Cas no 384338-23-2 (1-Benzyl-N,4-dimethylpiperidin-3-amine)

1-Benzyl-N,4-dimethylpiperidin-3-amine is a piperidine derivative with potential applications in pharmaceutical and organic synthesis. Its structure features a benzyl group at the 1-position and methyl substituents at the N and 4-positions, offering versatility in chemical modifications. The compound's rigid piperidine backbone enhances stereochemical control, making it useful in the development of chiral ligands or bioactive intermediates. Its amine functionality allows for further derivatization, enabling tailored reactivity in medicinal chemistry or catalysis. The benzyl group may contribute to improved lipophilicity, which can be advantageous in drug design. This compound is typically handled under controlled conditions due to its reactive amine group.
1-Benzyl-N,4-dimethylpiperidin-3-amine structure
384338-23-2 structure
Product Name:1-Benzyl-N,4-dimethylpiperidin-3-amine
CAS No:384338-23-2
MF:C14H22N2
MW:218.337883472443
MDL:MFCD12925759
CID:843459
PubChem ID:9943889
Update Time:2025-06-13

1-Benzyl-N,4-dimethylpiperidin-3-amine Chemical and Physical Properties

Names and Identifiers

    • 1-Benzyl-N,4-dimethylpiperidin-3-amine
    • (1-benzyl-4-methyl-piperidin-3-yl)-methyl-amine
    • 1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE DIHYDROCHLORIDE
    • 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-
    • N,?4-?Dimethyl-?1-?benzyl?-3-?piperidinamine
    • 1-Benzyl-N-methyl-4-methylpiperidin-3-amine
    • (1-Benzyl-4-methylpiperidin-3-yl)methylamine
    • 1-Benzyl-4-methyl-3-(methylamino)piperidine
    • cis-1-Benzyl-N,4-dimethylpiperidin-3-amine
    • AK110568
    • NVKDDQBZODSEIN-UHFFFAOYSA-N
    • BCP14091
    • BCP24253
    • PB25494
    • SB10187
    • RP05087
    • RL06160
    • SY009501
    • SY008580
    • AB0072649
    • (3S,4S)-1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE HYDROCHLORIDE
    • MFCD12925759
    • N,4-Dimethyl-1-benzyl-3-piperidinamine
    • NS00040870
    • SY100364
    • MFCD09878607
    • (3R,4R)-1-Benzyl-3-(methylamino)-4-methylpiperidine
    • AS-32609
    • (1-Benzyl4-methyl-piperidin-3-yl)-methyl-amine
    • rel-((3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine)
    • (1-benzyl-4-methylpiperidin-3-yl)-methylamine
    • CS-0018106
    • CIS-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE
    • N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine
    • PB32723
    • 3-Piperidinamine,N,4-dimethyl-1-(phenylmethyl)-,hydrochloride(1:2),(3R,4R)-rel-
    • SB22746
    • SB37302
    • (1-Benzyl-4-methylpiperidin-3-yl)methylamine; 1-Benzyl-N-methyl-4-methylpiperidin-3-amine
    • DTXSID80433175
    • AKOS016008667
    • CIS-(1-BENZYL-4-METHYL-PIPERIDIN-3-YL)-METHYL-AMINE
    • 384338-23-2
    • 477600-69-4
    • (3R,4R)-1-Benzyl-N,4-dimethyl piperidin-3-amine
    • DA-29717
    • (3S,4S)-(1-Benzyl-4-methyl-piperidin-3-yl)-methyl-amine
    • (3S,4S)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine
    • SCHEMBL690845
    • MDL: MFCD12925759
    • Inchi: 1S/C14H22N2/c1-12-8-9-16(11-14(12)15-2)10-13-6-4-3-5-7-13/h3-7,12,14-15H,8-11H2,1-2H3
    • InChI Key: NVKDDQBZODSEIN-UHFFFAOYSA-N
    • SMILES: N1(CC2C=CC=CC=2)CCC(C)C(C1)NC

