Cas no 372-31-6 (ethyl 4,4,4-trifluoro-3-oxobutanoate)

Ethyl 4,4,4-trifluoro-3-oxobutanoate is a versatile chemical intermediate offering high stability and reactivity. Its trifluoromethyl group provides enhanced lipophilicity, facilitating its use in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound's unique properties enable efficient incorporation into complex molecules, streamlining synthetic routes.
ethyl 4,4,4-trifluoro-3-oxobutanoate structure
372-31-6 structure
Product Name:ethyl 4,4,4-trifluoro-3-oxobutanoate
CAS No:372-31-6
MF:C6H7F3O3
MW:184.113192796707
MDL:MFCD00000424
CID:37128
PubChem ID:67793
Update Time:2025-11-06

ethyl 4,4,4-trifluoro-3-oxobutanoate Chemical and Physical Properties

Names and Identifiers

    • ethyl 4,4,4-trifluoroacetoacetate
    • ETHYL 3-OXO-4,4,4-TRIFLUOROACETOACETATE
    • ETHYL 3-OXO,4,4,4-TRIFLUOROBUTYRATE
    • ETHYL 4,4,4-TRIFLUOROACETOACTATE
    • ETHYL 4,4,4-TRIFLUORO-3-OXOBUTANOATE
    • ETHYL TRIFLUOROACETOACETATE
    • 4,4,4-TRIFLUORO-3-OXOBUTANOIC ACID ETHYL ESTER
    • 4,4,4-TRIFLUOROACETOACETIC ACID ETHYL ESTER
    • 4,4,4-Trifluoro-3-ox
    • Ethyl 4,4,4-trifluoroacetoacetate
    • Ethyl-4.4.4-trifluoroacetoacetate
    • ETFAA
    • Ethyl 3-oxo-4,4,4-trifluorobutyrate
    • ethyl 3-trifluoromethyl-3-oxopropanoate
    • ethyl 3-trifluoromethyl-3-oxopropionate
    • Ethyl 4,4,4-trifluor
    • ethyl 4,4,4-trifluoro-3-ketobutyrate
    • ethyl 4,4,4-trifluoro-acetoacetate
    • Ethyl4,4,-Trifluoroacetoacetate
    • Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester
    • Ethyl (trifluoroacetyl)acetate
    • trifluoroacetoacetic acid ethyl ester
    • 4,4,4-Trifluoro-3-oxo-butyric acid ethyl ester
    • ethyl 4,4-trifluoroacetoacetate
    • ETHYL 4,4,4-TRIFLUORO-3-OXOBUTYRA
    • Ethyltrifluoroacetoacetate,98+%
    • ETHYL 4,4,4-TRIFLUOROACETYLACETATE
    • 1-Ethoxy-4,4,4-trifluorobutane-1,3-dione
    • Ethyl 3-oxo-4,4,4-trifluorobutanoate
    • Ethyl 4,4,4-trifluoro-3-oxobutyrate
    • (Trifluoroacetyl)acetic acid ethyl ester
    • Ethyl 4,4,4-Trifluoroacetoacetate,98%
    • CS-B0893
    • Ethyl .gamma.,.gamma.,.gamma.-trifluoroacetoacetate
    • BDBM50121956
    • F0001-1070
    • ethyl-4,4,4-trifluoracetoacetate
    • SCHEMBL77331
    • ethyl triflouroacetoacetate
    • NSC42739
    • AKOS000119777
    • J-802209
    • NSC-42739
    • FT-0626053
    • NSC 42739
    • Acetoacetic acid, 4-trifluoro-, ethyl ester
    • EINECS 206-750-7
    • BCP27409
    • ethyl 4,4,4-trifluoro-3-oxo-butanoate
    • ethyl trifluoro-acetoacetate
    • DTXSID5059905
    • 372-31-6
    • CF3COCH2CO2Et
    • Acetoacetic acid,4,4-trifluoro-, ethyl ester
    • AMY3620
    • D77220
    • Acetoacetic acid, 4,4,4-trifluoro-, ethyl ester
    • EC 206-750-7
    • 4,4,4-trifluoro-acetoacetic acid ethyl ester
    • Q17321524
    • Ethyl omega,omega,omega-trifluoroacetoacetate
    • ethyl 4,4,4,-trifluoroacetoacetate
    • NS00002564
    • ethyl-4,4,4-trifluoroacetoacetate
    • T0810
    • Ethyl 4,4,4-trifluoroacetoacetate, Lonza quality, >=98.0% (GC)
    • EN300-19611
    • Q-102541
    • CHEMBL152164
    • MFCD00000424
    • Ethyl 4,4,4-trifluoroacetoacetate, 99%
    • ethyl-4,4,4-trifluoro-3-oxobutanoate
    • ethyl 3-keto-4,4,4-trifluorobutanoate
    • 4,4,4-trifluoro-3-oxo-butanoic acid ethyl ester
    • trifluoroacetylacetic acid ethyl ester
    • Butanoic acid,4,4-trifluoro-3-oxo-, ethyl ester
    • AI3-52657
    • KM9XB46R5T
    • Ethyl .omega.,.omega.,.omega.-trifluoroacetoacetate
    • Ethyl 4,4,4trifluoro3oxobutanoate
    • Butanoic acid, 4,4,4trifluoro3oxo, ethyl ester
    • Ethyl gamma,gamma,gamma-trifluoroacetoacetate
    • Acetoacetic acid, 4,4,4trifluoro, ethyl ester
    • DB-049085
    • STK400144
    • DTXCID8039299
    • 206-750-7
    • ethyl 4,4,4-trifluoro-3-oxobutanoate
    • MDL： MFCD00000424
    • Inchi： 1S/C6H7F3O3/c1-2-12-5(11)3-4(10)6(7,8)9/h2-3H2,1H3
    • InChI Key： OCJKUQIPRNZDTK-UHFFFAOYSA-N
    • SMILES： FC(C(CC(=O)OCC)=O)(F)F
    • BRN： 608353

