Cas no 453566-94-4 (5-fluoropyridine-2-carboxylic acid hydrochloride)
5-Fluoropyridine-2-carboxylic acid hydrochloride is a fluorinated heterocyclic compound widely used as a key intermediate in pharmaceutical and agrochemical synthesis. Its pyridine core, functionalized with a carboxylic acid group and a fluorine substituent, enhances reactivity and enables selective derivatization. The hydrochloride salt form improves solubility and stability, facilitating handling in synthetic applications. This compound is particularly valuable in medicinal chemistry for the development of bioactive molecules, including enzyme inhibitors and receptor modulators. Its structural features allow for precise modifications, making it a versatile building block for drug discovery and fine chemical production. High purity grades ensure consistent performance in research and industrial processes.
453566-94-4 structure
Product Name:5-fluoropyridine-2-carboxylic acid hydrochloride
CAS No:453566-94-4
MF:C6H5ClFNO2
MW:177.560804128647
CID:3274608
PubChem ID:69360036
Update Time:2025-05-27
5-fluoropyridine-2-carboxylic acid hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 2-PYRIDINECARBOXYLIC ACID, 5-FLUORO-, HYDROCHLORIDE
- DB-398585
- 453566-94-4
- 5-fluoropyridine-2-carboxylic acid;hydrochloride
- 5-fluoropyridine-2-carboxylicacidhydrochloride
- EN300-130922
- 5-fluoropyridine-2-carboxylic acid hydrochloride
- SCHEMBL5223155
- LMBXHNCCBIMEOJ-UHFFFAOYSA-N
- 5-fluoropicolinic acid hydrochloride
- DTA56694
-
- Inchi： 1S/C6H4FNO2.ClH/c7-4-1-2-5(6(9)10)8-3-4;/h1-3H,(H,9,10);1H
- InChI Key： LMBXHNCCBIMEOJ-UHFFFAOYSA-N
- SMILES： Cl.FC1=CN=C(C(=O)O)C=C1
Computed Properties
- Exact Mass: 176.9992843Da
- Monoisotopic Mass: 176.9992843Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 140
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 50.2?2
5-fluoropyridine-2-carboxylic acid hydrochloride Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
5-fluoropyridine-2-carboxylic acid hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-130922-0.05g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 0.05g |
$19.0 | 2023-02-15 | |
| Enamine | EN300-130922-0.1g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 0.1g |
$19.0 | 2023-02-15 | |
| Enamine | EN300-130922-0.25g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 0.25g |
$19.0 | 2023-02-15 | |
| Enamine | EN300-130922-0.5g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 0.5g |
$21.0 | 2023-02-15 | |
| Enamine | EN300-130922-1.0g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 1g |
$0.0 | 2023-06-08 | |
| Enamine | EN300-130922-2.5g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 2.5g |
$38.0 | 2023-02-15 | |
| Enamine | EN300-130922-5.0g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 5.0g |
$66.0 | 2023-02-15 | |
| Enamine | EN300-130922-10.0g |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 95% | 10.0g |
$106.0 | 2023-02-15 | |
| TRC | B440820-100mg |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 100mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B440820-500mg |
5-fluoropyridine-2-carboxylic acid hydrochloride |
453566-94-4 | 500mg |
$ 65.00 | 2022-06-07 |
5-fluoropyridine-2-carboxylic acid hydrochloride Related Literature
-
Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
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Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
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3. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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