Cas no 381721-61-5 (2-(3-fluoropyridin-4-yl)ethan-1-ol)
2-(3-Fluoropyridin-4-yl)ethan-1-ol is a fluorinated pyridine derivative featuring a hydroxyl-functionalized ethyl side chain. This compound is of interest in pharmaceutical and agrochemical research due to its versatile reactivity, particularly as a building block for synthesizing biologically active molecules. The fluorine substitution at the 3-position of the pyridine ring enhances its electronic properties, potentially improving binding affinity in target interactions. The hydroxyl group offers a handle for further functionalization, enabling derivatization into esters, ethers, or other intermediates. Its structural features make it valuable for medicinal chemistry applications, including the development of kinase inhibitors or CNS-targeting compounds. The compound is typically handled under standard laboratory conditions, requiring protection from moisture to maintain stability.
381721-61-5 structure
Product Name:2-(3-fluoropyridin-4-yl)ethan-1-ol
CAS No:381721-61-5
MF:C7H8FNO
MW:141.142925262451
CID:871037
PubChem ID:22321686
Update Time:2025-06-08
2-(3-fluoropyridin-4-yl)ethan-1-ol Chemical and Physical Properties
Names and Identifiers
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- 2-(3-fluoropyridin-4-yl)ethan-1-ol
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- Inchi: 1S/C7H8FNO/c8-7-5-9-3-1-6(7)2-4-10/h1,3,5,10H,2,4H2
- InChI Key: NYLUXSDVCLRAGN-UHFFFAOYSA-N
- SMILES: FC1C=NC=CC=1CCO
Computed Properties
- Exact Mass: 141.058992041g/mol
- Monoisotopic Mass: 141.058992041g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 2
- Complexity: 99.6
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.5
- Topological Polar Surface Area: 33.1?2
2-(3-fluoropyridin-4-yl)ethan-1-ol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-1634962-0.05g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 0.05g |
$256.0 | 2023-06-04 | |
| Enamine | EN300-1634962-0.1g |
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381721-61-5 | 95% | 0.25g |
$546.0 | 2023-06-04 | |
| Enamine | EN300-1634962-0.5g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 0.5g |
$858.0 | 2023-06-04 | |
| Enamine | EN300-1634962-1.0g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 1g |
$1100.0 | 2023-06-04 | |
| Enamine | EN300-1634962-2.5g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 2.5g |
$2155.0 | 2023-06-04 | |
| Enamine | EN300-1634962-5.0g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 5g |
$3189.0 | 2023-06-04 | |
| Enamine | EN300-1634962-10.0g |
2-(3-fluoropyridin-4-yl)ethan-1-ol |
381721-61-5 | 95% | 10g |
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| 1PlusChem | 1P00D66K-50mg |
4-Pyridineethanol,3-fluoro-(9CI) |
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| 1PlusChem | 1P00D66K-100mg |
4-Pyridineethanol,3-fluoro-(9CI) |
381721-61-5 | 95% | 100mg |
$536.00 | 2023-12-17 |
2-(3-fluoropyridin-4-yl)ethan-1-ol Related Literature
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Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
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Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
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Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
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Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
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