• 1. Excited state potential energy surfaces and their interactions in FeIVO active sites
  Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 3. Enantiocontrolled construction of sistodiolynne, an unusual polyketide from the wood-decay fungus Sistrema raduloides
  Chem. Commun., 1997, 767-768
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acid methyl esters
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acid esters Fatty acid methyl esters

Methyl Tetradecanoate-d27 (CAS No. 434349-93-6): An Overview of Its Properties, Applications, and Recent Research

Methyl Tetradecanoate-d27 (CAS No. 434349-93-6) is a deuterated derivative of methyl tetradecanoate, a compound with significant applications in various scientific and industrial fields. This compound is particularly valuable in analytical chemistry and pharmaceutical research due to its stable isotopic labeling, which enhances its detectability and quantification in complex matrices.

Methyl Tetradecanoate-d27 is a member of the class of compounds known as fatty acid methyl esters (FAMEs). These esters are widely used as internal standards in gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) analyses. The deuterium labeling in Methyl Tetradecanoate-d27 provides a distinct advantage over non-labeled counterparts by reducing matrix interference and improving the accuracy of quantitative measurements.

Recent research has highlighted the importance of Methyl Tetradecanoate-d27 in several areas. For instance, a study published in the Journal of Chromatography A demonstrated the utility of deuterated FAMEs, including Methyl Tetradecanoate-d27, in the analysis of lipid profiles in biological samples. The study found that the use of deuterated internal standards significantly improved the precision and reliability of lipid quantification, which is crucial for understanding metabolic pathways and disease mechanisms.

In the pharmaceutical industry, Methyl Tetradecanoate-d27 is employed in the development and quality control of lipid-based drug delivery systems. These systems are designed to enhance the bioavailability and therapeutic efficacy of drugs by encapsulating them within lipid structures. The accurate quantification of lipids using deuterated internal standards like Methyl Tetradecanoate-d27 ensures that these delivery systems meet stringent regulatory requirements.

Beyond its analytical applications, Methyl Tetradecanoate-d27 has also been explored for its potential in environmental monitoring. A study published in the Environmental Science & Technology journal investigated the use of deuterated FAMEs to trace the fate and transport of lipids in environmental samples. The study found that deuterated internal standards provided a robust method for quantifying lipids in complex environmental matrices, which is essential for assessing environmental contamination and ecosystem health.

The synthesis of Methyl Tetradecanoate-d27 involves several steps, including the deuteration of tetradecanoic acid followed by esterification with methanol. The process requires precise control over reaction conditions to ensure high yields and purity. Recent advancements in synthetic chemistry have led to more efficient and cost-effective methods for producing deuterated compounds, making them more accessible for research and industrial applications.

In conclusion, Methyl Tetradecanoate-d27 (CAS No. 434349-93-6) is a valuable compound with a wide range of applications in analytical chemistry, pharmaceutical research, and environmental monitoring. Its stable isotopic labeling provides significant advantages in terms of accuracy and reliability, making it an indispensable tool for researchers and scientists working in these fields. As ongoing research continues to uncover new applications and improve synthetic methods, the importance of compounds like Methyl Tetradecanoate-d27 is likely to grow even further.

• 110-38-3(Ethyl decanoate)
• 106-65-0(Dimethyl succinate)
• 106-79-6(Dimethyl sebacate)
• 106-32-1(Ethyl n-Caprylate)
• 106-02-5(ω-Pentadecalactone)
• 110-42-9(Methyl decanoate)
• 106-30-9(Ethyl Heptanoate(Heptanoic Acid Ethyl Ester))
• 106-33-2(Ethyl Laurate(Ethyl Dodecanoate))
• 109-43-3(dibutyl sebacate)
• 123-29-5(Ethyl nonanoate)