• 1. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 2. Evolution and characterization of a benzylguanine-binding RNA aptamer?
  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
• 3. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 4. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 5. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls N-acyl amines
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty amides N-acyl amines

N,N-Dimethylhexadecanamide (CAS No. 3886-91-7): An Overview of Its Properties, Applications, and Recent Research

N,N-Dimethylhexadecanamide (CAS No. 3886-91-7) is a long-chain fatty amide that has gained significant attention in various scientific and industrial applications. This compound, also known as N,N-dimethylpalmitamide or 16-dimethylamido-hexadecane, is characterized by its unique chemical structure and versatile properties, making it a valuable component in numerous fields, including pharmaceuticals, cosmetics, and materials science.

The molecular formula of N,N-Dimethylhexadecanamide is C18H37NO, and its molecular weight is approximately 287.49 g/mol. The compound is a white to off-white crystalline solid at room temperature and is insoluble in water but soluble in organic solvents such as ethanol and chloroform. These physical properties make it suitable for a wide range of applications where solubility and stability are critical factors.

In the pharmaceutical industry, N,N-Dimethylhexadecanamide has been explored for its potential as a drug delivery agent. Recent studies have shown that this compound can enhance the permeability of biological membranes, thereby improving the bioavailability of poorly soluble drugs. For instance, a study published in the Journal of Pharmaceutical Sciences demonstrated that N,N-Dimethylhexadecanamide can significantly increase the transdermal absorption of certain therapeutic agents, making it a promising candidate for transdermal drug delivery systems.

Beyond its pharmaceutical applications, N,N-Dimethylhexadecanamide has also found use in the cosmetics industry. Its emollient properties and ability to form stable emulsions make it an effective ingredient in skin care products. A recent review in the International Journal of Cosmetic Science highlighted the compound's role in enhancing the moisturizing and conditioning effects of cosmetic formulations, contributing to improved skin hydration and texture.

In materials science, N,N-Dimethylhexadecanamide has been investigated for its potential as a lubricant and surfactant. Its long hydrocarbon chain provides excellent lubricating properties, while its amide functional group enhances surface activity. This dual functionality makes it suitable for use in various industrial processes, such as metalworking fluids and lubricating oils. A study published in the Journal of Surfactants and Detergents reported that N,N-Dimethylhexadecanamide can effectively reduce friction and wear in mechanical systems, leading to improved performance and longer equipment life.

The environmental impact of N,N-Dimethylhexadecanamide has also been a subject of recent research. Studies have shown that this compound exhibits low toxicity and biodegradability, making it an environmentally friendly alternative to traditional surfactants and emulsifiers. A report in the Journal of Environmental Science and Health highlighted the compound's minimal ecological footprint and potential for sustainable use in various applications.

In conclusion, N,N-Dimethylhexadecanamide (CAS No. 3886-91-7) is a multifunctional compound with a wide range of applications across different industries. Its unique chemical structure and favorable properties make it an attractive choice for drug delivery systems, cosmetic formulations, lubricants, and surfactants. Ongoing research continues to uncover new possibilities for this versatile compound, further solidifying its importance in both scientific and industrial contexts.

• 381230-85-9(Pentanamide,N,N-dimethyl-5-oxo-)
• 5830-30-8(N,N-Dimethylhexanamide)
• 13424-87-8(Nonanediamide,N1,N1,N9,N9-tetramethyl-)
• 13424-83-4(Decanediamide,N1,N1,N10,N10-tetramethyl-)
• 13424-80-1(Pentanediamide,N1,N1,N5,N5-tetramethyl-)
• 1115-96-4(NN-Dimethylpimelamide)
• 1118-92-9(N,N-Dimethylcaprylamide)
• 14433-76-2(N,N-Dimethyldecanamide)
• 3007-53-2(N,N-Dimethyldodecanamide)
• 27397-05-3(Octanediamide,N1,N1,N8,N8-tetramethyl-)