Computed Properties

  • Exact Mass: 184.03500
  • Monoisotopic Mass: 184.034729
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 4
  • Complexity: 185
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: 1.4
  • Topological Polar Surface Area: 43.4

Experimental Properties

  • Color/Form: Not available
  • Density: 1.259?g/mL?at 25?°C(lit.)
  • Melting Point: -39 oC
  • Boiling Point: 132°C
  • Flash Point: Fahrenheit: 100.4 ° f
    Celsius: 38 ° c
  • Refractive Index: n20/D 1.375(lit.)
  • PH: 6.2 (10g/l, H2O, 20℃)
  • Solubility: 10g/l
  • Water Partition Coefficient: 10 g/L (20 oC)
  • PSA: 43.37000
  • LogP: 1.07100
  • Solubility: Not available

ethyl 4,4,4-trifluoro-3-oxobutanoate Security Information

  • Symbol: GHS02 GHS07
  • Prompt：warning
  • Signal Word：Warning
  • Hazard Statement： H226,H302,H412
  • Warning Statement： P273
  • Hazardous Material transportation number：UN 3272 3/PG 3
  • WGK Germany：2
  • Hazard Category Code： 10-22-52/53
  • Safety Instruction： S61-S16
  • Hazardous Material Identification： Xn
  • Packing Group：III
  • Hazard Level：3
  • Safety Term：3
  • Packing Group：III
  • Risk Phrases：R10; R22
  • HazardClass：3
  • PackingGroup：III
  • TSCA：T
  • Storage Condition：Store at room temperature

ethyl 4,4,4-trifluoro-3-oxobutanoate Customs Data

  • HS CODE：2942000000
  • Customs Data：

    China Customs Code:

    2918300090

    Overview:

    2918300090 Other aldehydes or ketones without other oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

ethyl 4,4,4-trifluoro-3-oxobutanoate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
E50205-5G
ethyl 4,4,4-trifluoro-3-oxobutanoate
 372-31-6
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 ￥283.56 2023-11-09
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
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XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
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SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
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 ￥142.0 2023-09-07
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
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Ethyl 4,4,4-trifluoroacetoacetate
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 ￥37.0 2023-09-07
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
E72650-25g
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 372-31-6 96%
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SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
E109508-100g
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 ￥140.90 2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
E109508-25g
ethyl 4,4,4-trifluoro-3-oxobutanoate
 372-31-6 98%
25g
 ￥61.90 2023-09-03

ethyl 4,4,4-trifluoro-3-oxobutanoate Suppliers

Hangzhou Cedareal Technology Co., Ltd.
Gold Member
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(CAS:372-31-6)Ethyl 4,4,4-trifluoroacetoacetate
Order Number:CR024
Stock Status:in Stock
Quantity:250kg
Purity:99%
Pricing Information Last Updated:Tuesday, 22 July 2025 16:06
Price ($):10
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:372-31-6)Ethyl 4,4,4-trifluoroacetoacetate
Order Number:sfd2368
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:32
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:372-31-6)三氟乙酰乙酸乙酯
Order Number:LE25881158;LE6606
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:51
Price ($):discuss personally

ethyl 4,4,4-trifluoro-3-oxobutanoate Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

ethyl 4,4,4-trifluoro-3-oxobutanoate Related Literature

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372-31-6 (ethyl 4,4,4-trifluoro-3-oxobutanoate) Related Products

Recommended suppliers
Hangzhou Cedareal Technology Co., Ltd.
(CAS:372-31-6)Ethyl 4,4,4-trifluoroacetoacetate
CR024
Purity:99%
Quantity:250kg
Price ($):10
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:372-31-6)Ethyl 4,4,4-trifluoroacetoacetate
sfd2368
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email