• 1. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
  Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
• 2. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 3. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 4. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 5. Enabling stable MnO2 matrix for aqueous zinc-ion battery cathodes?
  Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082

3-(Pyrrolidin-2-yl)Quinoline: A Comprehensive Overview

3-(Pyrrolidin-2-yl)Quinoline, also known by its CAS number 499207-38-4, is a compound of significant interest in the fields of organic chemistry and pharmacology. This molecule, characterized by its unique structure combining a quinoline ring with a pyrrolidine substituent, has garnered attention due to its potential applications in drug discovery and materials science.

The quinoline moiety, a heterocyclic aromatic compound, is well-known for its versatility in chemical synthesis and biological activity. The addition of a pyrrolidine group at the 3-position of the quinoline ring introduces new functional groups and enhances the molecule's chemical reactivity and bioavailability. Recent studies have highlighted the importance of such structural modifications in optimizing pharmacokinetic properties and improving therapeutic efficacy.

One of the most promising areas of research involving 3-(Pyrrolidin-2-yl)Quinoline is its potential as a scaffold for drug development. Researchers have explored its ability to act as a receptor antagonist or enzyme inhibitor, making it a valuable tool in the study of various disease states, including cancer, inflammation, and neurodegenerative disorders.

In terms of synthesis, 3-(Pyrrolidin-2-yl)Quinoline can be prepared through several methods, including coupling reactions and cyclization processes. Recent advancements in catalytic asymmetric synthesis have enabled the production of enantiomerically pure derivatives, which are crucial for studying stereochemical effects on biological activity.

The compound's properties also make it an interesting candidate for materials science applications. Its aromaticity and conjugated system contribute to electronic properties that could be harnessed in organic electronics or photovoltaic devices. Ongoing research is exploring how modifications to the pyrrolidine group can further enhance these properties.

In conclusion, 3-(Pyrrolidin-2-yl)Quinoline represents a versatile platform for both chemical and biological exploration. Its unique structure, combined with recent advances in synthetic methodology and biological testing, positions it as a key compound in future research endeavors across multiple disciplines.

• 694425-25-7(1H-Indole,3-(1-ethyl-2-pyrrolidinyl)-(9CI))
• 19137-96-3(3-(1-benzylpyrrolidin-2-yl)-1h-indole)
• 19137-69-0(5-methyl-3-(1-methylpyrrolidin-2-yl)-1H-indole)
• 19137-65-6(2-(1H-indol-3-yl)-5-methylpyrrolidinium chloride)
• 717816-94-9(3-(5-Ethyl-2-pyrrolidinyl)-1H-indole)
• 3766-03-8(3-Pyrrolidin-2-yl-1H-indole)
• 527673-84-3(8-AZEPAN-2-YL-QUINOLINE)
• 19137-66-7(3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole)
• 19137-74-7(2-ethyl-5-(1H-indol-3-yl)pyrrolidinium chloride)
• 860299-05-4(6-(pyrrolidin-2-yl)quinoline)