Cas no 1354970-81-2 ((3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride)
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride
- (R)-3-Amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride
- Z1696822760
- 1354970-81-2
- AKOS030626965
- (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid;hydrochloride
- F76918
- (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid HCl
- CS-0263204
- EN300-85542
- (R)-3-Amino-3-(2,4-difluorophenyl)propanoicacidhydrochloride
- BS-51835
-
- MDL: MFCD20233626
- Inchi: 1S/C9H9F2NO2.ClH/c10-5-1-2-6(7(11)3-5)8(12)4-9(13)14;/h1-3,8H,4,12H2,(H,13,14);1H/t8-;/m1./s1
- InChI Key: DDIRKYUVUCHBNJ-DDWIOCJRSA-N
- SMILES: [C@@H](C1C=CC(F)=CC=1F)(N)CC(=O)O.Cl
Computed Properties
- Exact Mass: 237.0368126g/mol
- Monoisotopic Mass: 237.0368126g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 15
- Rotatable Bond Count: 3
- Complexity: 213
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 63.3?2
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | R111090-10mg |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 10mg |
$ 70.00 | 2022-06-03 | ||
| TRC | R111090-50mg |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 50mg |
$ 210.00 | 2022-06-03 | ||
| TRC | R111090-100mg |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 100mg |
$ 340.00 | 2022-06-03 | ||
| eNovation Chemicals LLC | Y1230842-1g |
(R)-3-Amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 1g |
$1000 | 2024-06-03 | |
| Enamine | EN300-85542-0.05g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 0.05g |
$235.0 | 2023-09-02 | |
| Enamine | EN300-85542-0.1g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 0.1g |
$352.0 | 2023-09-02 | |
| Enamine | EN300-85542-0.25g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 0.25g |
$503.0 | 2023-09-02 | |
| Enamine | EN300-85542-0.5g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 0.5g |
$791.0 | 2023-09-02 | |
| Enamine | EN300-85542-1.0g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 1.0g |
$1014.0 | 2023-02-11 | |
| Enamine | EN300-85542-2.5g |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride |
1354970-81-2 | 95% | 2.5g |
$1988.0 | 2023-09-02 |
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride Related Literature
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Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
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Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
Additional information on (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride
Introduction to (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride (CAS No. 1354970-81-2)
(3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride is a specialized organic compound that has garnered significant attention in the field of pharmaceutical research and development. With a CAS number of 1354970-81-2, this compound represents a crucial intermediate in the synthesis of various biologically active molecules. Its unique structural features, particularly the presence of a chiral center and fluorinated aromatic groups, make it a valuable building block for designing novel therapeutic agents.
The< strong>hydrochloride salt form of this compound enhances its solubility and stability, making it more suitable for various applications in medicinal chemistry. The< strong>amino group and the< strong>carboxylic acid moiety provide reactive sites for further functionalization, enabling the construction of complex molecular architectures. These properties have positioned this compound as a key candidate in the development of drugs targeting a wide range of diseases.
In recent years, there has been growing interest in the use of fluorinated aromatic compounds in drug design due to their enhanced metabolic stability and improved binding affinity to biological targets. The< strong>2,4-difluorophenyl group in (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride contributes to these advantages by increasing the lipophilicity and electronic characteristics of the molecule. This has been particularly beneficial in the development of kinase inhibitors and other small-molecule drugs.
Recent studies have highlighted the potential of this compound in the treatment of cancer and inflammatory diseases. For instance, researchers have demonstrated that derivatives of this molecule can inhibit the activity of specific enzymes involved in tumor growth and progression. The chiral center at the third position adds another layer of complexity, allowing for the exploration of enantiomeric effects that can significantly influence biological activity.
The< strong>pharmaceutical industry has recognized the importance of intermediates like (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride due to their versatility and efficacy. Pharmaceutical companies are increasingly investing in research to optimize synthetic routes and improve yields for such compounds. This trend is driven by the need for more effective and targeted therapies, as well as the desire to reduce costs associated with drug development.
The< strong>synthesis of this compound involves multi-step organic reactions that require precise control over reaction conditions. Advanced techniques such as asymmetric synthesis are often employed to achieve high enantiomeric purity. The use of catalysts like transition metals has also been explored to enhance reaction efficiency and selectivity. These advancements have made it possible to produce larger quantities of this compound for industrial applications.
In addition to its applications in drug development, (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride has potential uses in materials science and agrochemicals. The unique structural features of this molecule make it a promising candidate for designing novel materials with specific properties. Furthermore, its derivatives could be explored as bioactive agents in crop protection applications.
The< strong>cas no 1354970-81-2 designation ensures that researchers can reliably identify and purchase this compound from chemical suppliers. Regulatory agencies require such identifiers to maintain consistency and safety in chemical commerce. The availability of high-quality reference materials with precise CAS numbers is essential for ensuring reproducibility in scientific research.
The future prospects for (3R)-3-amino-3-(2,4-difluorophenyl)propanoic acid hydrochloride are promising, with ongoing research aimed at expanding its applications and improving its synthesis methods. Collaborative efforts between academia and industry are likely to drive innovation in this field, leading to new breakthroughs in drug discovery and material science. As our understanding of biological systems continues to grow, compounds like this will play an increasingly important role in addressing complex challenges in medicine and technology.
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