Cas no 373356-51-5 (1-(3-PENTYL)-PIPERAZINE)

1-(3-Pentyl)-piperazine is a piperazine derivative characterized by its five-carbon alkyl side chain, which influences its physicochemical properties and reactivity. This compound is primarily utilized in organic synthesis and pharmaceutical research, where its structural features enable applications as a building block for more complex molecules. The pentyl substitution enhances lipophilicity, potentially improving bioavailability in drug development contexts. Its piperazine core offers versatile reactivity, allowing for further functionalization at the nitrogen sites. The compound is typically handled under controlled conditions due to its sensitivity to moisture and air. Researchers value it for its balanced solubility profile and compatibility with various reaction conditions, making it a useful intermediate in medicinal chemistry and material science.
1-(3-PENTYL)-PIPERAZINE structure
1-(3-PENTYL)-PIPERAZINE structure
Product Name:1-(3-PENTYL)-PIPERAZINE
CAS No:373356-51-5
MF:C9H20N2
MW:156.268502235413
MDL:MFCD02093554
CID:854062
PubChem ID:2737116
Update Time:2026-04-29

1-(3-PENTYL)-PIPERAZINE Chemical and Physical Properties

Names and Identifiers

    • 1-(3-PENTYL)-PIPERAZINE
    • 1-(1-Ethylpropyl)piperazine
    • 1-(1-Ethylpropyl)piperazine hydrochloride
    • 1-(3-PENTYL)PIPERAZINE
    • 1-pentan-3-ylpiperazine
    • Piperazine, 1-(1-ethylpropyl)-
    • 1-(pentan-3-yl)piperazine
    • MDL: MFCD02093554
    • Inchi: InChI=1S/C9H20N2/c1-3-9(4-2)11-7-5-10-6-8-11/h9-10H,3-8H2,1-2H3
    • InChI Key: IVPIAQOAOCEOKM-UHFFFAOYSA-N
    • SMILES: CCC(CC)N1CCNCC1

Computed Properties

  • Exact Mass: 156.16300
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3

Experimental Properties

  • Boiling Point: 90-92°C/15mm
  • PSA: 15.27000
  • LogP: 1.34690

1-(3-PENTYL)-PIPERAZINE Security Information

  • Hazard Statement: Irritant
  • Hazard Category Code: 22
  • Hazardous Material Identification: Xi

1-(3-PENTYL)-PIPERAZINE Customs Data

  • HS CODE:2933599090
  • Customs Data:

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-(3-PENTYL)-PIPERAZINE Pricemore >>

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Additional information on 1-(3-PENTYL)-PIPERAZINE

1-(3-Pentyl)-Piperazine (CAS 373356-51-5): A Comprehensive Overview of Properties and Applications

1-(3-Pentyl)-piperazine (CAS 373356-51-5) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This piperazine derivative features a unique molecular structure with a pentyl side chain, which contributes to its distinct physicochemical properties and potential applications. As researchers continue to explore novel compounds for various scientific purposes, 1-(3-pentyl)piperazine derivatives have emerged as promising candidates in multiple fields.

The compound belongs to the class of piperazine-based chemicals, which are known for their versatility in medicinal chemistry. With the growing interest in heterocyclic compound synthesis and drug discovery, 1-(3-pentyl)-piperazine offers interesting possibilities for molecular modification and pharmacological activity optimization. Its structural characteristics make it particularly valuable for studying structure-activity relationships in therapeutic agent development.

From a chemical perspective, 1-(3-pentyl)-piperazine demonstrates several noteworthy properties. The compound typically appears as a colorless to pale yellow liquid at room temperature, with moderate solubility in common organic solvents. The presence of both the piperazine ring and alkyl chain contributes to its amphiphilic nature, making it potentially useful in formulation chemistry and drug delivery systems. Researchers have noted that the 3-pentyl substitution pattern may influence the compound's bioavailability and metabolic stability compared to other piperazine analogs.

In pharmaceutical research, 1-(3-pentyl)-piperazine (CAS 373356-51-5) serves as a valuable building block for the synthesis of more complex molecules. The compound's structure allows for various modifications at both the nitrogen atoms of the piperazine ring and the pentyl side chain. This flexibility has led to its use in developing compounds with potential central nervous system activity, though all such applications remain strictly in the research phase. Current scientific literature suggests particular interest in how the pentyl-piperazine moiety might influence receptor binding profiles.

The synthesis of 1-(3-pentyl)-piperazine typically involves multi-step organic reactions, with researchers constantly exploring more efficient and sustainable production methods. Recent advances in green chemistry have prompted investigations into catalytic processes and solvent-free conditions for piperazine derivative synthesis. These developments align with the broader pharmaceutical industry's focus on environmentally friendly synthesis and atom economy principles.

Analytical characterization of CAS 373356-51-5 employs standard techniques including nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and high-performance liquid chromatography (HPLC). These methods ensure proper identification and purity assessment, which are crucial for research applications. The compound's stability under various conditions has been the subject of several studies, particularly regarding its behavior in different pH environments and when exposed to oxidative stress.

Beyond pharmaceutical applications, 1-(3-pentyl)-piperazine has shown potential in materials science. The compound's molecular structure makes it interesting for developing specialty polymers and coordination complexes. Some studies have explored its use as a ligand in catalytic systems or as a component in advanced material formulations. These diverse applications highlight the compound's versatility across scientific disciplines.

The market for piperazine derivatives like 1-(3-pentyl)-piperazine has seen steady growth, driven by increasing research activities in medicinal chemistry and material science. Suppliers typically offer the compound in various quantities to meet different research needs, with purity grades ranging from technical to research-grade specifications. Current trends indicate growing demand for custom synthesis services and derivative libraries based on this chemical scaffold.

Safety considerations for handling 1-(3-pentyl)-piperazine follow standard laboratory protocols for organic compounds. While not classified as highly hazardous, proper personal protective equipment and ventilation are recommended when working with this material. Researchers are advised to consult the latest safety data sheets and conduct appropriate risk assessments before use.

Future research directions for CAS 373356-51-5 may include further exploration of its pharmacological potential, development of novel synthetic routes, and investigation of its physical properties in various formulations. The compound's structural features make it a promising subject for computational chemistry studies and molecular modeling applications. As scientific understanding of piperazine-based compounds expands, 1-(3-pentyl)-piperazine will likely continue to attract research interest across multiple disciplines.

For researchers seeking high-purity 1-(3-pentyl)-piperazine, several specialty chemical suppliers offer the compound with comprehensive analytical documentation. The availability of custom synthesis services allows for the production of specific isotopic labels or structural variants to support advanced research projects. As with all research chemicals, proper regulatory compliance and documentation are essential when acquiring and working with this material.

In conclusion, 1-(3-pentyl)-piperazine (CAS 373356-51-5) represents an interesting and versatile compound within the piperazine chemical family. Its unique structural features and potential applications in pharmaceutical research and materials science make it a valuable subject for ongoing scientific investigation. As research methodologies advance and new applications emerge, this compound will likely maintain its position as an important tool in chemical research and development.

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