Cas no 388582-41-0 (4-Amino-6-hydroxy-2-methylpyrimidine dihydrate)

4-Amino-6-hydroxy-2-methylpyrimidine dihydrate is a crystalline pyrimidine derivative with the molecular formula C5H7N3O·2H2O. This compound serves as a versatile intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its dihydrate form enhances stability and solubility, making it suitable for controlled reactions. The presence of both amino and hydroxy functional groups allows for selective modifications, enabling its use in heterocyclic chemistry and nucleoside analog synthesis. With a well-defined structure and high purity, it ensures reproducibility in research and industrial applications. Its compatibility with aqueous and organic solvents further broadens its utility in synthetic pathways.
4-Amino-6-hydroxy-2-methylpyrimidine dihydrate structure
388582-41-0 structure
Product Name:4-Amino-6-hydroxy-2-methylpyrimidine dihydrate
CAS No:388582-41-0
MF:C5H11N3O3
MW:161.159140825272
MDL:MFCD00150311
CID:92836
PubChem ID:135472948
Update Time:2025-06-15

4-Amino-6-hydroxy-2-methylpyrimidine dihydrate Chemical and Physical Properties

Names and Identifiers

    • 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate
    • 6-amino-2-methyl-1H-pyrimidin-4-one,dihydrate
    • ST50405409
    • E79079
    • 6-Amino-2-methylpyrimidin-4-oldihydrate
    • 388582-41-0
    • AKOS015892471
    • 6-Amino-2-methylpyrimidin-4(3H)-one dihydrate
    • DTXSID70369217
    • CS-0132431
    • AS-64790
    • MFCD00150311
    • 6-Amino-2-methylpyrimidin-4-ol dihydrate
    • SB56938
    • 4-amino-2-methyl-1H-pyrimidin-6-one;dihydrate
    • 6-amino-2-methyl-3H-pyrimidin-4-one dihydrate
    • MDL: MFCD00150311
    • Inchi: 1S/C5H7N3O.2H2O/c1-3-7-4(6)2-5(9)8-3;;/h2H,1H3,(H3,6,7,8,9);2*1H2
    • InChI Key: QJZWHXSXVBZLJI-UHFFFAOYSA-N
    • SMILES: O=C1C=C(N)N=C(C)N1.O.O
    • BRN: 118273

Computed Properties

  • Exact Mass: 161.08000
  • Monoisotopic Mass: 161.08004122g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 204
  • Covalently-Bonded Unit Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 9
  • XLogP3: nothing
  • Topological Polar Surface Area: 69.5?2

Experimental Properties

  • Color/Form: White or cream powder
  • Melting Point: >300°C
  • PSA: 90.49000
  • LogP: 0.52540
  • Solubility: Soluble in water

4-Amino-6-hydroxy-2-methylpyrimidine dihydrate Security Information

  • Safety Instruction: S24/25
  • TSCA:Yes
  • Safety Term:S24/25

4-Amino-6-hydroxy-2-methylpyrimidine dihydrate Customs Data

  • HS CODE:2933599090
  • Customs Data:

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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4-Amino-6-hydroxy-2-methylpyrimidine dihydrate Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:388582-41-0)4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE DIHYDRATE
Order Number:sfd8142
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally

Additional information on 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate

Comprehensive Overview of 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate (CAS No. 388582-41-0)

4-Amino-6-hydroxy-2-methylpyrimidine dihydrate (CAS No. 388582-41-0) is a versatile organic compound widely utilized in pharmaceutical research, agrochemical development, and material science. This pyrimidine derivative has garnered significant attention due to its unique chemical properties and potential applications in drug synthesis. With the increasing demand for heterocyclic compounds in modern chemistry, this substance has become a focal point for researchers exploring novel bioactive molecules and small-molecule inhibitors.

The molecular structure of 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate features a pyrimidine ring substituted with amino, hydroxy, and methyl groups, making it an excellent building block for more complex chemical entities. Recent studies highlight its role as a precursor in the synthesis of nucleoside analogs, which are crucial in antiviral and anticancer research. The dihydrate form (CAS No. 388582-41-0) ensures better stability and solubility, addressing common challenges in pharmaceutical formulation.

In the context of current scientific trends, 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate aligns with the growing interest in green chemistry and sustainable synthesis methods. Researchers are actively investigating eco-friendly approaches to produce this compound, reducing reliance on hazardous reagents. This focus on sustainability responds to frequent search queries about "environmentally friendly chemical synthesis" and "green alternatives in organic chemistry," demonstrating the compound's relevance to contemporary scientific discourse.

The analytical characterization of 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate typically involves advanced techniques such as HPLC, NMR spectroscopy, and mass spectrometry. These methods ensure high purity levels required for pharmaceutical applications, addressing common quality concerns in API manufacturing. The compound's spectral data (CAS No. 388582-41-0) has been extensively documented, providing valuable references for quality control laboratories and research institutions.

From a commercial perspective, the global market for pyrimidine derivatives like 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate continues to expand, driven by increasing R&D investments in precision medicine and targeted therapies. This growth reflects in search engine trends showing rising interest in "specialty chemicals for drug discovery" and "high-value pharmaceutical intermediates." The compound's versatility makes it particularly valuable for developing kinase inhibitors and other small-molecule drugs.

Storage and handling recommendations for 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate emphasize maintaining dry conditions at controlled temperatures to preserve its dihydrate form (CAS No. 388582-41-0). Proper storage aligns with Good Manufacturing Practice (GMP) standards, a frequent topic in pharmaceutical industry searches regarding "chemical storage best practices" and "raw material stability." These considerations are particularly important for companies engaged in contract manufacturing of pharmaceutical ingredients.

Recent patent literature reveals innovative applications of 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate in developing fluorescence probes and molecular sensors, expanding its utility beyond traditional medicinal chemistry. This development responds to growing scientific interest in "functional materials" and "smart chemical sensors," frequently searched terms in materials science communities. The compound's ability to coordinate with metal ions opens possibilities in coordination chemistry and catalysis research.

Quality specifications for 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate (CAS No. 388582-41-0) typically include parameters such as purity (>98%), water content, and residual solvent levels. These specifications address common buyer inquiries about "chemical purity standards" and "analytical testing methods," reflecting the compound's importance in regulated industries. The availability of detailed certificates of analysis facilitates its use in GMP-compliant manufacturing processes.

In conclusion, 4-Amino-6-hydroxy-2-methylpyrimidine dihydrate represents a valuable chemical entity with diverse applications across multiple scientific disciplines. Its combination of structural features (CAS No. 388582-41-0) makes it particularly useful for researchers working on medicinal chemistry projects and material science innovations. As scientific inquiry continues to explore new frontiers in molecular design and functional compounds, this pyrimidine derivative remains poised to contribute significantly to future technological advancements.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:388582-41-0)4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE DIHYDRATE
sfd8142
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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