Cas no 3592-81-2 (N-Propylcyclohexanamine)

N-Propylcyclohexanamine is a secondary amine featuring a cyclohexyl backbone substituted with an n-propyl group. This compound is of interest in organic synthesis due to its role as a versatile intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its cyclohexane ring provides structural rigidity, while the propylamine moiety enhances reactivity in alkylation and acylation reactions. The compound exhibits moderate basicity and solubility in common organic solvents, facilitating its use in catalytic and stoichiometric applications. Its stability under standard conditions makes it suitable for storage and handling in industrial settings. Researchers value N-propylcyclohexanamine for its balance of reactivity and structural utility in synthetic chemistry.
N-Propylcyclohexanamine structure
N-Propylcyclohexanamine structure
Product Name:N-Propylcyclohexanamine
CAS No:3592-81-2
MF:C9H19N
MW:141.2538626194
MDL:MFCD03210942
CID:1075998
PubChem ID:19178
Update Time:2025-05-26

N-Propylcyclohexanamine Chemical and Physical Properties

Names and Identifiers

    • N-Propylcyclohexanamine
    • N-Cyclohexyl-N-propylamine
    • Cyclohexyl-propyl-amin
    • cyclohexyl-propyl-amine
    • N-propylcyclohexanamine(SALTDATA: FREE)
    • N-propyl-cyclohexylamine
    • Propylamino-cyclohexan
    • Cyclohexylaminopropan
    • EN300-32236
    • BS-37866
    • SCHEMBL26069
    • MFCD03210942
    • 3592-81-2
    • DTXSID60189486
    • cyclohexyl-1-propylamine
    • AKOS000168601
    • Cyclohexanamine, N-propyl-
    • N-(n-propyl)cyclohexanamine
    • N-propylcyclohexanamine, AldrichCPR
    • STK125264
    • cyclohexyl-n-propyl-amine
    • MDL： MFCD03210942
    • Inchi： 1S/C9H19N/c1-2-8-10-9-6-4-3-5-7-9/h9-10H,2-8H2,1H3
    • InChI Key： PXKCSKRXWAZGFK-UHFFFAOYSA-N
    • SMILES： N(CCC)C1CCCCC1

Computed Properties

  • Exact Mass: 141.15200
  • Monoisotopic Mass: 141.151749610g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 3
  • Complexity: 74.8
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 12?2

Experimental Properties

  • Color/Form: No date available
  • Density: 0.8±0.1 g/cm3
  • Melting Point: No date available
  • Boiling Point: 191.3±8.0 °C at 760 mmHg
  • Flash Point: 59.5±15.8 °C
  • PSA: 12.03000
  • LogP: 2.70960
  • Vapor Pressure: 0.5±0.4 mmHg at 25°C

N-Propylcyclohexanamine Security Information

N-Propylcyclohexanamine Customs Data

  • HS CODE：2921300090
  • Customs Data：

    China Customs Code:

    2921300090

    Overview:

    2921300090 Other rings(Alkane,Alkene,Terpene)Monoamine or polyamine(Including its derivatives and their salts). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

N-Propylcyclohexanamine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM305978-5g
N-Propylcyclohexanamine
 3592-81-2 95%
5g
 $665 2021-06-15
SHANG HAI XIAN DING Biotechnology Co., Ltd.
034888-500mg
N-Cyclohexyl-N-propylamine
 3592-81-2
500mg
 3233.0CNY 2021-07-13
SHANG HAI XIAN DING Biotechnology Co., Ltd.
034888-1g
N-Cyclohexyl-N-propylamine
 3592-81-2
1g
 4989.0CNY 2021-07-13
TRC
P839755-50mg
N-Propylcyclohexanamine
 3592-81-2
50mg
 $ 50.00 2022-06-03
TRC
P839755-100mg
N-Propylcyclohexanamine
 3592-81-2
100mg
 $ 65.00 2022-06-03
TRC
P839755-500mg
N-Propylcyclohexanamine
 3592-81-2
500mg
 $ 230.00 2022-06-03
SHANG HAI XIAN DING Biotechnology Co., Ltd.
034888-500mg
N-Cyclohexyl-N-propylamine
 3592-81-2
500mg
 3233CNY 2021-05-07
SHANG HAI XIAN DING Biotechnology Co., Ltd.
034888-1g
N-Cyclohexyl-N-propylamine
 3592-81-2
1g
 4989CNY 2021-05-07
eNovation Chemicals LLC
Y1257487-1g
N-cyclohexyl-N-propylamine
 3592-81-2 95%
1g
 $185 2024-06-06
Enamine
EN300-32236-0.05g
N-propylcyclohexanamine
 3592-81-2 95.0%
0.05g
 $23.0 2025-03-19

N-Propylcyclohexanamine Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:3592-81-2)N-Propylcyclohexanamine
Order Number:A1085897
Stock Status:in Stock
Quantity:10.0g/5.0g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 19:25
Price ($):497.0/334.0

N-Propylcyclohexanamine Related Literature

Additional information on N-Propylcyclohexanamine

Recent Advances in the Study of N-Propylcyclohexanamine (CAS: 3592-81-2) in Chemical and Biomedical Research

N-Propylcyclohexanamine (CAS: 3592-81-2) is a cyclohexylamine derivative that has garnered increasing attention in chemical and biomedical research due to its potential applications in drug development and material science. Recent studies have explored its pharmacological properties, synthetic pathways, and potential therapeutic uses. This research brief aims to summarize the latest findings related to this compound, providing insights into its molecular mechanisms, biological activities, and future research directions.

One of the key areas of interest is the compound's role as a precursor or intermediate in the synthesis of more complex bioactive molecules. A 2023 study published in the Journal of Medicinal Chemistry demonstrated that N-Propylcyclohexanamine can serve as a building block for novel central nervous system (CNS) agents, particularly those targeting neurotransmitter systems. The study highlighted its structural flexibility, which allows for modifications that enhance binding affinity to specific receptors.

In addition to its synthetic utility, recent pharmacological investigations have revealed that N-Propylcyclohexanamine exhibits moderate affinity for sigma receptors, which are implicated in various neurological and psychiatric disorders. A preclinical study conducted by researchers at the University of California, San Francisco, suggested that derivatives of this compound could potentially modulate sigma-1 receptor activity, offering a new avenue for treating neuropathic pain and cognitive impairments.

Another significant development is the exploration of N-Propylcyclohexanamine's potential in material science. A 2024 paper in ACS Applied Materials & Interfaces reported its use as a ligand in the fabrication of metal-organic frameworks (MOFs) with applications in drug delivery systems. The study demonstrated that the compound's amine group facilitates stable coordination with metal ions, resulting in MOFs with high porosity and controlled release properties.

Despite these promising findings, challenges remain in optimizing the compound's pharmacokinetic and safety profiles. Recent toxicological studies have indicated that high doses of N-Propylcyclohexanamine may exhibit hepatotoxicity, necessitating further structural refinements to mitigate adverse effects. Researchers are currently investigating prodrug strategies and formulation techniques to enhance its therapeutic index.

In conclusion, N-Propylcyclohexanamine (CAS: 3592-81-2) represents a versatile compound with broad applications in drug discovery and material science. Ongoing research is expected to uncover additional functionalities and refine its utility in targeted therapies. Future studies should focus on elucidating its structure-activity relationships and exploring its potential in combination therapies for complex diseases.

3592-81-2 (N-Propylcyclohexanamine) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:3592-81-2)N-Propylcyclohexanamine
A1085897
Purity:99%/99%
Quantity:10.0g/5.0g
Price ($):497.0/334.0
Email