Cas no 4103-60-0 (Benzeneacetamide, 2-amino-)

Benzeneacetamide, 2-amino-, is a chemical compound characterized by the presence of an amino group attached to the benzeneacetamide structure. This functional group imparts reactivity, making it a valuable intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals. Its aromatic backbone ensures stability, while the amino group enables further derivatization, such as acylation or alkylation. The compound is often utilized in the preparation of active pharmaceutical ingredients (APIs) and fine chemicals due to its versatile reactivity and compatibility with various reaction conditions. Proper handling and storage are essential to maintain its integrity, as the amino group may be sensitive to oxidation or moisture under certain conditions.
Benzeneacetamide, 2-amino- structure
Benzeneacetamide, 2-amino- structure
Product Name:Benzeneacetamide, 2-amino-
CAS No:4103-60-0
MF:C8H10N2O
MW:150.177801609039
CID:334688
PubChem ID:278286
Update Time:2025-06-14

Benzeneacetamide, 2-amino- Chemical and Physical Properties

Names and Identifiers

    • Benzeneacetamide, 2-amino-
    • 2-(2-aminophenyl)acetamide
    • 2-AMINOPHENYLACETAMIDE
    • benzeneacetamide,2-amino
    • AB26281
    • DTXSID30299041
    • (2-carbamoylmethyl-phenyl)-amine
    • SCHEMBL1039164
    • a-aminophenylacetamide
    • TXMURLRUEUBDHN-UHFFFAOYSA-N
    • EN300-35913
    • CS-0216183
    • Z239125326
    • NSC127700
    • NSC-127700
    • 2-aminophenylacetamide, AldrichCPR
    • D78598
    • 4103-60-0
    • AKOS000130385
    • Inchi: 1S/C8H10N2O/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5,9H2,(H2,10,11)
    • InChI Key: TXMURLRUEUBDHN-UHFFFAOYSA-N
    • SMILES: O=C(CC1C=CC=CC=1N)N

Computed Properties

  • Exact Mass: 150.07900
  • Monoisotopic Mass: 150.079
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 147
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 69.1?2

Experimental Properties

  • Density: 1.198
  • Boiling Point: 399.6°Cat760mmHg
  • Flash Point: 195.5°C
  • Refractive Index: 1.612
  • PSA: 69.11000
  • LogP: 1.57810

Benzeneacetamide, 2-amino- Security Information

  • Hazard Category Code: 43
  • Safety Instruction: 36/37

Benzeneacetamide, 2-amino- Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Benzeneacetamide, 2-amino- Pricemore >>

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Benzeneacetamide, 2-amino- Related Literature

Additional information on Benzeneacetamide, 2-amino-

Comprehensive Overview of Benzeneacetamide, 2-amino- (CAS No. 4103-60-0): Properties, Applications, and Industry Insights

Benzeneacetamide, 2-amino- (CAS No. 4103-60-0), a specialized organic compound, has garnered significant attention in pharmaceutical and chemical research due to its unique structural properties. This aromatic amide derivative, characterized by an amino group at the ortho position of the benzene ring, serves as a versatile intermediate in synthetic chemistry. Its molecular formula, C8H10N2O, and precise CAS registry number make it a distinguishable entity in chemical databases, facilitating its traceability in industrial and academic settings.

In recent years, the demand for 2-amino benzeneacetamide has surged, driven by its role in the synthesis of bioactive molecules. Researchers highlight its utility in constructing heterocyclic frameworks, which are pivotal in drug discovery for treating neurological and metabolic disorders. The compound’s amino-functionalized benzene ring enables selective modifications, aligning with modern trends in green chemistry and sustainable synthesis—topics frequently searched in scientific forums and AI-driven platforms like Google Scholar and PubMed.

From a technical perspective, Benzeneacetamide, 2-amino- exhibits a melting point range of 145–150°C and moderate solubility in polar solvents, making it suitable for controlled reactions. Analytical techniques such as HPLC and NMR are commonly employed to verify its purity, a critical factor for applications in high-value pharmaceuticals. Industry reports indicate its growing use in precursor synthesis for APIs (Active Pharmaceutical Ingredients), particularly in oncology and CNS (Central Nervous System) therapeutics—areas dominating current biomedical discussions.

Environmental and regulatory considerations further shape the discourse around CAS No. 4103-60-0. While not classified as hazardous under major safety frameworks, its handling requires adherence to standard laboratory protocols. This aligns with the broader public interest in chemical safety data sheets (SDS) and eco-friendly manufacturing, as reflected in search engine analytics. Companies leveraging this compound increasingly adopt closed-loop processes to minimize waste, responding to the global push for circular economy practices.

Innovations in catalytic methods have further optimized the production of 2-amino benzeneacetamide, reducing energy consumption and byproduct formation. Patent filings reveal novel routes involving enzymatic catalysis and flow chemistry—keywords trending in AI-curated research summaries. Such advancements address the dual demand for cost efficiency and scalability, key concerns for manufacturers navigating supply chain disruptions post-pandemic.

Market analysts project steady growth for Benzeneacetamide, 2-amino-, citing its irreplaceability in niche segments like peptide mimetics and small-molecule probes. Educational content around its structure-activity relationships (SAR) also sees high engagement, underscoring the compound’s pedagogical value in medicinal chemistry courses. As AI tools democratize access to chemical data, queries combining CAS 4103-60-0 with synthetic protocols or spectroscopic data have spiked, reflecting a shift toward self-driven research among professionals.

In conclusion, Benzeneacetamide, 2-amino- exemplifies the intersection of traditional organic chemistry and cutting-edge applications. Its adaptability to emerging technologies and alignment with sustainability goals ensure its relevance in future scientific endeavors. For stakeholders, staying abreast of its evolving applications—from drug development to material science—is essential to capitalize on its potential.

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