Cas no 488713-31-1 (5-amino-3-chloropicolinonitrile)
5-Amino-3-chloropicolinonitrile is a versatile heterocyclic compound featuring both amino and chloro functional groups on a picolinonitrile scaffold. This structure imparts reactivity suitable for further derivatization, making it valuable in pharmaceutical and agrochemical synthesis. The presence of the electron-withdrawing nitrile group enhances its utility in nucleophilic substitution reactions, while the amino group allows for condensation or coupling reactions. Its chlorinated pyridine core contributes to stability and selectivity in cross-coupling processes. The compound is particularly useful as an intermediate in the development of active ingredients, offering a balance of reactivity and modularity for tailored molecular design. Proper handling under controlled conditions is recommended due to its reactive functional groups.
488713-31-1 structure
Product Name:5-amino-3-chloropicolinonitrile
CAS No:488713-31-1
MF:C6H4ClN3
MW:153.569059371948
MDL:MFCD11977423
CID:324763
PubChem ID:21875099
Update Time:2025-05-27
5-amino-3-chloropicolinonitrile Chemical and Physical Properties
Names and Identifiers
-
- 5-amino-3-chloropyridine-2-carbonitrile
- 5-amino-3-chloropicolinonitrile
- 2 -Pyridinecarbonitrile, 5-amino-3-chloro-
- 5-Amino-3-chloro-2-cyanopyridine
- 2-PYRIDINECARBONITRILE, 5-AMINO-3-CHLORO-
- AKOS025404196
- CHEMBL4559536
- SCHEMBL1303846
- DS-10092
- 2-PYRIDINECARBONITRILE,5-AMINO-3-CHLORO-
- GDIBYDQLRIRVCQ-UHFFFAOYSA-N
- AB65150
- EN300-233607
- DTXSID70619244
- A827618
- 488713-31-1
- CS-0043966
- 5-amino-3-chloro-2-pyridinecarbonitrile
- MFCD11977423
- 5-azanyl-3-chloranyl-pyridine-2-carbonitrile
-
- MDL： MFCD11977423
- Inchi： 1S/C6H4ClN3/c7-5-1-4(9)3-10-6(5)2-8/h1,3H,9H2
- InChI Key： GDIBYDQLRIRVCQ-UHFFFAOYSA-N
- SMILES： ClC1=C(C#N)N=CC(=C1)N
Computed Properties
- Exact Mass: 153.009
- Monoisotopic Mass: 153.009
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 162
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 62.7A^2
- XLogP3: 0.9
Experimental Properties
- Color/Form: No data avaiable
- Density: 1.42±0.1 g/cm3 (20 oC 760 Torr),
- Melting Point: No data available
- Boiling Point: 400.477 °C at 760 mmHg
- Flash Point: 196.001 °C
- Solubility: Slightly soluble (2.8 g/l) (25 o C),
- Vapor Pressure: 0.0±0.0 mmHg at 25°C
5-amino-3-chloropicolinonitrile Security Information
- Signal Word：Warning
- Hazard Statement： H302 (100%) H312 (100%) H315 (100%)
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction： H302 (100%) H312 (100%) H315 (100%)
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
5-amino-3-chloropicolinonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-100mg |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 100mg |
462CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-250mg |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 250mg |
910CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-1g |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 1g |
2700.0CNY | 2021-08-03 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-5g |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 5g |
7560.0CNY | 2021-08-03 | |
| Chemenu | CM253162-1g |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 1g |
$422 | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-50mg |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 50mg |
240.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IY189-200mg |
5-amino-3-chloropicolinonitrile |
488713-31-1 | 97% | 200mg |
675.0CNY | 2021-08-04 | |
| Alichem | A029016153-100mg |
5-Amino-3-chloropicolinonitrile |
488713-31-1 | 95% | 100mg |
$152.71 | 2023-09-01 | |
| Alichem | A029016153-250mg |
5-Amino-3-chloropicolinonitrile |
488713-31-1 | 95% | 250mg |
$243.27 | 2023-09-01 | |
| Alichem | A029016153-1g |
5-Amino-3-chloropicolinonitrile |
488713-31-1 | 95% | 1g |
$609.51 | 2023-09-01 |
5-amino-3-chloropicolinonitrile Related Literature
-
Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
-
Felix Witte,Philipp Rietsch,Nithiya Nirmalananthan-Budau,Florian Weigert,Jan P. G?tze,Ute Resch-Genger,Siegfried Eigler,Beate Paulus Phys. Chem. Chem. Phys., 2021,23, 17521-17529
-
Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644
-
Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864
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