Cas no 444791-18-8 (1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-)

1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- is a sulfur- and nitrogen-containing heterocyclic compound with potential applications in agrochemical and pharmaceutical research. Its structure features a 1,2,4-thiadiazole core substituted with a chlorophenylmethylsulfonyl group, enhancing its reactivity and binding properties. This compound may serve as a key intermediate in the synthesis of biologically active molecules, particularly those targeting pest control or medicinal chemistry. The presence of chlorine atoms and a sulfonyl group contributes to its stability and potential for selective interactions with biological targets. Its well-defined molecular architecture makes it suitable for further derivatization in specialized chemical synthesis.
1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- structure
444791-18-8 structure
Product Name:1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-
CAS No:444791-18-8
MF:C9H6Cl2N2O2S2
MW:309.192137241364
CID:327547
PubChem ID:2761350
Update Time:2025-10-28

1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- Chemical and Physical Properties

Names and Identifiers

    • 1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-
    • 3-Chloro-5-(3-chlorobenzyl sulphonyl)1,2,4-thiadiazole
    • 3-CHLORO-5-(3-CHLOROBENZYLSULFONYL)-1,2,4-
    • 3-CHLORO-5-(3-CHLOROBENZYLSULFONYL)-1,2,4-THIADIAZOLE
    • 3-chloro-5-[(3-chlorophenyl)methylsulfonyl]-1,2,4-thiadiazole
    • AC1MC4R4
    • AG-F-56143
    • CTK4I8244
    • FT-0644692
    • KB-181695
    • 3-Chloro-5-((3-chlorobenzyl)sulfonyl)-1,2,4-thiadiazole
    • MFCD03068919
    • A826594
    • (S)-(-)-METHYLSUCCINICACIDDIMETHYLESTER
    • 3-Chloro-5-(3-chlorobenzyl sulfonyl)1,2,4-thiadiazole
    • DTXSID60375721
    • 3-chloro-5-[(3-chlorophenyl)methanesulfonyl]-1,2,4-thiadiazole
    • 444791-18-8
    • MDL： MFCD03068919
    • Inchi： 1S/C9H6Cl2N2O2S2/c10-7-3-1-2-6(4-7)5-17(14,15)9-12-8(11)13-16-9/h1-4H,5H2
    • InChI Key： JFKXGMTXATUHTG-UHFFFAOYSA-N
    • SMILES： ClC1=CC=CC(=C1)CS(C1=NC(=NS1)Cl)(=O)=O

Computed Properties

  • Exact Mass: 307.92500
  • Monoisotopic Mass: 307.925
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 3
  • Complexity: 361
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.4
  • Topological Polar Surface Area: 96.5?2

Experimental Properties

  • Density: 1.612
  • Boiling Point: 490.8°C at 760 mmHg
  • Flash Point: 250.6°C
  • Refractive Index: 1.63
  • PSA: 96.54000
  • LogP: 3.89960

1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- Customs Data

  • HS CODE：2934999090
  • Customs Data：

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- Pricemore >>

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1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- Suppliers

Amadis Chemical Company Limited
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(CAS:444791-18-8)1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-
Order Number:A826594
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:11
Price ($):736.0

1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]- Related Literature

Additional information on 1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-

Compound CAS No. 444791-18-8: 1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-

The compound with CAS No. 444791-18-8, commonly referred to as 1,2,4-thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-, is a highly specialized organic sulfur-containing heterocyclic compound. This compound belongs to the class of thiadiazoles, which are well-known for their versatile applications in various fields such as pharmaceuticals, agrochemicals, and materials science. The structure of this compound is characterized by a thiadiazole ring system substituted with a chloro group at position 3 and a sulfonyl group attached to a (3-chlorophenyl)methyl group at position 5. These substituents significantly influence the compound's chemical reactivity, stability, and biological activity.

Recent advancements in synthetic chemistry have enabled the precise synthesis of 1,2,4-thiadiazole derivatives with high purity and yield. Researchers have employed various methodologies, including microwave-assisted synthesis and catalytic processes, to optimize the production of this compound. These methods not only enhance the efficiency of synthesis but also minimize environmental impact by reducing waste and energy consumption. The ability to tailor the substituents on the thiadiazole ring has opened new avenues for exploring its potential in diverse applications.

One of the most promising areas of research involving 1,2,4-thiadiazole derivatives is their application in the development of novel agrochemicals. Studies have shown that this compound exhibits potent antifungal activity against various plant pathogens. Its mechanism of action involves disrupting fungal cell membrane integrity and inhibiting essential enzymatic pathways. Field trials have demonstrated its efficacy in protecting crops from diseases caused by Fusarium and Rhizoctonia species without adverse effects on non-target organisms or the environment.

In the pharmaceutical sector, 1,2,4-thiadiazole derivatives are being investigated for their potential as anticancer agents. Preclinical studies have revealed that these compounds can induce apoptosis in cancer cells by modulating key signaling pathways such as the PI3K/AKT/mTOR pathway. Additionally, their ability to inhibit tumor angiogenesis makes them attractive candidates for combinational therapies with existing chemotherapeutic agents.

The unique electronic properties of 1,2,4-thiadiazole derivatives also make them suitable for applications in materials science. Researchers have explored their use as building blocks for constructing advanced materials such as conductive polymers and metal-organic frameworks (MOFs). These materials exhibit enhanced electrical conductivity and stability under harsh conditions, making them ideal for use in electronic devices and energy storage systems.

From an environmental perspective, the synthesis and application of 1,2,4-thiadiazole derivatives are being optimized to ensure sustainability. Green chemistry principles are being integrated into their production processes to reduce reliance on hazardous solvents and reagents. Life cycle assessments (LCAs) are being conducted to evaluate their environmental footprint from cradle to grave.

In conclusion, 1,2,4-thiadiazole derivatives, particularly CAS No. 444791-18-8 (1,2,4-thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-), represent a versatile class of compounds with wide-ranging applications across multiple industries. Ongoing research continues to uncover new potentials while ensuring their sustainable production and use.

444791-18-8 (1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-) Related Products

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Amadis Chemical Company Limited
(CAS:444791-18-8)1,2,4-Thiadiazole,3-chloro-5-[[(3-chlorophenyl)methyl]sulfonyl]-
A826594
Purity:99%
Quantity:1g
Price ($):736.0
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