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• 2. An aquatic host–guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin?
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• 3. An integrated cathode and solid electrolyte via in situ polymerization with significantly reduced interface resistance?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Pyrazines
• Solvents and Organic Chemicals Organic Compounds Heterocyclic Compounds

Comprehensive Overview of 2,3-Dichloropyrazine (CAS No. 4858-85-9): Properties, Applications, and Industry Insights

2,3-Dichloropyrazine (CAS No. 4858-85-9) is a heterocyclic organic compound featuring a pyrazine ring substituted with two chlorine atoms at the 2 and 3 positions. This chlorinated pyrazine derivative is widely recognized for its versatility in pharmaceutical, agrochemical, and material science applications. Its molecular formula, C₄H₂Cl₂N₂, and unique structural properties make it a valuable intermediate in synthetic chemistry. The compound’s high reactivity and selective functionalization capabilities have spurred interest in research and industrial sectors, particularly in the development of novel bioactive molecules.

In recent years, the demand for 2,3-Dichloropyrazine has grown due to its role in synthesizing advanced pharmaceutical ingredients (APIs) and crop protection agents. Researchers are increasingly exploring its potential in drug discovery, especially for targeting kinase inhibitors and antiviral compounds. A trending topic in the scientific community is the compound’s utility in green chemistry initiatives, where its derivatives are designed to minimize environmental impact. This aligns with global searches for sustainable chemical synthesis methods, a frequently queried topic in AI-driven research platforms.

The physical and chemical properties of 2,3-Dichloropyrazine contribute to its broad applicability. It typically appears as a white to off-white crystalline solid with a melting point ranging between 45–50°C. Its solubility in organic solvents like ethanol, acetone, and dichloromethane makes it ideal for multistep organic reactions. Analytical techniques such as HPLC, GC-MS, and NMR spectroscopy are commonly employed to verify its purity and structure, addressing another frequent user query: “How to characterize 2,3-Dichloropyrazine?”

From an industrial perspective, 2,3-Dichloropyrazine is a key building block for specialty chemicals. Its derivatives are integral to the production of electronic materials, including OLEDs and organic semiconductors, reflecting the surge in searches for “pyrazine-based functional materials.” Additionally, its role in flavor and fragrance formulations—owing to its nitrogen-rich aromatic profile—has garnered attention in the food and cosmetics industries.

Quality control and regulatory compliance are critical for CAS No. 4858-85-9. Manufacturers adhere to stringent guidelines, such as ISO 9001 and REACH, ensuring safety and consistency. Users often search for “2,3-Dichloropyrazine suppliers” and “technical specifications,” emphasizing the need for transparent data sheets and certifications. Storage recommendations typically include cool, dry conditions in airtight containers to prevent degradation.

Emerging trends highlight the compound’s potential in catalysis and nanotechnology. For instance, its integration into metal-organic frameworks (MOFs) for gas storage applications is a hot research topic. Furthermore, the rise of computational chemistry tools has enabled predictive modeling of 2,3-Dichloropyrazine reactivity, addressing queries like “How to optimize pyrazine reactions?” with AI-assisted insights.

In conclusion, 2,3-Dichloropyrazine (CAS No. 4858-85-9) remains a cornerstone in modern chemistry, bridging gaps between academia and industry. Its multifaceted applications—from life sciences to advanced materials—underscore its enduring relevance. As sustainability and innovation drive chemical research, this compound will likely continue to inspire breakthroughs, making it a focal point for professionals and enthusiasts alike.

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