Cas no 425395-73-9 (4-Chloro-6-methylpyrimidine-5-carbonitrile)
4-Chloro-6-methylpyrimidine-5-carbonitrile is a versatile heterocyclic compound featuring a pyrimidine core substituted with chloro, methyl, and cyano functional groups. This structure imparts reactivity suitable for further functionalization, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The chloro group enhances electrophilic substitution potential, while the cyano moiety offers opportunities for nucleophilic addition or cyclization reactions. Its methyl substitution contributes to stability and influences regioselectivity in subsequent transformations. The compound is particularly useful in the preparation of biologically active molecules, including kinase inhibitors and antimicrobial agents. Its well-defined reactivity profile and compatibility with diverse reaction conditions make it a practical choice for medicinal chemistry and material science applications.
425395-73-9 structure
Product Name:4-Chloro-6-methylpyrimidine-5-carbonitrile
CAS No:425395-73-9
MF:C6H4ClN3
MW:153.569059371948
CID:2669889
PubChem ID:17856582
Update Time:2025-06-07
4-Chloro-6-methylpyrimidine-5-carbonitrile Chemical and Physical Properties
Names and Identifiers
-
- 4-CHLORO-5-CYANO-6-METHYLPYRIMIDINE
- 4-chloro-6-methylpyrimidine-5-carbonitrile
- AB54921
- EN300-107598
- Z1198261657
- 868-776-0
- ASA39573
- SCHEMBL1109104
- DB-218848
- AKOS006314917
- 425395-73-9
- 4-Chloro-6-methylpyrimidine-5-carbonitrile
-
- Inchi： 1S/C6H4ClN3/c1-4-5(2-8)6(7)10-3-9-4/h3H,1H3
- InChI Key： DGFULNPICFYUOW-UHFFFAOYSA-N
- SMILES： ClC1=C(C#N)C(C)=NC=N1
Computed Properties
- Exact Mass: 153.0093748 g/mol
- Monoisotopic Mass: 153.0093748 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 162
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.3
- Topological Polar Surface Area: 49.6
- Molecular Weight: 153.57
4-Chloro-6-methylpyrimidine-5-carbonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C991410-5mg |
4-Chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 5mg |
$ 50.00 | 2022-06-06 | ||
| TRC | C991410-10mg |
4-Chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 10mg |
$ 70.00 | 2022-06-06 | ||
| TRC | C991410-50mg |
4-Chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 50mg |
$ 230.00 | 2022-06-06 | ||
| Chemenu | CM520036-1g |
4-Chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 1g |
$815 | 2023-02-02 | |
| Enamine | EN300-107598-0.05g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 0.05g |
$537.0 | 2023-10-28 | |
| Enamine | EN300-107598-0.1g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 0.1g |
$701.0 | 2023-10-28 | |
| Enamine | EN300-107598-0.25g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 0.25g |
$999.0 | 2023-10-28 | |
| Enamine | EN300-107598-0.5g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 0.5g |
$1574.0 | 2023-10-28 | |
| Enamine | EN300-107598-1.0g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 1g |
$2019.0 | 2023-06-10 | |
| Enamine | EN300-107598-2.5g |
4-chloro-6-methylpyrimidine-5-carbonitrile |
425395-73-9 | 95% | 2.5g |
$3957.0 | 2023-10-28 |
4-Chloro-6-methylpyrimidine-5-carbonitrile Related Literature
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
-
Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
-
Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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