Computed Properties

  • Exact Mass: 218.17800
  • Monoisotopic Mass: 218.178298710g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 199
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 15.3
  • XLogP3: 2.3

Experimental Properties

  • Density: 1.00±0.1 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 302.6±35.0 oC (760 Torr),
  • Flash Point: 107.4±16.9 oC,
  • Solubility: Slightly soluble (5.5 g/l) (25 o C),
  • PSA: 15.27000
  • LogP: 2.44520

1-Benzyl-N,4-dimethylpiperidin-3-amine Security Information

1-Benzyl-N,4-dimethylpiperidin-3-amine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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1-Benzyl-N,4-dimethylpiperidin-3-amine Production Method

Additional information on 1-Benzyl-N,4-dimethylpiperidin-3-amine

Comprehensive Overview of 1-Benzyl-N,4-dimethylpiperidin-3-amine (CAS No. 384338-23-2): Properties, Applications, and Research Insights

1-Benzyl-N,4-dimethylpiperidin-3-amine (CAS No. 384338-23-2) is a specialized organic compound belonging to the piperidine derivative family. Its unique structural features, including a benzyl group and dimethylamine substitution, make it a subject of interest in pharmaceutical and chemical research. This article delves into its molecular characteristics, potential applications, and relevance to current scientific trends, addressing frequently searched queries such as "1-Benzyl-N,4-dimethylpiperidin-3-amine synthesis" and "CAS 384338-23-2 uses."

The compound's molecular formula, C14H22N2, highlights its moderate complexity, with a molecular weight of 218.34 g/mol. Researchers often explore its physicochemical properties, including solubility, melting point, and stability, to assess its suitability for various applications. Recent studies have focused on its potential as a building block in drug discovery, particularly for targeting central nervous system (CNS) disorders, aligning with the growing demand for novel neuroactive compounds.

In the context of green chemistry trends, 1-Benzyl-N,4-dimethylpiperidin-3-amine has been investigated for its compatibility with sustainable synthesis methods. Questions like "How to optimize the yield of 1-Benzyl-N,4-dimethylpiperidin-3-amine?" are common among synthetic chemists. Advances in catalytic processes and solvent-free reactions have improved its production efficiency, reducing environmental impact—a key concern in modern chemical manufacturing.

The compound's structure-activity relationship (SAR) is another hot topic, especially in medicinal chemistry forums. Its piperidine core and tertiary amine functionality resemble motifs found in bioactive molecules, sparking discussions about "1-Benzyl-N,4-dimethylpiperidin-3-amine analogs" and their pharmacological potential. Computational modeling and high-throughput screening have accelerated its evaluation as a scaffold for new therapeutic agents.

From an industrial perspective, CAS 384338-23-2 is categorized as a fine chemical, with niche applications in material science and agrochemical research. Its stability under various conditions makes it a candidate for specialized formulations, though handling requires adherence to standard safety protocols. Searches for "1-Benzyl-N,4-dimethylpiperidin-3-amine suppliers" reflect its commercial availability for research purposes.

Emerging trends in AI-driven drug discovery have also brought attention to this compound. Machine learning algorithms analyzing chemical libraries frequently identify 1-Benzyl-N,4-dimethylpiperidin-3-amine as a promising candidate for further study, particularly in GPCR-targeted therapies. This aligns with the increasing integration of computational chemistry and experimental validation in modern research pipelines.

Quality control and analytical methods for 384338-23-2 are critical for ensuring reproducibility. Techniques like HPLC, NMR, and mass spectrometry are routinely employed to verify purity, addressing common concerns such as "How to characterize 1-Benzyl-N,4-dimethylpiperidin-3-amine?" Standardized protocols are essential, given the compound's use in sensitive applications.

In summary, 1-Benzyl-N,4-dimethylpiperidin-3-amine (CAS No. 384338-23-2) represents a versatile heterocyclic compound with multifaceted research implications. Its relevance to drug development, sustainable chemistry, and material innovation ensures continued interest across scientific disciplines. As exploration of its properties and derivatives expands, this compound is poised to contribute to advancements in both academic and industrial settings.

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