Cas no 4160-77-4 (2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl-)
2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- Chemical and Physical Properties
Names and Identifiers
-
- 2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl-
- 3,5-dimethyl-1H-pyrimidine-2,4-dione
- 3,5-Dimethyluracil
- 3,5-Dimethyl-1H-pyrimidin-2,4-dion
- 3-Methylthymine
- N3-methylthymine
- UNII-SS2K4WB6YL
- 3-methyl-thymine
- 3,5-dimethylpyrimidine-2,4(1H,3H)-dione
- DTXSID90194427
- Q27144890
- SCHEMBL221825
- FT-0614708
- 3,5-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- CS-0452393
- AB-323/25048560
- 4160-77-4
- 2,4(1H,3H)-Pyrimidinedione, 3,5-dimethyl-
- NSC 750725
- CHEBI:74766
- SS2K4WB6YL
- NSC750725
- 1-Methylthymin (1. Form)
- NSC-750725
- AKOS006277989
-
- MDL: MFCD02091247
- Inchi: 1S/C6H8N2O2/c1-4-3-7-6(10)8(2)5(4)9/h3H,1-2H3,(H,7,10)
- InChI Key: IIDONYMEGWHGRU-UHFFFAOYSA-N
- SMILES: O=C1C(C)=CNC(N1C)=O
Computed Properties
- Exact Mass: 140.05900
- Monoisotopic Mass: 140.059
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 220
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 49.4A^2
- XLogP3: -0.4
Experimental Properties
- Density: 1.189
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Refractive Index: 1.499
- PSA: 54.86000
- LogP: -0.61800
2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- Customs Data
- HS CODE:2933599090
- Customs Data:
China Customs Code:
2933599090Overview:
2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| eNovation Chemicals LLC | K89898-5g |
3-Methylthymine |
4160-77-4 | 95% | 5g |
$1760 | 2025-02-25 | |
| eNovation Chemicals LLC | K89898-1g |
3-Methylthymine |
4160-77-4 | 95% | 1g |
$850 | 2025-02-25 | |
| eNovation Chemicals LLC | K89898-1g |
3-Methylthymine |
4160-77-4 | 95% | 1g |
$850 | 2024-05-25 | |
| eNovation Chemicals LLC | K89898-5g |
3-Methylthymine |
4160-77-4 | 95% | 5g |
$1760 | 2024-05-25 | |
| eNovation Chemicals LLC | K89898-1g |
3-Methylthymine |
4160-77-4 | 95% | 1g |
$850 | 2025-03-01 | |
| eNovation Chemicals LLC | K89898-5g |
3-Methylthymine |
4160-77-4 | 95% | 5g |
$1760 | 2025-03-01 |
2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- Related Literature
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Priscilla Johnston,Yuki Nishikami,Kei Saito Photochem. Photobiol. Sci. 2014 13 1290
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2. The photochemistry of 1-methylthymine and 3-methylthymineG. M. Blackburn,R. J. H. Davies J. Chem. Soc. C 1966 1342
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3. The photochemistry of 1-methylthymine and 3-methylthymineG. M. Blackburn,R. J. H. Davies J. Chem. Soc. C 1966 1342
-
Lin-Lin Zhou,Hongjiao Xu,Yue Huang,Cai-Guang Yang RSC Chem. Biol. 2021 2 1352
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5. Chapter 12. Nucleic acidsG. M. Blackburn,J. B. Hobbs Annu. Rep. Prog. Chem. Sect. B: Org. Chem. 1985 82 311
Additional information on 2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl-
Comprehensive Overview of 2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- (CAS No. 4160-77-4): Properties, Applications, and Industry Insights
2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl-, with the CAS No. 4160-77-4, is a specialized organic compound belonging to the pyrimidine family. This heterocyclic molecule features a six-membered ring structure with two nitrogen atoms, making it a critical intermediate in pharmaceutical and agrochemical synthesis. Its systematic name, 3,5-dimethyluracil, highlights its structural relationship to uracil, a fundamental component of RNA. The compound's unique properties, such as its solubility in polar solvents and thermal stability, have garnered significant attention in research and industrial applications.
In recent years, the demand for pyrimidine derivatives like 3,5-dimethyluracil has surged due to their versatility in drug development. Researchers are particularly interested in its role as a building block for nucleoside analogs, which are pivotal in antiviral and anticancer therapies. For instance, modifications of the pyrimidinedione core have been explored to enhance bioavailability and target specificity. This aligns with the growing trend of personalized medicine, where tailored molecular designs are crucial for effective treatments.
Beyond pharmaceuticals, CAS No. 4160-77-4 finds applications in agrochemicals, where it serves as a precursor for herbicides and plant growth regulators. The compound's ability to modulate biochemical pathways in plants has made it valuable in sustainable agriculture. With increasing global focus on food security and eco-friendly farming, the agrochemical sector is actively investigating derivatives of 3,5-dimethyl-2,4(1H,3H)-pyrimidinedione to reduce environmental impact while maintaining efficacy.
Synthetic methodologies for 2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- have evolved to prioritize green chemistry principles. Modern techniques, such as microwave-assisted synthesis and catalytic hydrogenation, minimize waste and energy consumption. These advancements resonate with the sustainability goals of the chemical industry, addressing concerns about carbon footprints and resource efficiency. Laboratories and manufacturers are increasingly adopting these methods to meet regulatory standards and consumer expectations.
Analytical characterization of CAS No. 4160-77-4 involves advanced techniques like HPLC, NMR spectroscopy, and mass spectrometry. These tools ensure purity and consistency, which are critical for compliance with Good Manufacturing Practices (GMP). The compound's stability under various pH and temperature conditions further underscores its reliability in industrial processes. Such data is often sought by quality control professionals and formulation scientists.
Market trends indicate a steady rise in the procurement of 3,5-dimethyluracil, driven by its expanding applications. Suppliers and distributors emphasize batch-to-batch consistency and supply chain transparency to cater to pharmaceutical and agrochemical clients. Additionally, the compound's compatibility with biodegradable formulations aligns with the shift toward circular economy models in chemical manufacturing.
In conclusion, 2,4(1H,3H)-Pyrimidinedione,3,5-dimethyl- (CAS No. 4160-77-4) exemplifies the intersection of innovation and practicality in modern chemistry. Its multifaceted roles in therapeutics, agriculture, and sustainable synthesis make it a compound of enduring relevance. As research continues to uncover new derivatives and applications, this pyrimidine derivative will likely remain a cornerstone of interdisciplinary scientific progress.
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