Cas no 476622-92-1 (7-(benzyloxy)-4-bromo-1h-indole)
7-(Benzyloxy)-4-bromo-1H-indole is a brominated indole derivative featuring a benzyloxy substituent at the 7-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and bioactive molecules. The presence of the bromine atom at the 4-position enhances its reactivity, enabling efficient cross-coupling reactions such as Suzuki or Buchwald-Hartwig couplings for further functionalization. The benzyloxy group provides a protective moiety for the hydroxyl functionality, allowing selective deprotection under mild conditions. Its stable crystalline form ensures ease of handling and storage. This compound is valuable in medicinal chemistry for constructing indole-based scaffolds, which are prevalent in drug discovery targeting serotonin receptors, kinase inhibitors, and other therapeutic agents.
476622-92-1 structure
Product Name:7-(benzyloxy)-4-bromo-1h-indole
CAS No:476622-92-1
MF:C15H12BrNO
MW:302.16588306427
MDL:MFCD08272258
CID:890152
PubChem ID:11460828
Update Time:2025-07-02
7-(benzyloxy)-4-bromo-1h-indole Chemical and Physical Properties
Names and Identifiers
-
- 4-BROMO-7-BENZYLOXY-1H-INDOLE
- 1H-Indole,4-broMo-7-(phenylMethoxy)
- 7-(benzyloxy)-4-bromo-1H-indole
- 7-benzyloxy-4-bromoindole
- HWDMSYHNPIYTJF-UHFFFAOYSA-N
- DTXSID501295354
- F77950
- EN300-12577993
- 476622-92-1
- 4-Bromo-7-(phenylmethoxy)-1H-indole
- 4-bromo-7-phenylmethoxy-1H-indole
- PS-15496
- SCHEMBL3621324
- 7-(benzyloxy)-4-bromo-1h-indole
-
- MDL： MFCD08272258
- Inchi： 1S/C15H12BrNO/c16-13-6-7-14(15-12(13)8-9-17-15)18-10-11-4-2-1-3-5-11/h1-9,17H,10H2
- InChI Key： HWDMSYHNPIYTJF-UHFFFAOYSA-N
- SMILES： BrC1=CC=C(C2=C1C=CN2)OCC1C=CC=CC=1
Computed Properties
- Exact Mass: 301.01000
- Monoisotopic Mass: 301.01023g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 18
- Rotatable Bond Count: 3
- Complexity: 267
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 4.2
- Topological Polar Surface Area: 25?2
Experimental Properties
- PSA: 25.02000
- LogP: 4.50940
7-(benzyloxy)-4-bromo-1h-indole Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
7-(benzyloxy)-4-bromo-1h-indole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B796893-10mg |
7-(Benzyloxy)-4-bromo-1H-indole |
476622-92-1 | 10mg |
$ 50.00 | 2022-06-06 | ||
| TRC | B796893-50mg |
7-(Benzyloxy)-4-bromo-1H-indole |
476622-92-1 | 50mg |
$ 210.00 | 2022-06-06 | ||
| TRC | B796893-100mg |
7-(Benzyloxy)-4-bromo-1H-indole |
476622-92-1 | 100mg |
$ 295.00 | 2022-06-06 | ||
| Aaron | AR00DEU5-1g |
4-BROMO-7-BENZYLOXY-1H-INDOLE |
476622-92-1 | 97% | 1g |
$575.00 | 2025-02-13 | |
| Aaron | AR00DEU5-500mg |
4-BROMO-7-BENZYLOXY-1H-INDOLE |
476622-92-1 | 97% | 500mg |
$303.00 | 2025-02-13 | |
| eNovation Chemicals LLC | Y1298773-250mg |
7-(benzyloxy)-4-bromo-1h-indole |
476622-92-1 | 97% | 250mg |
$215 | 2025-02-20 | |
| eNovation Chemicals LLC | Y1298773-100mg |
7-(benzyloxy)-4-bromo-1h-indole |
476622-92-1 | 97% | 100mg |
$120 | 2025-02-20 | |
| eNovation Chemicals LLC | Y1298773-1g |
7-(benzyloxy)-4-bromo-1h-indole |
476622-92-1 | 97% | 1g |
$570 | 2025-02-20 | |
| eNovation Chemicals LLC | Y1298773-500mg |
7-(benzyloxy)-4-bromo-1h-indole |
476622-92-1 | 97% | 500mg |
$340 | 2025-02-20 | |
| eNovation Chemicals LLC | Y1298773-5g |
7-(benzyloxy)-4-bromo-1h-indole |
476622-92-1 | 97% | 5g |
$2860 | 2025-02-20 |
7-(benzyloxy)-4-bromo-1h-indole Related Literature
-
Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
-
Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
-
Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
-
Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
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