Cas no 4053-36-5 (8-Methylquinolin-2(1H)-one)
8-Methylquinolin-2(1H)-one Chemical and Physical Properties
Names and Identifiers
-
- 8-Methylquinolin-2(1H)-one
- 8-Methyl-2(1H)-quinolinone
- 2-Hydroxy-8-methylquinoline
- 8-methyl-1H-quinolin-2-one
- 2(1H)-Quinolinone, 8-methyl-
- 8-methyl-2-quinolone
- 8-Methylcarbostyril
- 2-Hydroxy-8-methyl-chinolin
- XXPVCQMOIBCSDT-UHFFFAOYSA-N
- 8-methyl-1,2-dihydroquinolin-2-one
- SY021046
- V5800
- Q27121424
- EN300-625027
- CS-0187288
- DTXSID60415994
- AS-32441
- InChI=1/C10H9NO/c1-7-3-2-4-8-5-6-9(12)11-10(7)8/h2-6H,1H3,(H,11,12
- DB-360037
- CHEBI:48989
- SB67880
- 4053-36-5
- MFCD13195790
- AKOS013465675
- SCHEMBL433883
- 8-METHYLQUINOLIN-2-OL
-
- MDL: MFCD13195790
- Inchi: 1S/C10H9NO/c1-7-3-2-4-8-5-6-9(12)11-10(7)8/h2-6H,1H3,(H,11,12)
- InChI Key: XXPVCQMOIBCSDT-UHFFFAOYSA-N
- SMILES: O=C1C=CC2C=CC=C(C)C=2N1
Computed Properties
- Exact Mass: 159.06800
- Monoisotopic Mass: 159.068413911g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 12
- Rotatable Bond Count: 0
- Complexity: 222
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 29.1
- XLogP3: 1.7
Experimental Properties
- Boiling Point: 339.3±42.0℃ at 760mmHg
- PSA: 33.12000
- LogP: 2.24880
8-Methylquinolin-2(1H)-one Customs Data
- HS CODE:2933499090
- Customs Data:
China Customs Code:
2933499090Overview:
2933499090. Other compounds containing quinoline or isoquinoline ring system [but not further fused]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
8-Methylquinolin-2(1H)-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A189006843-5g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 5g |
$374.40 | 2023-09-02 | |
| Alichem | A189006843-10g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 10g |
$743.60 | 2023-09-02 | |
| Alichem | A189006843-25g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 25g |
$1040.40 | 2023-09-02 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MD586-1g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 97% | 1g |
261.0CNY | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MD586-5g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 97% | 5g |
1049.0CNY | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-MD586-200mg |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 97% | 200mg |
96.0CNY | 2021-08-05 | |
| Chemenu | CM144948-5g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 5g |
$337 | 2021-08-05 | |
| Chemenu | CM144948-10g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 10g |
$669 | 2021-08-05 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D852289-250mg |
8-Methyl-2(1H)-quinolinone |
4053-36-5 | ≥95% | 250mg |
348.30 | 2021-05-17 | |
| Fluorochem | 216065-1g |
8-Methylquinolin-2(1H)-one |
4053-36-5 | 95% | 1g |
£117.00 | 2022-03-01 |
8-Methylquinolin-2(1H)-one Related Literature
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Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
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Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
Additional information on 8-Methylquinolin-2(1H)-one
Exploring the Versatile Applications and Properties of 8-Methylquinolin-2(1H)-one (CAS No. 4053-36-5)
8-Methylquinolin-2(1H)-one (CAS No. 4053-36-5) is a fascinating heterocyclic compound that has garnered significant attention in the fields of organic chemistry, pharmaceuticals, and material science. This compound, also known as 8-methyl-2-quinolone, belongs to the quinoline family, which is renowned for its diverse biological activities and industrial applications. The unique structural features of 8-Methylquinolin-2(1H)-one make it a valuable intermediate in the synthesis of more complex molecules, particularly in drug discovery and development.
One of the most intriguing aspects of 8-Methylquinolin-2(1H)-one is its molecular structure, which combines a quinoline backbone with a methyl group at the 8-position and a ketone functionality at the 2-position. This arrangement imparts distinct chemical properties, such as enhanced stability and reactivity, which are highly sought after in synthetic chemistry. Researchers have explored its potential as a building block for pharmaceutical intermediates, owing to its ability to participate in various coupling reactions and functional group transformations.
In recent years, the demand for 8-Methylquinolin-2(1H)-one has surged due to its role in the development of novel therapeutic agents. For instance, quinoline derivatives are frequently investigated for their antimicrobial, anticancer, and anti-inflammatory properties. The 8-methyl-2-quinolone scaffold, in particular, has shown promise in modulating biological pathways, making it a focal point for medicinal chemists. This aligns with the growing trend of targeting heterocyclic compounds for drug design, as highlighted by numerous publications and patents.
Beyond pharmaceuticals, 8-Methylquinolin-2(1H)-one finds applications in material science, where its photophysical properties are exploited for developing organic light-emitting diodes (OLEDs) and fluorescent probes. The compound’s ability to absorb and emit light at specific wavelengths makes it a candidate for advanced materials used in sensors and optoelectronic devices. This versatility has sparked interest among researchers working on sustainable and high-performance materials, a topic that resonates with current environmental and technological trends.
The synthesis of 8-Methylquinolin-2(1H)-one typically involves multi-step organic reactions, starting from readily available precursors like aniline derivatives. Modern synthetic routes emphasize efficiency and green chemistry principles, such as catalytic methods and solvent-free conditions, to minimize environmental impact. These advancements address the increasing consumer and regulatory focus on sustainable chemistry, a hot topic in both academic and industrial circles.
From a commercial perspective, 8-Methylquinolin-2(1H)-one is supplied by specialized chemical manufacturers and distributors catering to research institutions and pharmaceutical companies. Its market dynamics are influenced by factors like R&D investments, patent expirations, and the emergence of new applications. For buyers, key considerations include purity, scalability, and compliance with regulatory standards, which are frequently searched topics in procurement databases.
In summary, 8-Methylquinolin-2(1H)-one (CAS No. 4053-36-5) is a multifaceted compound with significant potential across multiple industries. Its structural elegance, combined with its applicability in drug discovery and material science, ensures its continued relevance in scientific research. As the demand for innovative and sustainable chemical solutions grows, compounds like 8-methyl-2-quinolone will undoubtedly remain at the forefront of scientific and industrial advancements.
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