Cas no 362049-59-0 (L-Leucine-d)

L-Leucine-d is a deuterium-labeled form of the essential amino acid L-leucine, where one or more hydrogen atoms are replaced by deuterium. This isotopically labeled compound is widely used in metabolic research, protein studies, and NMR spectroscopy due to its stable isotopic signature. Its key advantages include enhanced traceability in kinetic and mechanistic studies, improved resolution in spectroscopic analyses, and reduced interference in mass spectrometry applications. L-Leucine-d is particularly valuable in investigating leucine metabolism, protein turnover, and nutrient absorption pathways. The deuterium labeling ensures minimal perturbation of biological systems while enabling precise tracking in experimental models. It is synthesized under controlled conditions to ensure high isotopic purity and chemical stability.
L-Leucine-d structure
L-Leucine-d structure
Product Name:L-Leucine-d
CAS No:362049-59-0
MF:C6H13NO2
MW:133.185245275497
CID:297094
PubChem ID:87293673
Update Time:2025-06-23

L-Leucine-d Chemical and Physical Properties

Names and Identifiers

    • L-Leucine-3,3-d2 (9CI)
    • L-LEUCINE-3,3-D2
    • L-Leucine-d
    • SCHEMBL1802988
    • L-Leucine-d2
    • D98613
    • CS-0379955
    • 362049-59-0
    • (2S)-2-amino-3,3-dideuterio-4-methylpentanoic acid
    • HY-N0486S12
    • MS-22786
    • DB-297714
    • Inchi: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i3D2
    • InChI Key: ROHFNLRQFUQHCH-YVKXTFNSSA-N
    • SMILES: OC([C@H](C([2H])([2H])C(C)C)N)=O

Computed Properties

  • Exact Mass: 133.107182149g/mol
  • Monoisotopic Mass: 133.107182149g/mol
  • Isotope Atom Count: 2
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 3
  • Complexity: 101
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -1.5
  • Topological Polar Surface Area: 63.3?2

L-Leucine-d Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
L330111-1mg
L-Leucine-3,3-d2
362049-59-0
1mg
$ 64.00 2023-09-07
TRC
L330111-2mg
L-Leucine-3,3-d2
362049-59-0
2mg
$81.00 2023-05-18
TRC
L330111-10mg
L-Leucine-3,3-d2
362049-59-0
10mg
$ 167.00 2023-09-07
MedChemExpress
HY-N0486S12-1mg
L-Leucine-d
362049-59-0 ≥99.0%
1mg
¥900 2025-04-16
MedChemExpress
HY-N0486S12-5mg
L-Leucine-d
362049-59-0 ≥99.0%
5mg
¥3000 2025-04-16
Key Organics Ltd
MS-22786-1mg
L-Leucine-d2
362049-59-0 >97%
1mg
£179.18 2025-02-09
Key Organics Ltd
MS-22786-5mg
L-Leucine-d2
362049-59-0 >97%
5mg
£505.43 2025-02-09

Additional information on L-Leucine-d

Introduction to L-Leucine-d (CAS No. 362049-59-0)

L-Leucine-d, with the chemical compound identifier CAS No. 362049-59-0, is a significant compound in the field of biochemical research and pharmaceutical development. This enantiomer of L-leucine, a naturally occurring alpha-amino acid, has garnered considerable attention due to its unique properties and potential applications in various scientific domains.

The molecular structure of L-Leucine-d differs from its L-enantiomer by the configuration of its optical activity, making it a valuable subject of study in stereochemistry and chiral chemistry. The compound's ability to interact with biological systems in a distinct manner has opened new avenues for research in drug design and metabolic pathways.

In recent years, advancements in synthetic biology and enzyme engineering have enabled the efficient production of L-Leucine-d, making it more accessible for academic and industrial applications. Researchers are exploring its role in asymmetric synthesis, where it serves as a chiral catalyst or intermediate, facilitating the creation of complex molecules with high precision.

One of the most promising areas of research involving L-Leucine-d is its potential use in therapeutic applications. Studies have indicated that this enantiomer may exhibit different pharmacokinetic and pharmacodynamic properties compared to its L-enantiomer, suggesting its suitability for targeted drug delivery systems. For instance, researchers are investigating its efficacy in modulating immune responses and reducing inflammation, which could lead to novel treatments for autoimmune diseases and chronic inflammatory conditions.

The compound's unique interaction with biological receptors has also sparked interest in its role as a precursor for peptide-based drugs. By incorporating L-Leucine-d into peptide chains, scientists aim to develop more stable and bioavailable formulations that can enhance drug efficacy while minimizing side effects. This approach is particularly relevant in the development of protease inhibitors and other enzyme-targeted therapies.

Another emerging application of L-Leucine-d is in the field of nutraceuticals and sports science. Its enantiomeric purity makes it an ideal candidate for supplements designed to optimize metabolic performance and muscle recovery. Studies have shown that dietary supplementation with L-Leucine-d can improve protein synthesis rates and reduce muscle soreness after intense physical activity, making it a popular choice among athletes and fitness enthusiasts.

The synthesis of L-Leucine-d involves sophisticated chemical processes that ensure high enantiomeric purity. Modern techniques such as enzymatic resolution and chiral chromatography have significantly improved the yield and quality of this compound. These advancements have not only reduced production costs but also made it feasible to scale up synthesis for large-scale applications.

In conclusion, L-Leucine-d (CAS No. 362049-59-0) represents a fascinating compound with diverse applications across multiple scientific disciplines. Its unique chiral properties make it indispensable in pharmaceutical research, while its potential in therapeutic development holds great promise for future medical breakthroughs. As synthetic methodologies continue to evolve, the accessibility and utility of this compound are expected to expand even further, driving innovation in both academic and industrial settings.

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