Cas no 369-41-5 (2-fluoro-1-(4-fluorophenyl)ethan-1-one)

2-Fluoro-1-(4-fluorophenyl)ethan-1-one is a fluorinated aromatic ketone with applications in pharmaceutical and agrochemical synthesis. Its key structural features include a fluorine-substituted phenyl ring and a fluoroacetyl group, which enhance its reactivity and stability in selective organic transformations. This compound serves as a versatile intermediate in the preparation of bioactive molecules, particularly in the development of fluorinated analogs with improved metabolic stability and binding affinity. The presence of fluorine atoms at both the phenyl and acetyl positions contributes to its electron-withdrawing properties, facilitating nucleophilic substitution and other key reactions. It is commonly utilized in research settings for the synthesis of fluorinated heterocycles and specialty chemicals.
2-fluoro-1-(4-fluorophenyl)ethan-1-one structure
369-41-5 structure
Product Name:2-fluoro-1-(4-fluorophenyl)ethan-1-one
CAS No:369-41-5
MF:C8H6F2O
MW:156.129449367523
MDL:MFCD21604232
CID:294169
PubChem ID:12602095
Update Time:2025-10-18

2-fluoro-1-(4-fluorophenyl)ethan-1-one Chemical and Physical Properties

Names and Identifiers

    • 2-Fluoro-1-(4-fluorophenyl)ethanone
    • Ethanone,2-fluoro-1-(4-fluorophenyl)-
    • a,4-Difluoroacetophenone
    • Acetophenone,2,4'-difluoro- (6CI,8CI)
    • 2-fluoro-1-(4-fluorophenyl)ethan-1-one
    • ETHANONE, 2-FLUORO-1-(4-FLUOROPHENYL)- (9CI)
    • 2,4'-Difluoroacetophenone
    • 369-41-5
    • SCHEMBL11571
    • MFCD21604232
    • 2-Fluoro-1-(4-fluoro-phenyl)-ethanone
    • EN300-1709056
    • MDL： MFCD21604232
    • Inchi： 1S/C8H6F2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
    • InChI Key： MAKISHZRDILIKX-UHFFFAOYSA-N
    • SMILES： FC1C=CC(C(CF)=O)=CC=1

Computed Properties

  • Exact Mass: 156.03868
  • Monoisotopic Mass: 156.03867113g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 139
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 17.1?2

Experimental Properties

  • PSA: 17.07

2-fluoro-1-(4-fluorophenyl)ethan-1-one Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB280174-1 g
2,4'-Difluoroacetophenone; .
 369-41-5
1 g
 €690.00 2023-07-20
eNovation Chemicals LLC
D574149-25g
2,2-Difluoroacetophenone
 369-41-5 97%
25g
 $1000 2023-09-03
eNovation Chemicals LLC
D574149-100g
2,2-Difluoroacetophenone
 369-41-5 97%
100g
 $2000 2023-09-03
Enamine
EN300-1709056-0.05g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
0.05g
 $174.0 2023-09-20
Enamine
EN300-1709056-0.1g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
0.1g
 $257.0 2023-09-20
Enamine
EN300-1709056-0.25g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
0.25g
 $367.0 2023-09-20
Enamine
EN300-1709056-0.5g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
0.5g
 $579.0 2023-09-20
Enamine
EN300-1709056-1.0g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
1g
 $743.0 2023-06-04
Enamine
EN300-1709056-2.5g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
2.5g
 $1454.0 2023-09-20
Enamine
EN300-1709056-5.0g
2-fluoro-1-(4-fluorophenyl)ethan-1-one
 369-41-5 95%
5g
 $2152.0 2023-06-04

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