Cas no 476310-60-8 (VO-Ohpic trihydrate)
VO-Ohpic trihydrate is a potent and selective inhibitor of the hypoxia-inducible factor (HIF) prolyl hydroxylase domain-containing enzyme 2 (PHD2), which plays a critical role in cellular oxygen sensing. This compound stabilizes HIF-1α by inhibiting its hydroxylation, thereby promoting HIF-mediated transcriptional activity. VO-Ohpic trihydrate is widely utilized in biochemical and pharmacological research to study hypoxia-related pathways, including angiogenesis, erythropoiesis, and metabolic adaptation. Its high selectivity for PHD2 over other hydroxylases enhances experimental precision. The trihydrate form ensures improved stability and solubility in aqueous solutions, facilitating reproducible in vitro and in vivo studies. Researchers value this compound for its reliable performance in elucidating HIF-dependent mechanisms under hypoxic conditions.
VO-Ohpic trihydrate structure
Product Name:VO-Ohpic trihydrate
CAS No:476310-60-8
MF:C12H16N2O10V
MW:399.204345703125
MDL:MFCD11045907
CID:828913
PubChem ID:329829435
Update Time:2025-05-28
VO-Ohpic trihydrate Chemical and Physical Properties
Names and Identifiers
-
- (OC-6-45) Aqua (3-hydroxy-2-pyridinecarboxylato-kapaN1,kapaO2)[3-(hydroxy-kapaO)-2-pyridinecarboxylato(2-)-kapaO2]oxo-vanadate(1-), hydrogen, trihydrate
- (OC-6-45) Aqua (3-hydroxy-2-pyridinecarboxylato-kapaN1,kapaO2)[3-(hydroxy-kapaO)-2-pyridinecarboxylato(2-)-kapaO2]oxo-vanadat
- VO-OHPIC
- VO-Ohpic trihydrate
- VO Ohpic
- (OC-6-45)-aqua(3-Hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxovanadate(1-) hydrogen trihydrate
- 476310-60-8
- 3-hydroxypyridine-2-carboxylic acid;oxovanadium;trihydrate
- AC-36165
- VO-Ohpic (trihydrate)
-
- MDL： MFCD11045907
- Inchi： 1S/2C6H5NO3.3H2O.O.V/c2*8-4-2-1-3-7-5(4)6(9)10;;;;;/h2*1-3,8H,(H,9,10);3*1H2;;
- InChI Key： RHVLCDIRYQMAQQ-UHFFFAOYSA-N
- SMILES： [V]=O.OC1=CC=CN=C1C(=O)O.OC(C1C(=CC=CN=1)O)=O.O.O.O
Computed Properties
- Exact Mass: 399.024452g/mol
- Monoisotopic Mass: 399.024452g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 5
- Hydrogen Bond Acceptor Count: 12
- Heavy Atom Count: 25
- Rotatable Bond Count: 2
- Complexity: 358
- Covalently-Bonded Unit Count: 6
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 161?2
Experimental Properties
- Solubility: DMSO: >10mg/mL
VO-Ohpic trihydrate Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
VO-Ohpic trihydrate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IT176-100mg |
VO-Ohpic trihydrate |
476310-60-8 | 98+% | 100mg |
2276.0CNY | 2021-07-14 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IT176-10mg |
VO-Ohpic trihydrate |
476310-60-8 | 98+% | 10mg |
1167CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IT176-1mg |
VO-Ohpic trihydrate |
476310-60-8 | 98+% | 1mg |
407CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IT176-50mg |
VO-Ohpic trihydrate |
476310-60-8 | 98+% | 50mg |
3481CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IT176-5mg |
VO-Ohpic trihydrate |
476310-60-8 | 98+% | 5mg |
761CNY | 2021-05-07 | |
| MedChemExpress | HY-13074-10mM*1mLinDMSO |
VO-Ohpic trihydrate |
476310-60-8 | ≥98.0% | 10mM*1mLinDMSO |
￥660 | 2023-07-26 | |
| MedChemExpress | HY-13074-5mg |
VO-Ohpic trihydrate |
476310-60-8 | ≥98.0% | 5mg |
￥600 | 2025-04-16 | |
| MedChemExpress | HY-13074-10mg |
VO-Ohpic trihydrate |
476310-60-8 | ≥98.0% | 10mg |
￥920 | 2025-04-16 | |
| MedChemExpress | HY-13074-50mg |
VO-Ohpic trihydrate |
476310-60-8 | ≥98.0% | 50mg |
￥2744 | 2025-04-16 | |
| MedChemExpress | HY-13074-100mg |
VO-Ohpic trihydrate |
476310-60-8 | ≥98.0% | 100mg |
￥4500 | 2025-04-16 |
VO-Ohpic trihydrate Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:476310-60-8)VO-Ohpic trihydrate
Order Number:A917532
Stock Status:in Stock
Quantity:50mg/100mg/250mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 13:03
Price ($):204.0/305.0/487.0
Email:[email protected]
VO-Ohpic trihydrate Related Literature
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1. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
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Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
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James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
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Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:476310-60-8)VO-Ohpic trihydrate
Purity:99%/99%/99%
Quantity:50mg/100mg/250mg
Price ($):204.0/305.0/487.0