Cas no 49673-74-7 (Cyclohexanol, 3-phenyl-)

3-Phenylcyclohexanol is a cyclic alcohol featuring a phenyl substituent at the 3-position of the cyclohexane ring. This compound is of interest in organic synthesis and pharmaceutical research due to its structural versatility, serving as a key intermediate in the preparation of more complex molecules. The presence of both hydroxyl and phenyl groups allows for selective functionalization, enabling applications in fine chemical and material science industries. Its stable cyclohexane backbone contributes to predictable reactivity, while the phenyl group enhances solubility in organic solvents. The compound is typically characterized by standard analytical techniques, including NMR and GC-MS, ensuring high purity for research and industrial use.
Cyclohexanol, 3-phenyl- structure
Cyclohexanol, 3-phenyl- structure
Product Name:Cyclohexanol, 3-phenyl-
CAS No:49673-74-7
MF:C12H16O
MW:176.254843711853
MDL:MFCD06654263
CID:333737
PubChem ID:300424
Update Time:2025-10-19

Cyclohexanol, 3-phenyl- Chemical and Physical Properties

Names and Identifiers

    • Cyclohexanol, 3-phenyl-
    • 3-phenylcyclohexan-1-ol
    • 3-phenylcyclohexanol
    • (1S,3R)-3-phenylcyclohexanol
    • 3-phenyl-1-cyclohexanol
    • cis-3-Phenyl-cyclohexanol
    • Cyclohexanol,3-phenyl
    • trans-3-Phenyl-cyclohexanol
    • 3-Phenyl-cyclohexanol
    • AKOS006292591
    • SCHEMBL787976
    • D85581
    • WS-03151
    • CS-0342704
    • NSC-174840
    • NSC174840
    • DTXSID10306267
    • FT-0770364
    • SB37353
    • 49673-74-7
    • 22147-17-7
    • DA-05488
    • MDL: MFCD06654263
    • Inchi: 1S/C12H16O/c13-12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-3,5-6,11-13H,4,7-9H2
    • InChI Key: YXBPBFIAVFWQMT-UHFFFAOYSA-N
    • SMILES: OC1CCCC(C2C=CC=CC=2)C1

Computed Properties

  • Exact Mass: 176.12000
  • Monoisotopic Mass: 176.12
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 149
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.7
  • Topological Polar Surface Area: 20.2?2

Experimental Properties

  • Density: 1.051
  • Boiling Point: 295.8°Cat760mmHg
  • Flash Point: 113.3°C
  • Refractive Index: 1.553
  • PSA: 20.23000
  • LogP: 2.70510

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Cyclohexanol, 3-phenyl- Production Method

Cyclohexanol, 3-phenyl- Suppliers

Amadis Chemical Company Limited
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(CAS:49673-74-7)Cyclohexanol, 3-phenyl-
Order Number:A1037989
Stock Status:in Stock
Quantity:5g/500mg/250mg/100mg/50mg/1g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 17:02
Price ($):2189.0/492.0/301.0/205.0/158.0/874.0

Additional information on Cyclohexanol, 3-phenyl-

Introduction to Cyclohexanol, 3-phenyl- (CAS No. 49673-74-7)

Cyclohexanol, 3-phenyl-, identified by its Chemical Abstracts Service (CAS) number 49673-74-7, is a significant organic compound with a broad spectrum of applications in pharmaceuticals, agrochemicals, and specialty chemicals. This compound belongs to the class of phenyl-substituted cyclohexanols, which have garnered considerable attention due to their unique structural and functional properties. The presence of both cyclohexane and phenyl groups imparts distinct reactivity and utility, making it a valuable intermediate in synthetic chemistry.

The molecular structure of Cyclohexanol, 3-phenyl- consists of a cyclohexane ring substituted with a phenyl group at the 3-position, along with a hydroxyl (-OH) functional group. This arrangement contributes to its versatility in chemical transformations, enabling its use as a precursor in the synthesis of more complex molecules. The compound exhibits moderate solubility in organic solvents such as ethanol, acetone, and dichloromethane, which facilitates its incorporation into various chemical processes.

In recent years, Cyclohexanol, 3-phenyl- has been the subject of extensive research due to its potential applications in drug development. Studies have highlighted its role as a key intermediate in the synthesis of pharmacologically active compounds. For instance, derivatives of this molecule have been explored for their antimicrobial and anti-inflammatory properties. The phenyl group enhances binding affinity to biological targets, making it an attractive scaffold for medicinal chemists.

One of the most compelling aspects of Cyclohexanol, 3-phenyl- is its utility in the synthesis of fine chemicals and specialty materials. Researchers have leveraged its reactivity to develop novel polymers and coatings with enhanced durability and functionality. The compound's ability to undergo various chemical reactions, such as oxidation and alkylation, makes it a versatile building block for industrial applications.

The pharmaceutical industry has shown particular interest in Cyclohexanol, 3-phenyl- due to its potential as a precursor for bioactive molecules. Recent studies have demonstrated its incorporation into drug candidates targeting neurological disorders. The cyclohexanol moiety provides a favorable pharmacokinetic profile, while the phenyl group enhances interactions with biological receptors. This combination has led to promising results in preclinical trials.

Furthermore, Cyclohexanol, 3-phenyl- has found applications in agrochemical formulations. Its structural features make it an effective component in pesticide and herbicide formulations, contributing to improved crop protection strategies. The compound's stability under various environmental conditions enhances its efficacy in agricultural settings.

The synthesis of Cyclohexanol, 3-phenyl- typically involves catalytic hydrogenation or Grignard reactions starting from phenol derivatives. Advanced synthetic methodologies have been developed to improve yield and purity, ensuring that industrial-scale production meets stringent quality standards. These advancements underscore the compound's importance as a commercial chemical.

From an environmental perspective, efforts have been made to optimize the production process of Cyclohexanol, 3-phenyl- to minimize waste and reduce energy consumption. Green chemistry principles have been applied to develop more sustainable synthetic routes, aligning with global efforts toward eco-friendly chemical manufacturing.

The future prospects for Cyclohexanol, 3-phenyl- are promising, with ongoing research exploring new applications in material science and biotechnology. Its unique structural properties make it a candidate for innovative solutions in areas such as nanotechnology and biodegradable materials. As scientific understanding advances, the potential uses for this compound are expected to expand further.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:49673-74-7)Cyclohexanol, 3-phenyl-
A1037989
Purity:99%/99%/99%/99%/99%/99%
Quantity:5g/500mg/250mg/100mg/50mg/1g
Price ($):2189.0/492.0/301.0/205.0/158.0/874.0
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