elucidating the synthesis, characterization, and biological evaluation of Tetradecanoic acid, 14-hydroxy-, methyl ester. Advanced spectroscopic techniques such as NMR, IR, and mass spectrometry have been employed to confirm its structural integrity and purity. Additionally, computational modeling has provided insights into its molecular interactions and potential binding sites, which are crucial for understanding its mechanism of action in biological systems.

One of the most notable findings in recent research is the compound's antimicrobial properties. In vitro studies have demonstrated its efficacy against a range of Gram-positive and Gram-negative bacteria, as well as fungal pathogens. The compound's ability to disrupt microbial cell membranes, combined with its relatively low cytotoxicity to mammalian cells, positions it as a promising candidate for the development of novel antimicrobial agents. Further investigations are underway to optimize its activity and explore its potential in combination therapies.

Beyond its antimicrobial applications, Tetradecanoic acid, 14-hydroxy-, methyl ester has also been studied for its role in lipid metabolism and signaling pathways. Research indicates that this compound may influence key enzymes involved in fatty acid biosynthesis and degradation, making it a potential modulator of metabolic disorders such as obesity and diabetes. Animal models have shown that administration of the compound can lead to measurable changes in lipid profiles, suggesting its therapeutic potential in metabolic diseases.

In the pharmaceutical industry, the compound's utility as an intermediate in the synthesis of more complex molecules has been explored. Its hydroxyl and ester functional groups provide reactive sites for further chemical modifications, enabling the creation of derivatives with enhanced biological activities or improved pharmacokinetic properties. Several patents have been filed in recent years, highlighting its commercial potential in drug discovery and development.

Despite these advancements, challenges remain in the large-scale production and formulation of Tetradecanoic acid, 14-hydroxy-, methyl ester. Current synthetic routes often involve multiple steps with moderate yields, prompting ongoing research into more efficient and sustainable methodologies. Additionally, further preclinical and clinical studies are needed to fully assess its safety and efficacy in therapeutic applications.

In conclusion, Tetradecanoic acid, 14-hydroxy-, methyl ester (CAS: 50515-98-5) represents a compound of growing importance in chemical biology and pharmaceutical research. Its diverse biological activities, coupled with its potential as a drug candidate and synthetic intermediate, make it a subject of intense scientific interest. As research continues to uncover new applications and optimize its properties, this compound is likely to play an increasingly significant role in addressing current challenges in medicine and biotechnology.

• 110-38-3(Ethyl decanoate)
• 110-40-7(Diethyl decanedioate)
• 106-65-0(Dimethyl succinate)
• 106-32-1(Ethyl n-Caprylate)
• 112-39-0(Methyl palmitate)
• 106-02-5(ω-Pentadecalactone)
• 110-42-9(Methyl decanoate)
• 106-30-9(Ethyl Heptanoate(Heptanoic Acid Ethyl Ester))
• 106-33-2(Ethyl Laurate(Ethyl Dodecanoate))
• 109-43-3(dibutyl sebacate)