Cas no 39028-27-8 (N-Succinimidyl Iodoacetate (~80%))

N-Succinimidyl Iodoacetate (~80%) is a heterobifunctional crosslinking reagent commonly used in bioconjugation applications. The compound features an NHS ester group, enabling efficient amine-reactive coupling, and an iodoacetyl moiety, which selectively reacts with thiol groups under mild conditions. This dual functionality facilitates the site-specific modification of proteins, peptides, and other biomolecules, making it valuable for labeling, immobilization, and crosslinking studies. The iodoacetyl group offers enhanced stability compared to maleimide-based reagents, reducing unwanted side reactions. With ~80% purity, the product is suitable for controlled conjugation workflows where precise reactivity is required. Its compatibility with aqueous buffers and organic solvents further enhances its utility in diverse biochemical and biotechnological applications.
N-Succinimidyl Iodoacetate (~80%) structure
39028-27-8 structure
Product Name:N-Succinimidyl Iodoacetate (~80%)
CAS No:39028-27-8
MF:C6H6INO4
MW:283.020614147186
MDL:MFCD00058451
CID:293344
PubChem ID:125307234
Update Time:2025-10-24

N-Succinimidyl Iodoacetate (~80%) Chemical and Physical Properties

Names and Identifiers

    • 2,5-Dioxopyrrolidin-1-yl 2-iodoacetate
    • N-Succinimidyl Iodoacetate
    • Iodoacetic Acid N-Hydroxysuccinimide Ester
    • (2,5-dioxopyrrolidin-1-yl) 2-iodoacetate
    • Aceticacid, 2-iodo-, 2,5-dioxo-1-pyrrolidinyl ester
    • N-Hydroxysuccinimidyl Iodoacetate
    • N-Succinimidyl Iodoa
    • (SIA)
    • Iodoacetic Acid N-Succinimidyl Ester
    • N-(Iodoacetoxy)succinimide
    • N-Succinimidyl iodoacetate(SIA)
    • Succinimidyl iodoacetate
    • N-Succinimidyl Iodoacetate (~80%)
    • MDL： MFCD00058451
    • Inchi： 1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
    • InChI Key： VRDGQQTWSGDXCU-UHFFFAOYSA-N
    • SMILES： ICC(=O)ON1C(CCC1=O)=O

Computed Properties

  • Exact Mass: 282.93400
  • Monoisotopic Mass: 282.934
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 3
  • Complexity: 224
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 63.7A^2

Experimental Properties

  • Color/Form: White solid
  • Density: 2.11
  • Melting Point: 146.0 to 150.0 deg-C
  • Boiling Point: 315.6±44.0℃ at 760 mmHg
  • Flash Point: 315.6 °C at 760 mmHg
  • Refractive Index: 1.614
  • Solubility: DMF: 50?mg/mL
  • PSA: 63.68000
  • LogP: -0.03350
  • Sensitiveness: Sensitive to heat and humidity

N-Succinimidyl Iodoacetate (~80%) Security Information

N-Succinimidyl Iodoacetate (~80%) Customs Data

  • HS CODE：2925190090
  • Customs Data：

    China Customs Code:

    2925190090

    Overview:

    2925190090 Other imides and their derivative salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

N-Succinimidyl Iodoacetate (~80%) Pricemore >>

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N-Succinimidyl Iodoacetate (~80%) Production Method

N-Succinimidyl Iodoacetate (~80%) Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:39028-27-8)IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
Order Number:LE5729
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:48
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:39028-27-8)N-Succinimidyl Iodoacetate (~80%)
Order Number:A6557
Stock Status:in Stock
Quantity:5g/1g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:04
Price ($):1094.0/312.0

N-Succinimidyl Iodoacetate (~80%) Related Literature

Related Categories

39028-27-8 (N-Succinimidyl Iodoacetate (~80%)) Related Products

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:39028-27-8)IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
LE5729
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email
Amadis Chemical Company Limited
(CAS:39028-27-8)N-Succinimidyl Iodoacetate (~80%)
A6557
Purity:99%/99%
Quantity:5g/1g
Price ($):1094.0/312.0
Email