• 1. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 2. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 3. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 4. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 5. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

3-Amino-3-(2,4-Difluorophenyl)Propanoic Acid (CAS No: 412925-23-6)

3-Amino-3-(2,4-difluorophenyl)propanoic acid is a compound with the CAS registry number 412925-23-6. This compound is a derivative of propanoic acid, featuring a substituted amino group and a fluorinated aromatic ring. The presence of the amino group and the fluorine atoms on the phenyl ring introduces unique chemical properties, making this compound a subject of interest in various research fields, particularly in drug discovery and organic synthesis.

The structure of 3-amino-3-(2,4-difluorophenyl)propanoic acid consists of a central propanoic acid backbone with an amino group attached to the third carbon. The phenyl ring is substituted at the 2 and 4 positions with fluorine atoms, which are known to enhance the lipophilicity and bioavailability of compounds. This substitution pattern also contributes to the compound's stability and reactivity in different chemical environments.

Recent studies have highlighted the potential of 3-amino-3-(2,4-difluorophenyl)propanoic acid in the development of novel therapeutic agents. Researchers have explored its role as a building block for constructing bioactive molecules, particularly in the context of medicinal chemistry. The amino group can act as a nucleophile in various reactions, enabling the synthesis of complex structures with desired pharmacological properties.

In terms of biological activity, 3-amino-3-(2,4-difluorophenyl)propanoic acid has shown promise in modulating enzyme activity and receptor binding. For instance, it has been investigated as a potential inhibitor of certain kinases and proteases, which are key targets in treating diseases such as cancer and inflammatory disorders. The fluorine atoms on the phenyl ring enhance the molecule's ability to interact with biological systems, making it a valuable tool in drug design.

The synthesis of 3-amino-3-(2,4-difluorophenyl)propanoic acid involves multi-step organic reactions. One common approach includes the coupling of an amino alcohol with a fluorinated aromatic aldehyde or ketone, followed by oxidation to form the carboxylic acid group. Researchers have optimized these reactions to achieve high yields and purity levels, ensuring that the compound meets rigorous quality standards for use in preclinical studies.

From an environmental perspective, 3-amino-3-(2,4-difluorophenyl)propanoic acid exhibits moderate biodegradability under aerobic conditions. However, its persistence in aquatic environments remains a topic of interest for eco-toxicological assessments. Regulatory agencies have established guidelines for handling and disposing of this compound to minimize its impact on ecosystems.

In conclusion, 3-amino-3-(2,4-difluorophenyl)propanoic acid (CAS No: 412925-23-6) is a versatile compound with significant potential in pharmaceutical research and development. Its unique structure and functional groups make it an attractive candidate for designing bioactive molecules with therapeutic applications. As research continues to uncover its full spectrum of properties and uses, this compound is expected to play an increasingly important role in advancing medical science.

• 151911-32-9((S)-3-Amino-3-(2-fluoro-phenyl)-propionic acid)
• 1354970-73-2((3S)-3-Amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride)
• 117391-49-8(3-Amino-3-(2-fluorophenyl)propanoic Acid)
• 151911-22-7((R)-3-Amino-3-(2-fluoro-phenyl)-propionic acid)
• 1354970-81-2((3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride)
• 1270156-95-0((3S)-3-Amino-3-(2,6-difluorophenyl)propanoic acid)
• 612532-16-8((3S)-3-Amino-3-(2,4-difluorophenyl)propanoic acid)
• 1228561-26-9((3R)-3-Amino-3-(2,5-difluorophenyl)propanoic acid)
• 773126-27-5(3-AMINO-3-(2-FLUORO-5-METHYLPHENYL)PROPANOIC ACID)
• 612532-20-4( )