Cas no 456-24-6 (2-Fluoro-5-nitropyridine)
2-Fluoro-5-nitropyridine is a fluorinated nitropyridine derivative widely used as a versatile intermediate in pharmaceutical and agrochemical synthesis. Its key structural features—a fluorine atom at the 2-position and a nitro group at the 5-position—enhance reactivity, making it valuable for nucleophilic aromatic substitution and cross-coupling reactions. The electron-withdrawing nitro group facilitates further functionalization, while the fluorine substituent improves metabolic stability in bioactive compounds. This compound exhibits high purity and consistent performance, ensuring reliable results in research and industrial applications. Its compatibility with diverse reaction conditions makes it a preferred choice for constructing complex heterocyclic frameworks. Proper handling is advised due to its potential sensitivity.
2-Fluoro-5-nitropyridine structure
Product Name:2-Fluoro-5-nitropyridine
CAS No:456-24-6
MF:C5H3FN2O2
MW:142.08792424202
MDL:MFCD03095059
CID:37528
PubChem ID:95264
Update Time:2025-08-05
2-Fluoro-5-nitropyridine Chemical and Physical Properties
Names and Identifiers
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- 2-Fluoro-5-nitropyridine
- 2-Fluor-5-nitro-pyridin
- 2-fluoro-5-nitro-pyridine
- 5-nitro-2-fluoropyridine
- 6-Fluoro-3-nitropyridine
- fluoro-2-nitro-5-pyridine
- PYRIDINE,2-FLUORO-5-NITRO
- PYRIDINE, 2-FLUORO-5-NITRO-
- 2-fluor-5-nitropyridin
- NSC26280
- PubChem1202
- XOZAJNLUAODXSP-UHFFFAOYSA-N
- BCP23147
- STL554512
- FC0266
- BBL100718
- 2-Fluoro-5-nitropyridine, AldrichCPR
- VP1355
- FT-0647780
- AC-5942
- MFCD03095059
- 456-24-6
- SCHEMBL1163154
- DTXSID70196565
- CS-D0968
- NSC-26280
- Q-103368
- AKOS005145591
- AS-14966
- F0983
- AM20051198
- EINECS 207-260-6
- NS00043597
- SY010502
- EN300-104104
- AB13439
- NSC 26280
- AKOS005063588
- A7182
- DB-031387
- DTXCID10119056
- 207-260-6
-
- MDL： MFCD03095059
- Inchi： 1S/C5H3FN2O2/c6-5-2-1-4(3-7-5)8(9)10/h1-3H
- InChI Key： XOZAJNLUAODXSP-UHFFFAOYSA-N
- SMILES： FC1=CC=C(C=N1)[N+](=O)[O-]
Computed Properties
- Exact Mass: 142.01800
- Monoisotopic Mass: 142.018
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 136
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.7
- Topological Polar Surface Area: 58.7
Experimental Properties
- Density: 4,64g/cm
- Melting Point: 18°C(lit.)
- Boiling Point: 87°C/7mmHg(lit.)
- Flash Point: 97.5℃
- Refractive Index: 1.5250
- Water Partition Coefficient: Slightly soluble in water.
- PSA: 58.71000
- LogP: 1.65210
- Sensitiveness: Moisture Sensitive
2-Fluoro-5-nitropyridine Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H302
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazardous Material transportation number：UN 1549
- WGK Germany：3
- Hazard Category Code： 20/21/22-22
- Safety Instruction： S36
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Hazardous Material Identification：
- Storage Condition：Store at room temperature
- Risk Phrases：R20/21/22
2-Fluoro-5-nitropyridine Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-Fluoro-5-nitropyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | F828705-25g |
2-Fluoro-5-nitropyridine |
456-24-6 | 98% | 25g |
￥334.80 | 2022-01-12 | |
| Matrix Scientific | 072864-5g |
2-Fluoro-5-nitropyridine, 95+% |
456-24-6 | 95+% | 5g |
$30.00 | 2023-09-08 | |
| Matrix Scientific | 072864-25g |
2-Fluoro-5-nitropyridine, 95+% |
456-24-6 | 95+% | 25g |
$120.00 | 2023-09-08 | |
| Matrix Scientific | 072864-100g |
2-Fluoro-5-nitropyridine, 95+% |
456-24-6 | 95+% | 100g |
$350.00 | 2023-09-08 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | F0983-25G |
2-Fluoro-5-nitropyridine |
456-24-6 | >98.0%(GC) | 25g |
￥350.00 | 2024-04-16 | |
| TRC | F597683-100mg |
2-Fluoro-5-nitropyridine |
456-24-6 | 100mg |
$64.00 | 2023-05-18 | ||
| TRC | F597683-250mg |
2-Fluoro-5-nitropyridine |
456-24-6 | 250mg |
$75.00 | 2023-05-18 | ||
| TRC | F597683-500mg |
2-Fluoro-5-nitropyridine |
456-24-6 | 500mg |
$87.00 | 2023-05-18 | ||
| TRC | F597683-1g |
2-Fluoro-5-nitropyridine |
456-24-6 | 1g |
$ 80.00 | 2022-06-04 | ||
| ChemScence | CS-D0968-25g |
2-Fluoro-5-nitropyridine |
456-24-6 | 99.70% | 25g |
$40.0 | 2022-04-27 |
2-Fluoro-5-nitropyridine Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:456-24-6)2-Fluoro-5-nitropyridine
Order Number:A7182
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:04
Price ($):355.0
Email:[email protected]
2-Fluoro-5-nitropyridine Related Literature
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1. Nucleophilic displacement reactions in aromatic systems. Part X. Kinetics of the reactions of substituted α-halogenopyridines with aniline, N-methyl-, and N-ethyl-aniline in ethanol or ethyl acetate, and of 1-fluoro-2,4-dinitrobenzene with aniline in various solvents. The influence of basic catalystsDerek M. Brewis,Norman B. Chapman,John S. Paine,John Shorter,David J. Wright J. Chem. Soc. Perkin Trans. 2 1974 1787
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2. Kinetics of some of the reactions of 2-fluoro- and 2-chloro-5-nitropyridines and 1-fluoro- and 1-chloro-2,4-dinitrobenzenes with aniline and piperidine in acetone and methanolT. O. Bamkole,J. Hirst J. Chem. Soc. B 1969 848
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3. Nitro-heteroaromatic derivatives of amino-acids and peptides. Part IV. A circular dichroic method for the selective determination of cysteinyl residuesC. Toniolo,D. Nisato,L. Biondi,A. Signor J. Chem. Soc. Perkin Trans. 1 1972 1182
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Alan R. Katritzky,Eric F. V. Scriven,Suman Majumder,Rena G. Akhmedova,Anatoliy V. Vakulenko,Novruz G. Akhmedov,Ramiah Murugan,Khalil A. Abboud Org. Biomol. Chem. 2005 3 538
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Naya A. Stini,Petros L. Gkizis,Christoforos G. Kokotos Green Chem. 2022 24 6435
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:456-24-6)2-Fluoro-5-nitropyridine
Purity:99%
Quantity:500g
Price ($):355.0