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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylpropanes

4-(1-Hydroxy-1-methylethyl)benzoic Acid (CAS No. 3609-50-5): A Comprehensive Overview

4-(1-Hydroxy-1-methylethyl)benzoic Acid, also known by its CAS number 3609-50-5, is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique molecular structure, which includes a benzoic acid moiety and a 1-hydroxy-1-methylethyl substituent. The combination of these functional groups imparts specific chemical and biological properties that make it a valuable component in various research and industrial processes.

The molecular formula of 4-(1-Hydroxy-1-methylethyl)benzoic Acid is C₁₀H₁₂O₃, and its molecular weight is approximately 180.20 g/mol. The compound is a white crystalline solid at room temperature and is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). Its solubility in water is limited, which can be advantageous in certain applications where controlled solubility is required.

In the realm of medicinal chemistry, 4-(1-Hydroxy-1-methylethyl)benzoic Acid has garnered significant attention due to its potential therapeutic applications. Recent studies have explored its anti-inflammatory and analgesic properties, making it a promising candidate for the development of new drugs targeting pain and inflammation. For instance, a study published in the Journal of Medicinal Chemistry in 2022 reported that derivatives of this compound exhibited potent anti-inflammatory activity in both in vitro and in vivo models.

The hydroxyl group in the 1-hydroxy-1-methylethyl substituent plays a crucial role in the biological activity of 4-(1-Hydroxy-1-methylethyl)benzoic Acid. This functional group can participate in hydrogen bonding and other non-covalent interactions, which are essential for binding to target proteins and modulating their activity. Additionally, the presence of the hydroxyl group can influence the compound's pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME).

In addition to its potential as a therapeutic agent, 4-(1-Hydroxy-1-methylethyl)benzoic Acid has been investigated for its use as an intermediate in the synthesis of more complex molecules. Its reactivity and structural flexibility make it an attractive starting material for various synthetic transformations. For example, researchers have utilized this compound as a building block for the synthesis of novel anti-cancer agents and antimicrobial compounds.

The safety profile of 4-(1-Hydroxy-1-methylethyl)benzoic Acid has also been extensively studied. Toxicological assessments have shown that it exhibits low toxicity at typical exposure levels, making it suitable for use in both research and industrial settings. However, as with any chemical compound, appropriate handling and storage practices should be followed to ensure safety.

In the context of environmental chemistry, the biodegradability of 4-(1-Hydroxy-1-methylethyl)benzoic Acid has been evaluated to assess its environmental impact. Studies have demonstrated that this compound can be effectively degraded by microorganisms under aerobic conditions, reducing its potential for long-term environmental persistence.

The versatility of 4-(1-Hydroxy-1-methylethyl)benzoic Acid extends beyond its direct applications. It serves as a valuable reference compound for analytical methods development and validation. Its well-characterized properties make it an ideal standard for high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS) analyses.

In conclusion, 4-(1-Hydroxy-1-methylethyl)benzoic Acid (CAS No. 3609-50-5) is a multifaceted compound with a broad spectrum of applications in chemistry, biology, and pharmaceuticals. Its unique molecular structure endows it with valuable chemical and biological properties that continue to drive research and innovation in these fields. As ongoing studies uncover new insights into its behavior and potential uses, this compound is poised to play an increasingly important role in advancing scientific knowledge and developing novel solutions to pressing challenges.

• 536-66-3(4-Isopropylbenzoic acid)
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• 7498-54-6(3-Tert-Butylbenzoic acid)
• 5651-47-8(3-Isopropylbenzoic acid)
• 19672-49-2(4-(Diphenylhydroxymethyl)benzoic Acid)
• 97364-15-3(4-(1-Hydroxyethyl)benzoic acid)
• 87771-41-3(1-(3-(2-Hydroxypropan-2-yl)phenyl)ethanone)
• 6328-81-0(Benzoicacid, 4-(diphenylmethyl)-)
• 10196-68-6(Benzoic acid,4-(1,1-dimethylethyl)-, barium salt (2:1))
• 54549-72-3(1-4-(2-hydroxypropan-2-yl)phenylethan-1-one)