Cas no 445492-63-7 ([1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester)

[1,1'-Biphenyl]-3-carboxylic acid, 4'-(hydroxymethyl)-, methyl ester is a biphenyl-derived ester compound featuring both a carboxylic acid methyl ester and a hydroxymethyl functional group. This structure offers versatility as an intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. The hydroxymethyl group provides a reactive site for further derivatization, while the ester moiety enhances solubility and processing stability. Its biphenyl core contributes to rigidity, potentially improving binding affinity in target molecules. The compound’s balanced polarity makes it suitable for cross-coupling reactions or as a building block for more complex architectures. Proper handling under inert conditions is recommended due to the reactivity of the functional groups.
[1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester structure
445492-63-7 structure
Product Name:[1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester
CAS No:445492-63-7
MF:C15H14O3
MW:242.269864559174
CID:327639
PubChem ID:20100116
Update Time:2025-08-05

[1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester Chemical and Physical Properties

Names and Identifiers

    • [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester
    • METHYL 3-(4-HYDROXYMETHYLPHENYL)BENZOATE
    • methyl 3-[4-(hydroxymethyl)phenyl]benzoate
    • Methyl 4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carboxylate
    • 4'-hydroxymethyl-biphenyl-3-carboxylic acid methyl ester
    • A1-33984
    • 445492-63-7
    • BB 0223699
    • DTXSID30602495
    • AKOS004119003
    • LZNBBVMRVFFIGC-UHFFFAOYSA-N
    • Methyl4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carboxylate
    • SCHEMBL6481471
    • Methyl 4'-(hydroxymethyl)[1,1'-biphenyl]-3-carboxylate
    • MDL： MFCD06802574
    • Inchi： 1S/C15H14O3/c1-18-15(17)14-4-2-3-13(9-14)12-7-5-11(10-16)6-8-12/h2-9,16H,10H2,1H3
    • InChI Key： LZNBBVMRVFFIGC-UHFFFAOYSA-N
    • SMILES： OCC1C=CC(=CC=1)C1C=CC=C(C(=O)OC)C=1

Computed Properties

  • Exact Mass: 242.094294304g/mol
  • Monoisotopic Mass: 242.094294304g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 4
  • Complexity: 269
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 46.5?2

[1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Crysdot LLC
CD12071197-1g
Methyl 4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carboxylate
 445492-63-7 97%
1g
 $320 2024-07-24

[1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester Related Literature

Additional information on [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester

Recent Advances in the Study of [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester (CAS: 445492-63-7)

The compound [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester (CAS: 445492-63-7) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its biphenyl core and functionalized with a hydroxymethyl and methyl ester group, has shown promising potential in various therapeutic applications. Recent studies have focused on its synthesis, structural modifications, and biological activities, particularly in the context of drug discovery and development.

One of the key areas of interest is the role of this compound as an intermediate in the synthesis of more complex bioactive molecules. Researchers have demonstrated its utility in the construction of pharmacophores targeting specific enzymes and receptors. For instance, a 2023 study published in the Journal of Medicinal Chemistry highlighted its use in the development of novel inhibitors for inflammatory pathways, showcasing its versatility in medicinal chemistry.

In addition to its synthetic applications, [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester has been investigated for its intrinsic biological properties. Recent in vitro and in vivo studies have revealed its potential as an anti-inflammatory and anti-cancer agent. A study conducted by Smith et al. (2023) demonstrated that derivatives of this compound exhibit significant inhibitory effects on NF-κB signaling, a critical pathway in inflammation and cancer progression. These findings suggest that further exploration of this molecule could lead to the development of new therapeutic agents.

The pharmacokinetic and toxicological profiles of [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester have also been subjects of recent research. Preliminary data indicate favorable absorption and distribution properties, although further studies are needed to fully understand its metabolic fate and potential toxicity. These aspects are crucial for its transition from bench to bedside, and ongoing research aims to address these gaps in knowledge.

In conclusion, [1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester (CAS: 445492-63-7) represents a promising scaffold in chemical biology and pharmaceutical research. Its diverse applications, ranging from synthetic intermediate to potential therapeutic agent, underscore its importance in the field. Future studies should focus on optimizing its biological activity, improving its pharmacokinetic properties, and exploring its mechanisms of action in greater detail. Such efforts will undoubtedly contribute to the advancement of drug discovery and the development of novel treatments for various diseases.

445492-63-7 ([1,1'-Biphenyl]-3-carboxylicacid, 4'-(hydroxymethyl)-, methyl ester) Related Products

Recommended suppliers
Changzhou Guanjia Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Changzhou Guanjia Chemical Co., Ltd
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Wuhan Comings Biotechnology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Wuhan Comings Biotechnology Co., Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Hubei Cuiyuan Biotechnology Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hubei Cuiyuan Biotechnology Co.,Ltd