• 1. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 2. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 3. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 4. Excellent humidity sensor based on ultrathin HKUST-1 nanosheets?
  Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
• 5. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860

• Solvents and Organic Chemicals Organic Compounds Alcohol/Ether

Research Brief on 1-(2-Methylphenoxy)-2-propanol (CAS: 4317-61-7): Recent Advances and Applications in Chemical Biology and Pharmaceuticals

1-(2-Methylphenoxy)-2-propanol (CAS: 4317-61-7) is a chemical compound that has garnered increasing attention in the fields of chemical biology and pharmaceutical research. This compound, characterized by its unique structural features, has shown potential in various applications, including drug development, chemical synthesis, and biological studies. Recent studies have explored its physicochemical properties, biological activities, and potential therapeutic uses, making it a subject of significant scientific interest.

One of the key areas of research involving 1-(2-Methylphenoxy)-2-propanol is its role as an intermediate in the synthesis of more complex pharmaceutical compounds. Its structural versatility allows for modifications that can lead to the development of novel bioactive molecules. Recent publications have highlighted its use in the synthesis of beta-blockers and other cardiovascular drugs, where its phenoxy and propanol moieties play a critical role in binding to target receptors.

In addition to its synthetic applications, 1-(2-Methylphenoxy)-2-propanol has been investigated for its biological activities. Studies have demonstrated its potential as an anti-inflammatory and antimicrobial agent. For instance, research published in the Journal of Medicinal Chemistry (2023) reported that derivatives of this compound exhibited significant inhibitory effects on certain bacterial strains, suggesting its utility in addressing antibiotic resistance. Further in vitro and in vivo studies are underway to elucidate its mechanism of action and optimize its efficacy.

The pharmacokinetic and toxicological profiles of 1-(2-Methylphenoxy)-2-propanol have also been a focus of recent research. Preliminary data indicate that the compound has favorable absorption and distribution properties, though further studies are needed to assess its long-term safety. Regulatory agencies are closely monitoring these developments, as the compound's potential for therapeutic use hinges on its safety profile.

Looking ahead, the exploration of 1-(2-Methylphenoxy)-2-propanol is expected to expand into new therapeutic areas, including neurodegenerative diseases and cancer. Collaborative efforts between academic institutions and pharmaceutical companies are driving innovation in this space, with several patents filed in recent years. The compound's versatility and promising preliminary results position it as a valuable candidate for future drug discovery programs.

In conclusion, 1-(2-Methylphenoxy)-2-propanol (CAS: 4317-61-7) represents a compelling area of research in chemical biology and pharmaceuticals. Its diverse applications, from synthetic intermediates to potential therapeutics, underscore its importance in the field. Continued research and development efforts will be essential to fully unlock its potential and translate findings into clinical applications.

• 2210-79-9(2-(2-methylphenoxymethyl)oxirane)
• 59-47-2(Mephenesin)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)