Production Method 1

142-45-0

150-76-5

37976-30-0

80-18-2

150-78-7

142207-57-6

Reaction Conditions

1.1 Reagents: Sulfuric acid Solvents: Benzene

Reference

Preparation and photolysis of diaryl esters of acetylenedicarboxylic acid

Alvaro, Mercedes; et al, Tetrahedron, 1992, 48(16), 3437-44

Production Method 2

37976-30-0

37976-30-0

80-18-2

150-78-7

142207-57-6

Reaction Conditions

1.1 Solvents: Benzene
2.1 Reagents: Sulfuric acid Solvents: Benzene

Reference

Preparation and photolysis of diaryl esters of acetylenedicarboxylic acid

Alvaro, Mercedes; et al, Tetrahedron, 1992, 48(16), 3437-44

2-Butynedioic acid, 1,4-bis(4-methoxyphenyl) ester Raw materials

• Acetylenedicarboxylic acid
• Mequinol
• 2-Butynedioic acid, 1,4-bis(4-methoxyphenyl) ester

2-Butynedioic acid, 1,4-bis(4-methoxyphenyl) ester Preparation Products

• 2-Butynedioic acid, 1,4-bis(4-methoxyphenyl) ester (37976-30-0)
• Methyl benzenesulfonate (80-18-2)
• 1,4-Dimethoxybenzene (150-78-7)
• 2H-1-Benzopyran-4-carboxylic acid, 6-methoxy-2-oxo-, methyl ester (142207-57-6)

• 1. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 2. Evolution and characterization of a benzylguanine-binding RNA aptamer?
  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
• 3. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 4. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 5. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)